Oxycontin Research Paper

Last year there were over 64,000 reported opioid-related deaths in the United States – making it the leading cause of accidental death in people under the age of 50 in this country (Katz). Opioids, also referred to as painkillers, have become a growing problem over the past two decades particularly in rural communities all across the country where the death rates are higher per capita compared to the death rate in cities (“America’s Opioid Epidemic is Worsening”). These narcotics, such as codeine, fentanyl, hydrocodone, morphine and oxycodone are extremely addictive and, as a result, this silent killer has quadrupled the overdose death toll since 1999

Opioid drugs are some of the most widespread pain medications that we have in this country; indeed, the fact is that opioid analgesic prescriptions have increased by over 300% from 1999 to 2010 (Mitch 989). Consequently, the number of deaths from overdose increased from 4000 to 16,600 a year in the same time frame (Mitch 989). This fact becomes even more frightening when you think about today; the annual number of fatal drug overdoses in the Unites States now surpasses that of motor vehicle deaths (Alexander 1865). Even worse, overdose deaths caused by opioids specifically exceed those attributed to both cocaine and heroin combined (Alexander 1865).

Unfortunately, the producers of Purdue Pharma’s Oxycontin didn’t realize how easy it was to break that outer shell, and have instant access to twelve hours worth of drugs. This realization by the public, caused a devastating and widespread increase in addition to the drug, and the transition to the drug seen as a “street” drug. Unlike many other types of medications where you can be prescribed a dosage and stay on that dosage for a long time. "Your body adapts to Oxycontin. Essentially, you require more to get the same effect, and what happens is a steady escalation in dosage. After a year or two of treatment, you are on extremely high levels of these drugs (Tunnel, 2005)". Oxycontin transitioned from a lifeline for people with chronic pain, to an addiction caused by a greedy corporation.

Many people may not realize this but multiple states, including Michigan, are facing an epidemic. It is not a disease, however, it is a heroin epidemic. In a country where addictive opioid pain-killer prescriptions are handed out like candy, it not surprising heroin, also known as smack or thunder, has become a serious problem. The current heroin epidemic Michigan is facing, as are dozens of other states, has spiraled out of control in recent years. In Michigan, some of the areas hit hardest by this drug are in the southern portion of the state, like Wayne, Oakland, and Monroe Counties. The connection between painkillers and heroin may not be clear, but this is because both are classified as opioid drugs, and therefore cause many of the same positive and negative side effects. As a country, we are currently the largest consumer of opioids in the world; almost the entire world supply of hydrocodone (the opioid in Vicodin) and 81% of the world’s oxycodone (in Percocet and OxyContin) is used by the United States (Volkow). Along with consuming most of the world’s most common opioids, we have gone from 76 million of these prescriptions in 1991 to 207 million in 2013 – constantly increasing except for a small decrease starting in 2012 (Volkow). This widespread use has caused numerous consequences from increasing emergency room visits – for both painkillers and heroin – to sky-rocking overdose cases all over the country (Volkow). Michigan, unfortunately, currently has one of the

In the early 1990’s many doctors were hesitant in prescribing narcotics because they were seen as harmful and habit forming. Purdue Pharma the creator of OxyContin changed the ways of the drug industry. Purdue changed the mindset of many physicians and family doctors inconveniencing them that the new to the market drug was revolutionary, with promises of quick pain relief that last up to 12 hours. With marketing adds like “Remember, effective relief just takes two” Purdue Pharma convinced doctors that it was virtually impossible to become addicted (HARRIET RYAN, 2016). The rise of OxyContin started in 1996. OxyContin

Like most drugs, Oxycontin can be abused in many different forms. It can be taken orally, crushed up and snorted, or dissolved and injected. By crushing it up or injecting it, it causes an instant feeling of euphoria when it enters the body. Oxycontin is often called “poor man’s heroin” due to the fact that they both have comparable effects. When the user is exposed to constant amounts of

The United States currently faces an unprecedented epidemic of opioid addiction. This includes painkillers, heroin, and other drugs made from the same base chemical. In the couple of years, approximately one out of twenty Americans reported misuse or abuse of prescriptions painkillers. Heroin abuse and overdoses are on the rise and are the leading cause of injury deaths, surpassing car accidents and gun shots. The current problem differs from the opioid addiction outbreaks of the past in that it is also predominant in the middle and affluent classes. Ultimately, anyone can be fighting a battle with addiction and it is important for family members and loved ones to know the signs. The cause for this epidemic is that the current spike of opioid abuse can be traced to two decades of increased prescription rates for painkillers by well-meaning physicians.

To understand how fentanyl has become so prevalent recently, we must look back at the cause of this opioid epidemic. Opioids were once a niche drug, but in the mid 90s OxyContin was released by the manufacturer, Purdue Pharma LP. Purdue advertised this drug to doctors by saying that the risk of addiction from opioids was overstated and that OxyContin

To most people, pain is a nuisance, but to others pain controls their life. The feeling discomforts us in ways that can sometimes seem almost imaginable. These feelings can lead to many different side effects if not dealt with or diagnosed. These effects can include depression, anxiety, and incredible amount of stress. The truth about pain is that it is vital to our existence. Without the nervous system responding to pain, we would have no idea if we were touching a hot stove, being stuck by a porcupine’s needles, or something else that could leave a lasting effect upon our bodies without us even knowing anything about it.

Correspondingly, pharmaceutical opioids are not the only narcotics consumers can get their hands on. It is said that heroin, an illegal but natural opiate, “... scheduled 1 controlled substance in the United States…” (AmericanAddictionCenters) Taking heroin puts consumers at a high risk for addiction and abuse. Although heroin is a very dangerous drug it does dull pain, impair cognition and the senses, increase sedation, and slow functions of central nervous system. It is stated that “... heroin is the fastest-acting opiate.” (AmericanAddictionCenters). Heroin is described as a brown, or white powder or sticky substance that may be snorted, smoked, or injected, giving consumers a sense of “rush” or “high” that comes very rapid and very intense. Due to the fact that prescription opioids are becoming more expensive and less accessible many people turn to heroin, a much cheaper opiate. Not to mention, but three out four consumers who first started off by taking prescription medication who then became abusive of them now look towards the “high” of heroin. It's no coincidence that opioids, illegal or not can cause severe damage to the consumer that may even lead to deaths due to overdose. Above all, “heroin and other opioid drugs interact with the dopamine levels in the brain,which is what causes the burst of pleasure associated with their use.” (AmericanAddictionCenters) Clearly the abuse of any drug leads to drug tolerance, dependence, and last but foremost addiction.

The United States is currently in the midst of an Opioid overdose epidemic. Deaths from overdoses of prescription drugs continue to be the leading cause of unintentional death for Americans. Last year, 47,055 people died from drug overdoses - 1.5 times greater than the number killed in car crashes. Overdose is an excessive and very dangerous dose of a drug. Opioids are substances that act on opioid receptors to produce morphine-like effects. Medically, they are primarily used for pain relief. The most commonly prescribed opioid medications are Vicodin, OxyContin, and Percocet. Drug overdoses can be either accidental or intentional. They occur when a person takes more than the medically recommended dose. Treatments for overdose include medications

Additionally, opioid medications are the primary cause for overdose deaths in the United States. According to the Weekly Standard, “In 2014, the most recent year for which we have measurements, 47,055 Americans died from drug-induced deaths, with almost 29,000 dying from opioids…” (2), a figure that includes illicit synthetics, heroin, and prescriptions. From 2015 to 2016 in Maryland, fentanyl deaths rose by 268 percent and heroin deaths by sixty eight percent. Fentanyl has contributed to this dramatic increase in OD deaths because of its potency and lethality. It only takes two milligrams of fentanyl to kill a human. In fact, a single kilogram of fentanyl is capable of killing 500,000 people (Murray, Blake, and Walters 2). More than 30,000 opioid deaths occurred for the first time ever in 2015, which is 5,000 more than in 2014. Since the 1990s, heroin deaths had not surpassed prescription opioids (oxycodone and hydrocodone) until now. In 2007, gun homicides outnumbered heroin deaths at a rate of five to one, however at the height of the epidemic, now heroin OD deaths outnumber gun homicides (Ingraham 2). It is obvious that these unprecedented levels of drug deaths are derived from the opioid epidemic and need immediate attention.

A heroin overdose is generally a familiar, yet taboo, subject in today’s culture. It is familiar because one can witness the drug’s devastating effects like crime, imprisonment, and death within their community. It is taboo because it is culturally unacceptable and embarrassing to use an illegal product. Heroin overdoses have become a huge epidemic in Northwest Ohio, due in large part, to a misinformed culture, an influx of pain management programs, mixed drug toxicity, and a user’s desire to abuse laced heroin. With doctors, scientists, and researchers desperately searching for an answer to why heroin addiction is so prevalent, our community can find relief by being properly informed on

As the war on drugs continues, more and more lives are being lost to opiate overdoses. Opiates are drugs that contain or are derived from the opium poppy plant. They can be legally prescribed pain medications such as OxyContin or Vicodin or illegal street drugs such as heroin. Whether these drugs are used legally or illegally, there is always the chance of an overdose if not used correctly. According to a 2014 press release from the Center for Disease Control (CDC), “in 2013 more than 16,000 deaths in the United States involved prescription opioids, and more than 8,000 others were related to heroin.”

The author Margaret Talbot's is partly using her article about drug overdose to get these addicts help. In the early 90’s there was a large prescription rate of opioids. Patients with chronic pain issues were immediately prescribed intense and addictive drugs instead of looking for other options because most doctors did not know the underlying effect that the drugs would have. At the same time the pharmaceutical companies were promoting opioid pills quite aggressively. In 1996, Purdue Pharmaceuticals came up with a reformulation of oxycodone, which is one of the key opioids. Oxy was a release form drug, and it was supposed to be something that would last for 12 to 24 hours. Oxy was not supposed to lend itself to abuse, but it became a pill