ERACTION BETWEEN SEX AND HEREDITARY n this case, a trait is more readily expressed in one sex A father with deutan colorblindness married a woman who is a carrier of the gene for deutan colorblindness. What is the probability of a male offspring having deutan colorblindness? Female offspring who is a carrier
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- Analysis of X-Linked Dominant and Recessive Traits A young boy is color-blind. His one brother and five sisters are not. The boy has three maternal uncles and four maternal aunts. None of his uncles children or grandchildren is color-blind. One of the maternal aunts married a color-blind man, and half of her children, both male and female, are color-blind. The other aunts married men who have normal color vision. All their daughters have normal vision, but half of their sons are color-blind. a. Which of the boys four grandparents transmitted the gene for color blindness? b. Are any of the boys aunts or uncles color-blind? c. Is either of the boys parents color-blind?Analysis of Autosomal Recessive and Dominant Traits Describe the phenotype and primary gene or protein defect of the X-linked recessive disease muscular dystrophy.Variations in Phenotype Expression Define penetrance and expressivity.
- Analysis of X-Linked Dominant and Recessive Traits In the eighteenth century, a young boy with a skin condition known as ichthyosis hystrix gravior was identified. The phenotype of this disorder includes thickening of skin and the formation of loose spines that are sloughed off periodically. This man married and had six sons, all of whom had the same condition. He also had several daughters, all of whom were unaffected. In all succeeding generations, the condition was passed on from father to son. What can you theorize about the location of the gene that causes ichthyosis hystrix gravior?Analysis of X-Linked Dominant and Recessive Traits Suppose a couple, both phenotypically normal, have two children: one unaffected daughter and one son affected with a genetic disorder. The phenotype ratio is 1:1, making it difficult to determine whether the trait is autosomal or X-linked. With your knowledge of genetics, what are the genotypes of the parents and children in the autosomal case? In the X-linked case?Suppose a maternal effect gene exists as a functional dominantallele and a nonfunctional recessive allele. A mother who is phenotypically abnormal produces all normal offspring. Explain thegenotype of the mother
- In humans, one of the genes determining color vision islocated on the X chromosome. The dominant form (C )produces normal color vision; red-green color deficiency(c) is recessive. If a man with normal color visionmarries a color-deficient woman, what is the probabilityof them having a color-deficient son? A color-deficientdaughter?Whyte type canaries are yelllow. A dominant mutant allel of the color gene, designated W causes white feathers. Inheriting two dominant alleles is lethal to the embryo. If a yellow canary is crossed to a white canary, what is the probability that an offspring will be yellow? What is the probability that it will be white? [ autosomal special condition]In humans, unattached earlobes (E) are dominant to attached earlobes (e). If a child is born with unattached earlobes, and a mother with attached earlobes, and a dad with unattached earlobes, what is genotype of the dad? O a. EE or Ee O b. ee O c. Ee O d. Ee or ee O e. EE
- Huntington’s disease, is an incurable neurodegenerative genetic disorder that affectsmuscle coordination and some cognitive functions, typically becoming noticeable inmiddle age. It results from an autosomal dominant gene (H) and there are no carriers ofthe disease. Two parents with Huntington’s disease have an affected child. What is theprobability that their next child will be an unaffected girl if they are not double-dominant?Modes of Inheritance for Single Gene Traits • Autosomal Dominant • Autosomal Recessive • X-linked Dominant • X-linked Recessive • Y-linked • Mitochondrial Let us assume that alleles for these traits follow complete dominance.Cystic fibrosis is a genetic disorder that damages the tissues of the lungs. A – normala - afflicted Which cross between parental genotypes would result in a child expressing this condition?