You are studying protein folding and quality control. You hypothesize that protein, CNX, is an ER resident protein that is required for the process of protein folding and quality control. You decide to mutate thegene that encodes CNX so that it is localized to the nucleus instead of the ER so you can observe the effects on protein folding and quality control. What kind of mutation would you make that would result inthe protein localizing to the nucleus?A. Delete the N terminal hydrophobic signal sequence and add a KDELB. Delete the N terminal hydrophobic signal sequence and add a NLSC. Delete the N terminal hydrophobic signal sequence and add a NESD. Delete the KDEL sequence and add a NLS Select the most accurate explanation for how vesicular transport occurs when a receptor is moving from the plasma memberane to the late endosome/lysosome.A. Endosomes containing the receptor are transported by myosin II walking towards the minus end of microtubules. Endosomes are targeted to the late endosome/lysosome by Rab and SNARES facilitatemembrane fusion.B. Endosomes containing the receptor are transported by myosin V walking towards the minus end of microtubules. Endosomes are targeted to the late endosome/lysosome by Rab and SNARESfacilitate membrane fusion.OC. Endosomes containing the receptor are transported by dyenin walking towards the minus end of microtubules. Endosomes are targeted to the late endosome/lysosome by Rab and SNARES facilitatemembrane fusion.D. Endosomes containing the receptor are transported by kinesin-13 walking towards the plus end of microtubules. Endosomes are targeted to the late endosome/lysosome by clathrin and SNARESfacilitate membrane fusion.

Name: You are studying protein folding and quality control. You hypothesize
Uploaded: 2024-03-20T06:42:55.000Z
Channel: Bartleby
Description: You are studying protein folding and quality control. You hypothesize that protein, CNX, is an ER resident protein that is required for the process of protein folding and quality control. You decide to mutate thegene that encodes CNX so that it is l