IntroductionApproximately half of the marketed drugs are administered in the form of salts. The type of salt ofany active drug molecule would highly affect the physicochemical and/or the biological properties ofthis drug. In addition, different salt forms of the same drug can be used for different routes ofadministration. Therefore, a proper salt should be selected for a drug molecule to ensure theoptimal therapeutic outcome.The acidic group of NSAIDS is part of their pharmacophoric nucleus, sodium, potassium, and thefree acid forms are used in oral preparation, while diclofenac sodium is used in topical preparations(gel and solution).Question:From the following diclofenac forms diclofenac sodium, diclotenac potassiumMatch the most appropriate diclofenac form to be used for the following patientsMale patient suffering fromDiclofenac sodium or diclofenac potassium no preference :rheumatoid arthritisFemale patient with dysmenorrhea Choose.Geriatric male patient withDiclofenac potassiumcomplicated heart condition

Answered: Image /qna-images/answer/595f23a1-8db6-426b-a940-8eab6332852f.jpg

Male patient suffering from Diclofenac sodium or diclofenac potassium no preference : rheumatoid arthritis Female patient with dysmenorrhea Choose... Geriatric male patient with Diclofenac potassium complicated heart condition

Male patient suffering from Diclofenac sodium or diclofenac potassium no preference : rheumatoid arthritis Female patient with dysmenorrhea Choose... Geriatric male patient with Diclofenac potassium complicated heart condition

Introduction to General, Organic and Biochemistry

11th Edition

ISBN:9781285869759

Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Chapter21: Lipids

Section: Chapter Questions

Problem 21.78P

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Question

Introduction
Approximately half of the marketed drugs are administered in the form of salts. The type of salt of
any active drug molecule would highly affect the physicochemical and/or the biological properties of
this drug. In addition, different salt forms of the same drug can be used for different routes of
administration. Therefore, a proper salt should be selected for a drug molecule to ensure the
optimal therapeutic outcome.
The acidic group of NSAIDS is part of their pharmacophoric nucleus, sodium, potassium, and the
free acid forms are used in oral preparation, while diclofenac sodium is used in topical preparations
(gel and solution).
Question:
From the following diclofenac forms diclofenac sodium, diclotenac potassium
Match the most appropriate diclofenac form to be used for the following patients
Male patient suffering from
Diclofenac sodium or diclofenac potassium no preference :
rheumatoid arthritis
Female patient with dysmenorrhea Choose.
Geriatric male patient with
Diclofenac potassium
complicated heart condition

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