Andrew Wakefield - Unethical Research

In order to investigate more about Wakefield’s study, Brian Deer, a journalist of British Medical Journal, carefully talked to the parents of all children who were participated in the study. Interestingly enough, he revealed the fraud behind Wakefield’s research. The Lancet, the journal that reported Wakefield’s study, retracted the paper soon afterwards (Deer). However, the real trouble still exists. Though it has been proved by many researchers that the MRR doesn’t cause autism, many people perceive the vaccine as a threat. Dr.Nemeroff once said “it is quite difficult to get the cognitive sewage out of the water even after the real sewage is gone” (Greene).

Andrew Wakefield is a former gastroenterologist and medical researcher who was discharged from his medical register in the UK, because of his dishonest research paper he released back in 1998, that analysed a possible link between measles, mumps and rubella (MMR) vaccine and the presence of autism and bowel disease (Godlee, F., et al, 2011). Wakefield's research generated a substantial scare for the MMR vaccine and MMR vaccination rates began to drop because parents were concerned about the risk of autism after vaccination (DeStefano, F., Chen, R.T., 1999). After the paper was published by the Lancet medical newspaper, other reviews were trying to repeat Wakefield's conclusions,

Wakefield had lied about the medical histories of the children and the duration between symptoms and vaccination (Deer, 2011). Child number two had shown symptoms six months after being vaccinated, but Wakefield’s paper claimed that child number two showed symptoms two weeks after being vaccinated. The child’s medical history stated that symptoms had been shown six months after vaccination. Actually, only child number two had “regressive autism.” Furthermore “regressive autism” is where the child seems to normally develop, but they start to lose skills like speech. The paper stated that all of the children had autism, but three out of the twelve did not have autism at all (Deer, 2011). To strengthen his claim, Wakefield lied about the amount of children with autism. Two of the three children, who did not have autism, were siblings (Deer, 2011). Both of these siblings had bowel problems before getting vaccinated. Wakefield stated that the bowel problems were linked to the autism. The siblings did not even have autism and their bowel problems started before even getting vaccinated. The effects of this are quite dangerous. In the UK, vaccination rates dropped below 85%, and in some areas below 75% (Kolodziejski, 2014, p.165). In Londen England, vaccination rates were as low as 58% (Burgess, Burgess, & Leask, 2006, p.3921). Parents felt that they would rather have their child get mumps, measles, or

This led to the support of various unproven vaccine-autism theories by parents in both the UK and America. After findings of intestinal disease in children with autism, Wakefield claimed that separating the MMR into three different vaccinations would be safer. Since then, Wakefield’s research has been discredited, he was charged with serious professional misconduct by the General Medical Council for violating several ethical practices, and he was investigated for failing to disclose conflict of interest – a pending patent on a rival measles vaccine (Gross, 2009). Although false, many still believe wholeheartedly that vaccines are harmful.

The topic of childhood vaccinations and the dangers that accompany them has been a topic of controversy in contemporary times. At the near edge of the twenty-first century, a man named Doctor Andrew Wakefield released a study which created a mass uproar in both parents and health professionals alike. Parents were panicked as to whether or not they should have their young child vaccinated (in fear of their acquiring autism), and health professionals fearful that the population percentage of people acquiring measles, mumps, or rubella (for it was the M.M.R. vaccination that the parents feared in particular) would rise to a number which would lead to a mass risk of disease. Despite Wakefields’ study, the truth persists in all types of experiments related to vaccination. Whether being tested in a replication of Wakefields’ study or in any other, vaccines have been proven to work at preventing disease and display no causation of autism.

In fact, The BMJ, or the British Medical Journal, chimed in on Wakefield’s paper. “By the time the paper was finally retracted 12 years later, after forensic dissection at the General Medical Council’s (GMC) longest ever fitness to practise hearing, few people could deny that it was fatally flawed both scientifically and ethically” (Godlee, “Wakefield’s”). Furthermore, Wakefield’s license to practice medicine was stripped away by Britain’s General Medical Council because of misconduct, including the time Wakefield paid his son’s friends £5 each to take blood samples during his son’s birthday party (Burns, “British”). More recent studies also prove that the vaccine-autism link is nonexistent. One study, performed by the Journal of Pediatrics, found that, “ … of MCO members, increasing exposure to antibody-stimulating proteins and polysaccharides in vaccines during the first 2 years of life was not related to the risk of developing an ASD” (Destefano, “Increasing”). In other words, having a young child exposed to the ingredients of vaccines does not result in the child developing autism (Destefano, “Increasing”).

Science is supposed, to tell the truth, but because humans are the ones performing the experiments sometimes there are flaws.  For instance, Andre Wakefield in 1998 of Royal Free Hospital in London, England, said the Measles, Mumps, and rubella vaccines were to blame for autism. Andrew Wakefield came to this conclusion based on results found in eight out of twelve children. His results were then published in a medical journal called Lancet. Andrew Wakefield condemnation of vaccination caused the public to become scared ("vaccinations and Autism". . .). Andrew Wakefield's research was the starting point of the conspiracy theory that the measles, mumps, and rubella vaccinations cause Autism. Furthermore, It made people, especially parents of autistic kids, question and lose trust in vaccinations. Without Wakefield's research people, might not question vaccinations as much as

Andrew Wakefield’s research and the movie “Vaxxed” has provoked skepticism about vaccines’ safety and generated a lack of vaccinated children. Wakefield has tried to spread false

Wakefield published a study on the effects of the Measles, Mumps, and Rubella (MMR)-vaccine, specifically the “mercury” based and the vaccine instigating the onset of autism (Wakefield para 3). Wakefield’s study involved 12 individuals whose medical background was altered in order to support his study (Goodlee para 2). After 12 years of Wakefield’s research being published, his findings were found to be inaccurate. Many doctors and scientists alike have proven his theory wrong, causing the magazine that published the article to fully retract it (Goodlee para 2). However, the damage caused by Wakefield’s false findings has yet to be undone. The number in vaccinations dropped and the number of deadly diseases ultimately rose (Goodlee para 8). Despite study after study proving that Wakefield blatantly falsified his findings, many parents including, celebrities like Jenny McCarthy, continue to advocate against vaccinations and blame the MMR-vaccine for her child’s autism diagnosis.

One such factor helping to manifest these large-scale epidemics is a study from 1998 by Andrew Wakefield, which claimed that there was a direct link between autism and the MMR (measles, mumps, and rubella) vaccine (Smith 1). As a result, many parents refused to vaccinate their children out of fear, and vaccine-preventable diseases like measles began reappearing more in both America and Britain, the place where Wakefield conducted his study (Cohen 2). Although a later investigation by the British Medical Journal discovered that Wakefield had distorted or altered the medical records of all twelve of the study’s participants and that he had been paid $674,000 USD by lawyers attempting to sue vaccine manufacturers, the atmosphere of apprehension surrounding vaccines is still strong among many individuals, and especially parents (Cohen 1-2). But despite all the controversy and the scientifically unsupported arguments of anti-vaccine sympathizers,

Andrew Wakefield and other 12 co-authors published a study in the Lancet in 1998 that suggested a relationship between measles, mumps, and rubella (MMR) and autism. In other words, Wakefield and associates suggested that the vaccine for MMR could predispose children to autism. The paper received massive publicity despite the researchers having used a sample size that was not representative (n=12), the research design was uncontrolled as well as conclusions being speculative (Sathyanarayana Rao & Andrade, 2011). Consequently, the vaccines for MMR plummeted since parents feared that vaccinating their children against MMR could predispose their children to autism.

In the 1950s, the polio vaccine was introduced and life in America was forever changed. We vaccinated children against polio and many other diseases and America as a whole became a much healthier place. Soon, parents could quite reasonably expect to have a happy and healthy child. Vaccines were like miracle drugs. Then, in 1998, everything changed. Andrew Wakefield, a physician from the United Kingdom, published a study stating that he had found a link between the MMR vaccine and autism. Thus began the dangerous trend of refusing vaccines for children. Although many people believe vaccines to be dangerous, in fact, they are one of the safest medical procedures done.

The current issue I have selected to discuss is vaccinations. In particular, I will be addressing the anti-vaccination movement that has gained popularity in recent years and the contributing biases that influenced its emergence. One event stands out at as a major contributing factor to the growth of the anti-vaccination movement, the 1998 study by Andrew Wakefield that was published by the English medical journal, Lancet. This study claimed to show a connection between the MMR vaccine and autism. Even though it was just one small study, the media picked it up and it became hugely publicized.

In Amy Wallace’s article “An Epidemic of Fear: How Panicked Parents Skipping Shots Endangers Us All” a majority of parents in America have come to believe and accept the ideology that vaccination is an unnecessary greed and actually the cause for autism in children. In her article Wallace fights against this misconception and tries to persuade her readers that vaccines are not only crucial for the health of children, but also harmless. Wallace writes a persuasive article regarding the importance of vaccination and disproves the theory of them being the causation of autism, by presenting convincing data, statistics and brings attention to faulty appeal to authority. Wallace also appeals to authority that persuades those who already agree with her argument though her use of such a public figure alienates her target audience.

Live Science Contributor, Stephanie Pappas tell us that, “Wakefield was getting money from lawyers planning on suing vaccine makers, and he owned a patent on an alternative to the MMR (measles) vaccines,” [2] this statement is clear evidence of fraudulent activity and proves that Wakefield had corrupt reasons for undergoing this study in the first place. The second flaw to Wakefield's paper was the questionable practises of his study, for starters he based his study on twelve children that he “cherry picked,” and “although the paper claimed that cognitive problems developed a few days after the MMR vaccine, a simple investigation of hospital records revealed that wasnt so; and in several cases parents reported problems before the vaccine,” [2]. In summary, the investigation was sloppy and provided no tangible evidence that links autism to the MMR vaccine. Furthermore, it should be noted that the the link between autism and vaccines is purely coincidental, the symptoms of autism typically appear at around the age that vaccines are administered, in fact director of the Vaccine Education Centre at the Children's Hospital of Philadelphia, Dr Paul Offit confirms this says, “Children get their first dose of the MMR vaccine at 12 to 15 months, the age at which autism symptoms typically