Effects Of Hormones On Breast Cancer

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Lindsey Yee
Bio 110
22 July 2015

The Effects of Hormones on Breast Cancer

Breast cancer is a popular disease that many people are afraid of. It is the growth of altered genes that create malignant tumors starting in a female or male’s breast tissue. Cancer has a reputation of being caused by hormones, but that may not always be the case. Hormones are chemicals that work as chemical messengers in the body and affect the duties of cells and tissues. The ovaries in premenopausal and postmenopausal women usually produce the hormones, like estrogen and progesterone. The hormone estrogen develops and maintains the female sex features and progesterone have to do with women 's menstrual cycle and pregnancy. In a breast cancer cell, it …show more content…

Like the Nurses’ Health Study, in 2002, a study called the Women’s Health Initiative published a theory that the breast cancer rates in the U.S decreased because of the reduced use of HRT. The results showed that HRT increased breast cancer risk (Breast Cancer Infographic). Because estrogen promotes the growth of cancers that are hormone-receptor positive, HRT is not a treatment for cancer but increases the risk of cancer because it is used to increase estrogen levels and hormone therapy blocks and lowers estrogen levels (The American Cancer Society) (Armstrong). The second therapy is hormone therapy. This therapy is said to treat breast cancer but is not used alone. Hormone therapy is usually paired with chemotherapy or radiation. Hormone therapy slows or stops the growth of hormone-sensitive tumors by preventing the production of hormones (National Cancer Institute). Breast cancer has cells with hormone receptor- positive. Estrogen makes hormone-receptor-positive breast cancers grow by reducing the amount of estrogen one can reduce the risk of hormone-receptor-positive breast cancers coming back (Armstrong). The most common hormone therapy drug that blocks estrogen development is Tamoxifen. This drug (often a pill) stops the hormone from binding to the breast cancers cells, ultimately preventing the cell to divide and

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