In the first cycle of fatty acid synthesis via the acyl carrier protein system, the acetyl group on fatty acid synthase condenses withthe malonyl-ACP complex. Draw the structure of the products of this reaction.·Represent ACP by R1. Do not include the free synthase in your drawing.• Be sure to include charges on atoms at pH = 7.• Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner.·Separate multiple products using the + sign from the drop-down menu.?n []

In this reaction:The acetyl group is denoted as CH3-C(=O)-S-R1.The malonyl-ACP is represented as…

Answered: In the first cycle of fatty acid…

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter25: Nitrogen Acquisition And Amino Acid Metabolism

Section: Chapter Questions

Problem 17P

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Similar questions

In the first cycle of fatty acid synthesis via the acyl carrier protein system, the acetyl group on fatty acid synthase condenses with the malonyl-ACP complex. Draw the structure of the products of this reaction. Respresent ACP by R1 do not include free synthase Be sure to include charges on atoms at Ph=7
Consider the complete oxidation of a mixed TAG containing the following fatty acid residues:At carbon 1: cerotic acidAt carbon 2: heptadecanoic acidAt carbon 3: palmitoleic acid Draw the structure of the mixed TAG.
Which of the following statements about de novo purine synthesis is true? (A) Purine nucleotides are formed by separately synthesizing the phosphorylated ribose and the purine ring and then joining them together.(B) GMP is formed first and is used as a precursor to form AMP.(C) The synthesis of AMP from inosinate is driven forward by ATP hydrolysis. (D) GMP synthetase uses NADPH and glutamine to modify the inosinate ring to form GMP.(E) Replacement of the C-1 PPi on PRPP with an amine is required to construct the purine ring on the ribose sugar.
Is the statement during fatty acid biosynthesis, the product detaches from fatty acid synthase complex when the chain length is 16 carbons, wrong or right?
Consider docosanoic acid C12H43CO2H a. Label the alpha and beta Carbons. Show the beta-oxidation in an EXPANDED structure. b. Draw each acyl CoA derived from this fatty acid. c. How many acetyl Co A molecules are formed by complete beta-oxidation? d. How many cycles of beta-oxidation are needed for complete oxidation? e. How many molecules of ATP are formed from the complete catabolism of this fatty acid? Show the complete computation. f. How many moles of ATP per gram of fatty acid is formed from the complete catabolism of the given fatty acid? g. What is the molar mass of the given fatty acid? Solution: Show here the complete computations, [from a to e]
Match each of the enzymes involved in de novo pyrimidine synthesis with the correct description: _______ Dihydroorotate dehydrogenase _______ UMP synthase_______ Carbamoyl phosphate synthetase II _______ TMP synthase _______ CTP synthetase_______ Aspartate transcarbamoylase _______ PRPP synthetase (A) attaches an aspartate to an activated carbamoyl molecule(B) bifunctional enzyme that combines a nitrogenase pyrimidine ring to an activated ribose(C) catalyzes the formation of the activated ribose sugar(D) uses glutamine to add an amine to a preformed nucleotide(E) produces the first cyclic nitrogenase ring during de novo pyrimidine synthesis(F) combines bicarbonate and nitrogen from glutamine in the first step of pyrimidine ring synthesis (G) uses a folate derivative to add a methyl group to a preformed nucleotide
Fatty acid synthesis is largely the reverse of beta oxidation, yet there are some distinct differences. From the statements below, which of the following is inaccurateconcerning fatty acid metabolism? Both processes use mobile electron carriers Both beta oxidation and fatty acid synthase use a carrier group The first step in fatty acid degradation pathway and biosynthetic pathway are regulated C2 unit of acetyl moiety is used in both fatty acid degradation and fatty acid biosynthesis Both processes occur in a unique, specific location (Compartmentalization)
We have stated that fatty acids cannot yield a net gain in carbohydrates in organisms that lack a glyoxalate pathway. Why can odd-chain fatty acids be thought to break this rule to a small extent?
At the conclusion of the first acyl carrier protein cycle in fatty acid synthesis, acetoacetyl-ACP is reduced twice and dehydrated. Draw the structure of final product of this reaction that moves into the next cycle of the ACP reaction.
The second step during elongation of fatty acid chain is catalyzed by B-ketoacyl reducatse. In which 2 ways is this reaction different from the corresponding reaction in fatty acid degradation?
In metabolism, glucose-6-phosphate (G6P)can be used for glycogen synthesis or for glycolysis, among otherfates. What does it cost, in terms of ATP equivalents, to storeG6P as glycogen, rather than to use it for energy in glycolysis?Hint: The branched structure of glycogen leads to 90% of glucose residues being released as glucose-1-phosphate and 10%as glucose.
Calculate the amount of ATP generated from the total oxidation of an unactivated polyunsaturated C21 fatty acid with 5 double bonds.

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