When is it safe to assume that the change from initial concentration (+/- x) is small enough to be negligible/ignore when doing equilibrium calculations for weak acids and bases?

Chemistry for Today: General, Organic, and Biochemistry
9th Edition
ISBN:9781305960060
Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Publisher:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Chapter9: Acids, Bases, And Salts
Section: Chapter Questions
Problem 9.84E
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When is it safe to assume that the change from initial concentration (+/- x) is small enough to be negligible/ignore when doing equilibrium calculations for weak acids and bases? Be specific!

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