Case Study: Tuskegee Study

The experiment first began in 1932, in a small county within the Macon County of Alabama area. In this are rate of syphilis was up by 35%. Interestingly, the setting of the study was conducted at the Tuskegee Institute, which we know now to be Tuskegee University. The study conducted of 399 men, 201 out of the 399 were used as the control group. The control group contained of those who actually didn’t have the diseases. The study also targeted those who were poor and illiterate. A lot of those patients had the slightest clue to which they were being tested for, only being told they had “bad blood”. The doctors participating in the study thought it would be vital; to not inform

This essay examines the Tuskegee Syphilis Study, wherein for 40 years (1932-1972) hundreds of black men suffering from advanced syphilis were studied but not treated. The 40-year study was controversial for reasons related to ethical standards; primarily because researchers knowingly failed to treat patients appropriately after the 1940s validation of penicillin as an effective cure for the disease they were studying. To explore the role of the racism in the controversial study, this essay analyzes the article written by Allan M. Brandt.

The issues that were involved in the violation of the ethical principles involving human subjects include racism, paternalism, informed consent, truth telling, scientism, and whistle blowing. There were other issues that were involved in this study: double standards, maleficence, and the use of deception in research among others. The issue of racism was seen clearly in this study. Four hundred black persons were infected and two hundred served as a control group. Caucasians were not enrolled in this study. This was a violation of justice because the subjects were not treated

The Tuskegee Syphilis experiment (The official name was Tuskegee Study of Untreated Syphilis in the Negro Male) began in the 1930’s. It was an experiment on African Americans to study syphilis and how it affected the body and killed its victims done by Tuskegee Institute U.S. Public Health Service researchers. The initial purpose of the Syphilis study “was to record the natural history of syphilis in Blacks” (Tuskegee University, “About the USPHS Syphilis Study,” par. 2). The study was necessary because syphilis was a disease that didn’t yet have an official cure (when the study began in the 30’s). There were 600 men in all; 399 had syphilis and 201 served as a control group for the experiment. The

In Macon County, Alabama, about 40% of African Americans had syphilis. Syphilis caused by a spirochete bacterium that is contracted sexually. In the 1930’s it had relatively no cures or treatments. Syphilis progresses into three stages, the last of which begins to attack the several organ systems of the individual. The victim may become paralyzed, blind and/or deaf; develop heart problems or a mental illness, or other symptoms (Gray 37-38). They decided that they wanted to compare and contrast how blacks and whites develop the disease and the effects on each race. Years before the study of the Negro was set to begin, a similar study for whites was conducted in Oslo, Norway. This study was a retrospective look into the effects of untreated syphilis in whites. The retrospective study used case histories of those who had syphilis when they died not living patients. The U.S. Public Health Service decided to use African Americans in Macon County in the experiment. Originally titled “The Effects of Untreated Syphilis in the Negro Male” the experimentations took place at the Tuskegee Institute which is why the study is generally named the Tuskegee Syphilis Study (Jones 93-94). The Rosenwald Fund, a foundation that funded many programs that were used in the betterment of African-Americans began funding this project. After the Stock Market crash of 1929, and the start of the Great Depression, the Rosenwald Fund has to withdraw all the funds that they

However, it was more difficult to test all the subjects than expected. SInce they didn’t want to be suspected of their experiment they had to open the selection to anyone with syphilis. It was also difficult to get the participant to enlist so they had to offer free care and therapy, which led to more participants. When they enlisted they were told they had “bad blood” and were being treated for it. Since they weren’t really be treated the doctors had to come up with a way so that it seemed like they were being treated. They would give most of the subjects mercurial ointment and the rest a small dosage of neoarsphenamine. The last step of their experiment was to give the subjects “a spinal tap to test for evidence of neuro-syphilis.” Throughout the 40 years, the USPHS told many of local doctors and the Army to not treat those patients. They were told to prefer those patients back to the USPHS if they did visit them. In the 1950s, some subjects were given penicillin, but only a few were given an effective doses. Those who were given antibiotics had threatened the experiment, which later ended in 1970s. The last main point of the article is the HEW final report. There was a panel by the HEW that discusses the two issues, which were the informed consent from the subject and also should they have provided penicillin to the subjects. In the final report, it was found that by the HEW that the USPHS didn’t have the intentions of providing penicillin

(Tuskegee University) Out of the 600 African American men, the United States Public Health Service refused to treat 399 of the men who were diagnosed with syphilis with late stage. From these men, “perhaps more than 100 had died directly from advanced syphilitics lessons.” (Brandt) From the Tuskegee University, it’s stated that the doctors and researches used the excuse of bad blood in order to get men participating.

The men had to consequently suffer and deal with pus filled sores covering their body, including their mouths, just so the scientists could study the lasting effects of untreated syphilis. Suffering from syphilis was not what the men signed up for, and to them, there seemed to be no way out of the suffering. Even research by the Center for Disease Control (CDC), “Found nothing to show that subjects were ever given the choice of quitting the study.” Even though the men most likely felt trapped, they still had to go on with their everyday lives, which included their healthy significant others.

The Tuskegee Syphilis Study of 1932 studied approximately six hundred twenty-five “disadvantaged rural black men” (Pozgar, 2016) that both had syphilis and did not have syphilis. This study, named "Tuskegee Study of Untreated Syphilis in the Negro Male" (Centers for Disease Control and Prevention, 2013), was conducted by the Public Health Service from 1932 to 1972, however was only projected to last 6 months (Centers for Disease Control and Prevention, 2013). The purpose of the study was to show the effects of untreated syphilis. The men involved were led to believe that were receiving treatment for their various conditions but were actually not receiving treatment. The men participating in the study were not informed of the purpose of the study or what treatments they were receiving. The study concluded in 1972 and began many more years of investigation and hearings on behalf of the participants that suffered during the trials.

The book BAD BLOOD: THE TUSKEGEE SYPHILIS EXPERIMENT by James H. Jones was a very powerful compilation of years of astounding research, numerous interviews, and some very interesting positions on the ethical and moral issues associated with the study of human beings under the Public Health Service (PHS). "The Tuskegee study had nothing to do with treatment … it was a nontherapeutic experiment, aimed at compiling data on the effects of the spontaneous evolution of syphilis in black males" (Jones pg. 2). Jones is very opinionated throughout the book; however, he carefully documents the foundation of those opinions with quotes from letters and medical journals.

According the to the Centers for Disease Control and Prevention, the Tuskegee Syphilis Experiment was conducted in 1932 by the Public Health, which included 600 black men as their test subjects. Of the 600 men, 399 had syphilis and 201 didn’t (CDC). The men were told that they were being treated for “Bad Blood” and didn’t have any knowledge of being included in a study (CDC). In exchange for their services, researchers offered the men free medical exams, burial insurance, and free meals (CDC). The study was called “ The Tuskegee Study of Untreated Syphilis in the Negro Male” (CDC).

None of the men knew that the “bad blood” which coursed through their veins was contagious. None understood how the disease was transmitted; no one explained to them that congenital syphilis was passed on from female to fetus. It was an experiment based on deception, a characteristic that it retained for the next forty years. Through a historical analysis of the experiment several questions arise, particularly the issues of the men’s participation in the experiment and the black professionals who witnessed the study. Why did these Black men take part in this study? Why did the Black health professionals not challenge the study? The answers to these questions are interconnected and lies captive in a term Jones calls racial medicine (Jones 15).

The Tuskegee syphilis study was the longest held study in the United States. The study continued for 40 years, from 1932 to 1972 which at that time a civil rights attorney ended the study and filed a lawsuit claiming the study carried out unethical methods. The Tuskegee study included only African American males with the diagnosis of syphilis. The study initially was to determine if the African American male progressed differently with the diagnosis compared to the white male. However, throughout time it appeared that the study moved to see how African American

The Tuskegee Syphilis Study took place over a time period of almost fifty years. During the investigation, John Heller, Director of the Venereal Disease unit for the PHS was interviewed, one of his comments was; “The men’s status did not warrant ethical debate. They were subjects, not patients; clinical material not people” (Tuskegee University). The way these men were treated and looked upon and

The Tuskegee syphilis experiment was an experiment conducted by the U.S. Public Health Service between 1932 and 197. In this experiment, the investigators recruited 399 African American share croppers infected with syphilis. Their purpose was to study the effects of the untreated disease. In 1932 the standard treatments for syphilis were toxic and it was questionable whether or not they actually worked. The goal, at the experiment’s beginning, was to determine if a patient was better off without such toxic treatments. The experimenters also hoped to develop effective methods of treating each stage of syphilis. They also hoped to be able to justify treatment programs for blacks. However, by 1947 penicillin became the new and effective medical