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- Consider two different proteins that are leaving from the Golgi in order to arrive in their common destination, a lysosome. In order for these two different proteins to be sent to the same place, what should they have in common? A) They must have the same primary structure B) They must have been imported into the cell by endocytosis. C) They must have the same tertiary structure D) They probably have the same glycosylation pattern. ..Why nonhomologous end-joining (NHEJ) is helpful ?List three potential organelle destinations for a free ribosome (cytosolic-produced) protein via transmembrane protein translocation:
- What interactions could a phosphorylation of a GPCR facilitate?Protein structure and function: a) Name two common post-translational modifications of proteins in the cell that will affect their structure/function. b) What are prions? Briefly describe their structure and function. C) Explain the principles of protein folding and significance of urea and Bmercaptoethanol in the experimental procedures addressing this question.What is transpeptidation and why is it important to both the celland to clinical medicine?
- Based on what you know about the structure of GPCRs, they must have: a)One internal start transfer sequence near the C terminus b)One ER signal sequence near the N terminus c)One internal start transfer sequence and one internal stop transfer sequence d)Multiple internal start transfer sequences and multiple internal stop transfer sequences choose the right answerThere are many organelles that appear similar to lysosomes yet they are endocytotic vesicles. What is the accepted histochemical method to unequivocally identify a lysosome from other similar appearing organelles?Explain why E is the correct choice. In eukaryotes, after the ribosomes complete a synthesis, one might expect a) a new protein molecule to appear inside the ER b) a protein to insert into the cell membrane, c) and increase in the amount of enzyme in the cell organelles, d) the primary, secondary and tertiary levels of protein structure would form inside the ER. e) All are possible.
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