Efficacy Of Rabies In Humane

Rabies is a fatal disease transmitted by the bite of an infected mammal. The disease travels from the saliva of the infected animal, into the wound of its victim, eventually attacking the brain and nervous system. At that time the virus get to the brain, the victim develops symptoms salivating, walking in circles, loss of appetite, fear of water, and aggression. After

Rabies is a highly infectious viral disease that can easily ruin and eventually end the lives of both humans and animals alike. Rabies comes in two forms for animals. It comes in the form of paralytic rabies, which is the kind that puts you in paralysis right from the beginning, skipping the symptoms of agitation and excitability. Rabies also appears in the form of furious rabies, which is completely different in the way that it makes the victim restless, vicious and agitated. When humans get rabies, their symptoms start out with simple headaches and fevers and later progresses to terrible things such as becoming hydrophobic because of painful throat spasms and paralysis. A definite diagnosis of rabies needs lab analysis of

Rabies is a viral disease that causes severe swelling of the brain in humans and other mammals (Prabhavathy, H., & Palanivel, K. M. 2015). Rabies is caused by lyssaviruses and is spread when a diseased animal cuts or bites another mammal. Bat bites are the most common source of rabies in humans, in the Americas, less than five percent are caused by dogs (Prabhavathy, H., & Palanivel, K. M. 2015). With an extensive treatment known as the Milwaukee protocol, few people have survived the rabies infection after the manifestation of the symptoms (Prabhavathy, H., & Palanivel, K. M. 2015).

the contagiousness of anthrax ,diseases, bacteria and viruses, began with his study of why a

This article argues the burden of rabies globally and country specific. The key concern of this article is having adequate amounts of data to appropriately report the issue of canine rabies in specific areas. Per the article, rabies is one of the greatest fatal infections that affect humans and other mammals of this world. The article specifically declares canine rabies being the most dangerous strain out of majority cases of rabies. Canine rabies is referred to infection which is spread from a bite of a domestic dog. Domestic dogs are connected with wildlife in industrialized and developing countries which causes them to be a greater threat. Canine rabies is vastly imperative because it is the key cause for over 99% of human deaths worldwide. Now rabies in fact can be 1prevented through prompt administration of post-exposure prophylaxis (PEP) to victims of bites by rabid animals, and infection can be eliminated at source through sustained mass vaccination of reservoir populations. In developing countries rabies is an endemic which has been poorly controlled. 1A major challenge to estimating the burden of rabies is the absence of reliable surveillance data for countries where the disease is most prevalent. 1Official reporting of incidence data on rabies and rabies exposures remains desperately poor

More than 70 viruses, parasites, fungi and bacteria are considered dangerous pathogens to the humanity [1]. Vaccine administration has been the most creative and precious discovery in the twentieth century [2]. For most of these pathogens vaccines are present and other vaccines under establishing, in phase three clinical trial, for almost all the other viruses such as influenza virus B and bacteria such as staphylococcus aureus and about half of the parasites such as leishmania [1]. Vaccines have a major impact in reducing childhood mortality and saving millions of human beings [2]. Vaccines are the most efficient and cost-effective measure to prevent several serious and life threatening infectious diseases. The successful global eradication

scientist Paul Efland discovered a cure for rabies in a simple vaccine. One bitten by a rabid animal and getting rabies there is a small period of time to where you have to get to the emergency room. This vaccine was first tested on mice that will cure rabies even after this disease has spread to the brain. Usually the disease would have reached the mice brain by day three, but by day six the mice have already shown telltale physical symptoms meaning that the infection has become fatal and can not be cured

The rabies virus, a zoonotic disease that can be transferred from animals to humans through the saliva or brain tissue of an infected animals into a cut or lesion of a human. It has also been reported that humans were able to contract the virus through the process of having cornea and organ transplants. Once a human has been infected with the virus, it effects the nervous system by traveling through the nerves to the

Cattle, sheep and goats do not normally spread the disease by bites and are therefore referred as end host. Human beings can, however be infected by them through working in the mouths of cattle with bare hands. People often think that a bovine with rabies has something stuck in its mouth and try to remove the obstruction. The virus is able to enter the human body through open wounds, sores or scratches on the hands. Even the teeth can transmit rabies.

Since its delivery method is the significant problem to its effectiveness, the use of the vaccine could not be realistic despite the fact that the DNA vaccine is developing (Robinson, Ginsberg, Davis, Johnston, & Liu, 1997). Also, the mutation of the host human’s chromosomal DNA is still doubtable and if it could happen, the cell growth could be affected and it is possible to create a chance of developing cancer (Robinson, Ginsberg, Davis, Johnston, & Liu, 1997). In addition, the human body could develop a tolerance the vaccine because of the amount of the vaccine derived protein. In other words, the small amount of antigen could be ignored by the human immune system (UK Health Centre, 2015). At last, to overcome these disadvantages, there is no suspicion about great cost and time consuming (Glenting & Wessels, 2005).

Rabies belongs to the order Mononegavirales, family Rhabdoviridae, genus Lyssavirus. (7) Six other lyssaviruses also cause rabies (Lagos Bat, Mokola Virus, Duvenhage Virus, European Bat Virus 1 & 2, and Australian Bat Virus). (7) This is not, however, an exhaustive list as public health experts suspect other pathogens will be discovered. (7) Because rabies is a virus (and not a bacterium), this microbe is neither gram positive nor negative.

This bullet-shaped, enveloped RNA virus is one of the most formidable, zoonotic, neurologic diseases due to the prognosis almost invariably fatal in both humans and animals. Rabies is a genotype 1 Lyssavirus and can be found throughout the world, with the exception of Taiwan, Australia, New Zealand, Iceland, the United Kingdom, Japan, the majority of Western Europe, Fiji, Hawaii and Guam (Sykes, 2014).

Rabies transmission can also occur if saliva or central nervous system tissue from a rabid animal contacts a fresh wound or mucous membrane (MCDC, 2012). Various routes of transmission have been documented and include contamination of mucous membranes (i.e., eyes, nose, and mouth), aerosol transmission, and corneal transplantations (ADPH, 2010). Post-exposure prophylaxis is recommended in rare instances of non-bite exposure, such as inhalation of aerosolized virus by spelunkers exploring caves inhabited by infected bats or by laboratory technicians homogenizing tissues infected with rabies virus without appropriate precaution (MHLTC, 2013).

Rhabdovirus (rabies) is a viral disease that is transmitted through the saliva or tissues from the nervous system from an infected mammal to another mammal. It’s an RNA virus who’s genome encodes 5 proteins designated as N, P, M, G, and L. The arrangement of these proteins and the RNA genome determine the structure of the rabies virus. It belongs to the order of mononegavirales which are virus with a non-segmented negative stranded RNA genome. Under the rhabdoviridae family is the lyssavirus genus which rabies virus falls under. Rabies is a zoonotic disease (meaning it can be transmitted between animals and humans).

Abstract: Rabies is a dangerous disease that affects both animals and humans. Rabies is caused by the lyssa virus and is almost 100% fatal. The majority of the people infected die from it but there have been a small number of miraculous cases where people have survived. One very special case took place in the life of Jeanna Giese because she recovered without the use of rabies vaccines. There are four FDA approved vaccines for public usage but they are not guaranteed to cure. Rabies affects many people around the world, especially in underdeveloped nations. It is a very serious disease and is preventable if treatment is received before any symptoms show up.