The enzyme Lysozyme is present in human nasal mucus and catalyzes the breakdown of a component of the cell wall of certain bacteria, causing them to burst. Hence, Lysozyme helps protect against bacterial infections. One experimental investigation of Lysozyme gave the result in Table 1. Here, [S]o is the initial substrate concentration and V is the initial rate of the breakdown reaction. [S]o (µM) 1.0 2.0 4.0 10 20 Table 1 V (μM/sec) 0.14 0.22 0.31 0.42 0.48 Use a graphical method to determine the Michaelis constant, Kè, and the maximal rate, V max. What initial reaction rate would be expected for [S]0=200μM? In these experiments the concentration of lysozyme was 0.0025 µM. Calculate the maximal turnover, kcat, for lysozyme under the investigated conditions.

The enzyme Lysozyme is present in human nasal mucus and catalyzes the breakdown of a component of the cell wall of certain bacteria, causing them to burst. Hence, Lysozyme helps protect against bacterial infections. One experimental investigation of Lysozyme gave the result in Table 1. Here, [S]o is the initial substrate concentration and V is the initial rate of the breakdown reaction. [S]o (µM) 1.0 2.0 4.0 10 20 Table 1 V (μM/sec) 0.14 0.22 0.31 0.42 0.48 Use a graphical method to determine the Michaelis constant, Kè, and the maximal rate, V max. What initial reaction rate would be expected for [S]0=200μM? In these experiments the concentration of lysozyme was 0.0025 µM. Calculate the maximal turnover, kcat, for lysozyme under the investigated conditions.

Curren'S Math For Meds: Dosages & Sol

11th Edition

ISBN:9781305143531

Author:CURREN

Publisher:CURREN

Chapter21: Heparin Infusion Calculations

Section: Chapter Questions

Problem 1.3P

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