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Asthma Research Paper

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In the world of pharmaceuticals, “there is a continuing interest in developing once-daily medications to further simplify treatment regimens and improve patient compliance”, especially when treating COPD and Asthma 1. “Suitable therapies for asthma and COPD need to provide targeted, long lasting and consistent efficacy” 2. This research paper summarizes the current clinical findings of a new drug called Abediterol a LABA. In addition to this, we will also summarize the most current research on abediterol versus the current SABA’s albuterol, and LABA’s salmeterol, indacaterol, olodaterol, and vilanterol in its treatment of asthma. Abediterol is a promising new potent LABA, currently in Phase II development. This is a drug that is used as a once daily treatment for chronic obstructive pulmonary disease COPD and asthma in combination with an Inhaled Corticosteroids ICS 3.

Asthma is one of the most common diseases, it affects nearly 300 million people worldwide, and 25 million here in the US 4. “Worldwide, the number is expected to increase to 400 million by 2025” 4. Asthmas primary symptom is airflow obstruction, which results from narrowing of the airways in the lungs. Some common causes of asthma include smooth muscle contraction, inflammation, excessive mucus production, and foreign body or allergens. …show more content…

This local and systemic inflammation can affect daily functioning and quality of life 5. COPD patients usually have symptoms of chronic bronchitis and emphysema. The inflammation of the lungs causes the development of thickened walls, which causes mucus to build up blocking the airways leading to symptoms of bronchitis 5. In emphysema alveoli in the lungs are gradually destroyed, leading to decreased surface area needed for gas

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