How Do Pentraxins Help Detect Alzheimer 's Disease? Humans?

Statement of Purpose: Today, I want to tell you about three aspects of Alzheimer’s disease.

Even today, after so much study, Alzheimer’s is not fully understood. However, researchers do agree that this degenerative disease is caused by the gradual buildup of fibrous protein compounds in the brain, which are known in the scientific world as amyloids. These amyloids in the brain area act like plaque and as a result of their presence, the normal brain functioning is disrupted.

Today we are going to look at three different types of Dementia and what they are, there symptoms, and the treatments.

5) There are two types of genes that play a role in whether a person will develop Alzheimer’s disease or not.

The alzheimer’s disease is a progressive disease that destroys memory and other important mental functions. Alzheimer's is not a normal part of aging and only up to 5 percent of people with the disease have early onset Alzheimer's (also known as younger-onset), which often appears when someone is in their 40s or 50s. This disease doesn’t have a cure, but there are treatments for symptoms available and research still continues to find the answer to cure this bad disease. Also, an interesting fact is that ninety percent of what we know about Alzheimer's has been discovered in the last 15 years. Lastly, Alzheimer's is a progressive disease, where dementia symptoms gradually worsen over a number of years. In its early stages, memory loss is mild, but with late-stage Alzheimer's, individuals lose the ability to carry on a conversation and respond to their environment. It’s the sixth leading cause of death in the United

Alzheimer’s disease is a complex illness that affects the brain tissue directly and undergoes gradual memory and behavioral changes which makes it difficult to diagnose. It is known to be the most common form of dementia and is irreversible. Over four million older Americans have Alzheimer’s, and that number is expected to triple in the next twenty years as more people live into their eighties and nineties. (Johnson, 1989). There is still no cure for Alzheimer’s but throughout the past few years a lot of progress has been made.

Alzheimer 's is a slow and debilitating disease that generates multiple problems with cognitive skills including; memory, thinking and behavior. (MedlinePlus, 2015) It is especially painful for friends and family members who see their loved ones progressively lose their memory and ability to function as they normally have. Symptoms typically develop gradually and progressively get worse over time, becoming severe enough to put the person afflicted with the disease unable to complete daily tasks and placing themselves at risk. (MedlinePlus, 2015) Alzheimer’s is the most common diagnosed condition of dementia. (MedlinePlus, 2015) Sixty to eighty percent of dementia cases are designated as Alzheimer’s. (MedlinePlus, 2015) Although the greatest known risk factor for Alzheimer’s is increasing age, it is not considered a normal part of aging. The majority of those diagnosed with Alzheimer 's are approximately sixty-five and older. However, Alzheimer’s is not just a disease affected by the older age populations. About 5 percent of people with Alzheimer’s experience early symptoms and the onset Alzheimer 's and most often appears in their forties or fifties. As stated above, Dementia or Alzheimer’s symptoms gradually worsen over time. In the early stages, it is common to experience mild memory loss. Eventually, the ability to carry on a conversation is lost. The sixth leading cause of death in the United States is Alzheimer’s. After Alzheimer’s symptoms become publicly

Even today, doctors use the same technique that Dr. Alzheimer used to observe the plaques and tangles in the brain. (2) Studies show that the risk of developing Alzheimer’s disease increases with age. Almost 20 percent of Americans between the years of 75 and 84, and almost half of those that are 85 years and older suffer from Alzheimer’s disease (3). One out of every 10 persons that are 65 years of age and older are said to be victims of Alzheimer’s disease, yet even some early-onset victims might be in their 40s and 50s (4).

Alzheimer’s disease in many ways is not yet defined. It is a progressive disease afflicting between 5 and 15 percent of people over 65. Additionally, it is not restricted to the elderly, reportedly having

Alzheimer 's disease (AD) was discovered by a German doctor Alois Alzheimer in 1906 when he found amyloid plaques and neurofibrillary tangles in the autopsy of a woman who died of an unknown mental disease. The extracellular amyloid plaque deposits, composed of insoluble amyloid-Beta peptide were hypothesized to be the main etiological factor. “The most important abnormality is an excess of Amyloid-beta peptides brought about through either overproduction or failure in degradation.” (Uzun, Kozumplik, & Folnegović-Smalc, 2011) Later, it was discovered that intracellular neurofibrillary tangles composed of hyper-phosphorylated, helically-paired tau

The risk factors can increase the possibility of having Alzheimer’s, but isn’t exactly linked to cause Alzheimer’s. Age, genetics, gender, cardiovascular disease, having down syndrome, depression, immune system malfunctions, endocrine (hormonal) disorders, slow-acting viruses or bacteria, vitamin deficiencies, exposure to electromagnetic fields and accumulation of metals such as zinc, copper, iron and aluminum in the body, or previous head injuries are the risk factors. If you’re older, a female, and have had other people in your bloodline with Alzheimer’s then your chances of getting Alzheimer’s are significantly increased. The chances of getting Alzheimer’s doubles every five years after the age 65. Some research says that the chances of getting Alzheimer’s

Alzheimer’s disease (AD), is a type of dementia that no one would ever want their grandmother or grandfather to suffer from, as it destroys memory and other important mental functions of its sufferer. Alzheimer's disease is currently ranked as the sixth leading cause of death in the United States. While the age 65 and older is its target age, it has consumed the lives of over 1.9 million people. The brain begins to show signs of damage in the hippocampus, the part of the brain essential in forming memories. As more neurons die, parts of the brain then begin to shrink. By the final stage of Alzheimer’s, damage is widespread, and brain tissue has shrunk significantly. The idea that Alzheimer’s disease is related to age in 1974 was introduced

The research into Alzheimer's Disease has come a long way since 1906 when it is was discovered by Alois Alzheimer. He detected microscopic brain tissue changes called senile and neuritic plaques in deceased patients. These are chemical deposits consisting of protein molecules called Amyloid Precursor Protein(APP) that are fundamental components of a normal brain. However in the brain of an Alzheimer patient, an enzyme cuts the APP apart and leaves fragments in the brain tissue. These combined with degenerating nerve cells cause the plaques or lesions. These lesions are found in many sections of the brain including the hippocampus which regulates emotion and memory, the basal forebrain, and especially the basal nucleus of Meynert and the cortex, where the memory function is located.(2) Another sign of a diseased brain are neurofibrillary tangles, which are malformations within nerve cells.

Alzheimer’s, a severe irreversible form of dementia, is now a very prevalent issue in the aging population. Scientists are just beginning to understand what Alzheimer’s is, what causes Alzheimer’s and how to prevent it. Although research has come a long way, “Alzheimer’s disease, as science tries to grasp it, seems to slip through our fingers. The complex interaction of neurochemistry, genetics, environment, lifestyle and personality all play a part in how individuals experience Alzheimer’s. ~ Harry Clayton

Alzheimer is a disease that affects the elderly most. The disease was discovered by Dr. Alois Alzheimer in the year 1906 when he was examining a female’s brain. He found out that the woman displayed memory loss, language problems and some inexplicable changes in behavior. The disease was named after the doctor who was a German psychiatrist and a neuropathologist. Alzheimer’s disease is a degenerative brain disorder that leads to memory loss, personality changes, and language problems (Gilbert & Julie 2). The disease is mostly diagnosed in people over the age of 65 years, though there is a small minority of people under the age of 50 who get the disease. Studies show that 1% of a whole population aged between the ages 65-75 have severe