Nu-R + L", are 18 Syl reactions of the type, Nu¯ + RL favored: A) when tertiary substrates are used. B) by using a high concentration of the nucleophile. c) when L is a strong base. D) by use of a non-polar-solvent. E) by none of the above.

Which reaction or statement regarding nucleophilic substitutions is incorrect? A) C₁ + 2 H2O ноттон + 2 HCI B) ta CI+MeOH to + HCI C) D) The rate-limiting step in SN1 reactions is the initial step, loss of the leaving group. Nucleophilic substitution reactions that follow second-order kinetics involve complete inversion of configuration.

Like acid chlorides, acid anhydrides react with alcohols in the presence of pyridine to form esters. For the following reaction : (a) Draw a circle around the nucleophile ; (b) Draw a square around the electrophile; (c) Put a star next to the base; (d) Draw the structure of the tetrahedral intermediate in the box below. Then draw a reasonable 3-step arrow pushing mechanism for the reaction.

What is more nucleophilic CH3O- or CH3S- ? The solvent isn't mentioned, or it can be assumed it's aprotic if needed, or in other words it doesn't interfere with nucleophilicity.

Kindly answer this question iv, v & vi

Give detailed Solution with explanation needed. don't use Ai for answering this

The question is: "Draw the curved arrow mechanism for the reaction between pentan-2-one and (CH3)3O– in t-butanol to form an enolate. Draw all electrons and charges on both resonance structures. Then answer the question about the reaction." I got the initial arrows correct, but am not entirely sure what the carbanion intermediate would look like and then what the curved arrows would be to convert it to its final oxanion form

Show the arrow pushing the following. mechanismsĜ for the formation of a) Isoa camy! acetate DOctul Acetate Octy!

2. Like acid chlorides, acid anhydrides react with alcohols in the presence of pyridine to form esters. For the following reaction: (a) Draw a circle around the nucleophile; (b) Draw a square around the electrophile; (c) Put a star next to the base; (d) Draw the structure of the tetrahedral intermediate in the box below. Then draw a reasonable 3-step arrow pushing mechanism for the reaction. pyridine + но Structure of tetrahedral intermediate Mechanism:

Q4. Nucleophilic attack at carbonyl with loss of carbonyl oxygen. For this question, answer AT LEAST FIVE of the SIX parts. (a) For the FOUR reactions listed below, draw structures of the major organic products. (i) (ii) (iii) HO OH ●... NMe₂NH₂ cat. dry HCI H Ph₂pⓇ THF