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Battle against HIV/AIDS in South Africa
Introduction
HIV/Aids pandemic is high in South Africa as compared to any other country in the world. Recent statistic show that 12% of South Africa’s population lives with the virus and including young children the percentage rises to 18% of the total population. Other neighboring countries such as Botswana also have high prevalence rates and this means that almost all southern African countries rank top among the most infected nations not only in Africa but the world around. In the past few years the number of south Africans being diagnosed of HIV has been rising and even though the infections among adolescents particularly male have been dropping the damage this infection is causing remains substantial both socially and economically. Based on demographic grouping the most infected are females below the age of 40. And of the females infected about 80% are aged between 20-24 years. Infection among males stands below 40% with those aged above 30 years being the most infected. The fact that aids is high in South Africa more than any other country in Africa makes it necessary to understand the reasons behind it. Steinberg (2008) in his book “Sizwe 's test: a young man 's journey through Africa 's AIDS epidemic” fails to understand why many people still die in south Africa despite the emergence of antiretroviral drugs. He however realizes that “stigma” remains the greatest challenge in as far as HIV/AIDS is
Nearly three decades ago, there was an increase in deaths of HIV in sub-Saharan Africa. Developing countries have experienced the greatest HIV/AIDS morbidity and mortality, with the highest prevalence rates recorded in young adults in sub-Saharan Africa. In South Africa over three million people are killed by this disease (Macfarlene3). After this epidemic spreaded in Africa and killed people it branched out to other countries in the world.
The term Human Immunodeficiency Virus is commonly known as (HIV), which is a virus that attacks the immune system of humans by destroying the amount of CD4 cells in their bodies. Without CD4 the human body is unable to fight against diseases, which can lead to Acquired Immune deficiency syndrome known as AIDS for short. The first case of the HIV/AIDS virus in the U.S. occurred in the early 1980’s. The first spark of the virus was found in San Francisco with couple of homosexual Caucasian American males. Today African Americans account for the largest proportion of HIV and AIDS in this country, represent approximately 13% of the U.S. population, but accounted for an estimated 44% of new HIV infections in 2010(the last year a study was
Human Immunodeficiency Virus is HIV that develops into AIDS, which is Acquired immunodeficiency syndrome. This virus starts to break down white blood cells, as a result the immune system starts to deteriorate and our greatest shield cannot fight any longer (Mayo Clinic, 2016). The CDC (2015) states, that over 1.2 million people live with HIV in the United States and most who are infected are oblivious of their disease. Healthy people 2020 has declared HIV a public health crisis in the United States, and continues to sweep the nation with more than 500,000 new cases each year (HealthyPeople2020,2016).
Many people are unaware of their health status further increasing transmission of disease in young adult African American(AA) women age 18-24. Human Immunodeficiency Viruses (HIV) infects and also destroy blood cells (i.e. lymphocytes) that the body need to fight off infection (Mays 2011). African American women HIV positive, age 18-24 the magnitude of issue of the health disparity in this particular population will be addressed along with the many factors of social and health determinants. The health concern is towards the increase of transmission among young AA mothers and their children who are the health outcomes in many ways than one. The many social and health determinants that affect the women today are on going cycles that have yet to be broken. African American women make 64% of new infection cases for HIV. African american obtain a vulnerability unlike other minorities. The health population’s culture and stigma has played an important role in the community. The concern for AA women is the increase of new cases and most importantly the spread of the disease to these women’s children. The mortality rate of AA women with HIV is 47.1% as of 2012. (Siddiqi 2015)
According to recent statistics from the Centers for Disease Control, approximately 1.2 million individuals in the United States have HIV (about 14 percent of which are unaware of their infection and another 1.1 million have progressed to AIDS. Over the past decade, the number of HIV cases in the US has increased, however, the annual number of cases remains stable at about 50, 000 new cases per year. Within these estimates, certain groups tend to carry the burden of these disease, particularly the gay, bisexual, and men who have sex with men (MSM) and among race/ethnic groups, Blacks/African American males remain disproportionately affected. (CDC)
In The Invisible Cure, Helen Epstein talks about why HIV/AIDS rate is so high in Africa compared to the rest of the world. Through the book, she gives us an account of the disease and the struggles that many health experts and ordinary Africans went through to understand this disease, and how different African countries approached the same problem differently. Through this paper, I will first address the different ways Uganda and Southern African countries, South Africa and Botswana in particular, dealt with this epidemic, and then explain how we can use what we have learned from these African countries to control outbreaks of communicable disease elsewhere around the world.
In the 1980s, a mysterious disease began to take the lives of Americans. With the cause unknown, a fear grew among Americans. An unusually high rate of people was becoming sick with strange and rare diseases. When experimental treatments failed to work, people died. This mysterious disease is what we now know as HIV–Human Immunodeficiency Virus. In the past thirty-five years, the HIV has taken many turns in history. Although we do not hear about HIV and AIDS now, it is still a prevalent issue in the United States and in the world.
The Human Immunodeficiency Virus (HIV) has been a major health concern due to its rapid ability to spread and high death rate. Although HIV can be found all around the world, it is most common in Africa. For decades, both sociologist and scientist have struggled to determine the specific causes that led to the wide spread of HIV in Sub-Saharan Africa. The novel The Invisible Cure: Why We Are Losing the Fight Against AIDS in Africa by Helen Epstein tells her journey as a molecular biologist trying to find a cure for HIV across Sub-Saharan Africa. Throughout her journey, Epstein is able to experience the various problems that the majority of people in the African continent face. The problems that Epstein encounters can easily be fixed, but because of the lack of effective government control in most areas they aren’t. Through cultural, political, and social factors, Epstein depicts the roots of the HIV outbreak and the possible cures that can be found within Uganda’s collective efficacy.
Human immunodeficiency Virus also known as HIV is a sexually transmitted disease. It attacks your body's immune system. The virus destroys CD4 cells, which help your body fight diseases. HIV damages your immune system and it leads to acquired immune deficiency syndrome also known as AIDS. AIDS is the final stage in HIV, and it’s a disease where severe loss of the body's cellular immunity occurs. The disease lowers the resistance to infection and malignancy. Anyone can get HIV/AIDS. Men, women, and children, of all different races and descents can get infected with the virus. People who are gay or straight can also be infected with HIV/AIDS. There is currently no cure for HIV/AIDS. HIV treatments may reduce
HIV and AIDS have affected millions of people throughout the world. Since 1981, there have been 25 million deaths due to AIDS involving men, women, and children. Presently there are 40 million people living with HIV and AIDS around the world and two million die each year from AIDS related illnesses. The Center for Disease Control estimates that one-third of the one million Americans living with HIV are not aware that they have it. The earliest known case of HIV was in 1959. It was discovered in a blood sample from a man in Kinshasa, Democratic Republic of the Congo. Looking further into the genetics of this blood sample researchers suggested that it had originated from a virus going back to the late 1940’s or early 1950’s. In 1999,
Sub-Saharan Africa is the region of the world that is most affected by HIV/AIDS. The United Nations reports that an estimated 25.4 million people are living with HIV and that approximately 3.1 million new infections occurred in 2004. To put these figures in context, more than 60 percent of the people living with the infection reside in Africa. Even these staggering figures do not quite capture the true extent and impact that this disease causes on the continent. In 1998, about 200,000 Africans died as a result of various wars taking place on the continent. In that same year, more than 2 million succumbed to HIV/AIDS (Botchwey, 2000).
HIV is the human immunodeficiency virus that causes AIDS. A member of a group of viruses called retroviruses, HIV infects human cells and uses the energy and nutrients provided by those cells to grow and reproduce. AIDS (acquired immunodeficiency syndrome) is a disease in which the body's immune system breaks down and is unable to fight off certain infections, known as "opportunistic infections," and other illnesses that take advantage of a weakened immune system. When a person is infected with HIV, the virus enters the body and lives and multiplies primarily in the white blood cells. These are the immune cells that normally protect us from disease.
HIV, or the Human Immunodeficiency Virus, is a virus which damages and kills cells of the immune system. It attacks the T-cells, key cells of the immune system, and uses them to make copies of itself. After being infected with the virus it progressively interferes and eventually destroys the immune system's ability to fight the anti-genes. HIV may develop into the syndrome AIDS, the Acquired Immunodeficiency Syndrome. HIV is an STD - a sexually transmitted disease - and therefore most commonly it is spread through sexual contact, and the virus mainly enters the body through the penis, mouth, lining of the vagina or vulva during sexual activity. HIV can also be spread through sharing syringes or needles with someone who is infected with the
Stein et al. (2015) similarly conducted a prospective, randomized clinical trial comparing effects of three ART treatments on carotid wall intima-media thickness (IMT). This was a multicenter project taking place over 26 institutions and included a total 328 participants. Subjects included HIV infected individuals who were not on any ART regimen and did not have known cardiovascular disease or diabetes mellitus. Participants who reported use of statins, fish oil, fibric acid derivatives or niacin were excluded from the study. All subjects received tenofovir/emtricitabine and additionally were randomized equally between one of three regimens of atazanavir/ritonavir (ATV/r), darunavir/ritonavir (DRV/r), or raltegravir (RAL). Right common
The Human Immunodeficiency Virus (HIV) is a Lentivirus (a subgroup of retrovirus) that causes HIV infection and over time Acquired Immunodeficiency Syndrome (AIDS). AIDS is a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive, without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. HIV infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages, and dendritic cells. HIV infection leads to low levels of CD4+ T cells through a number of mechanisms, including Pyroptosis of abortively infected T cells, apoptosis of uninfected bystander cells, direct viral killing of infected cells, and killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections.