There are many genetic disorders in the world. Some are obvious about what they do to a person’s body. While others are more subtle or completely unnoticeable from just looking at them. Some have severe side effects, while others do not. Genetic disorders affect people in that they affect sometimes many people, they can shorten one’s life expectancy, and it alters a person’s body and possibly their physical appearance. One genetic disorder that is more common, but still widely unknown, is hemophilia, a blood disorder. Hemophilia is a medical condition in which the ability of the blood to clot is severely reduced, causing the sufferer to bleed severely form even a slight injury. This causes people to bleed for long periods of time, since …show more content…
A hemophiliac’s extent of bleeding will depend on the severity of their hemophilia. One symptom of hemophilia is excessive bleeding. Bleeding is external and internal. According to the National Heart, Lung, and Blood Institute of the Institute of Health, “Signs of external bleeding may include: bleeding in the mouth from a cut or bite or from cutting or losing a tooth; nosebleeds for no obvious reason; heavy bleeding from a minor cut; bleeding from a cut that resumes after stopping for a short time”. They also say, “Signs of internal bleeding may include: blood in the urine (from bleeding in the kidneys or bladder); blood in the stool (from bleeding in the intestines or stomach); large bruises (from bleeding into the large muscles of the body”. Another thing this disease does to the body is it causes bleeding in the joints. This is another form of internal bleeding. Some joints included are the knees and elbows. The process of bleeding in the joints goes as follows; the joints are tight, but with no pain or visible signs of bleeding. Then, the joint becomes swollen, hot to the touch, and it is painful to bend. Bleeding and swelling both continue. Movement in the joint becomes temporarily lost. The pain can be severe. If this is not treated quickly, then the joint may be damaged. More internal bleeding includes bleeding in the brain. This is, as imagined, a very serious complication. It can
Hemophilia is an X-linked recessive disease in which blood lacks blood-clotting proteins. Females have two X chromosomes, indicating that they are generally carriers and transmit the gene to their sons. People with mild hemophilia bleed after surgery, injury, or trauma. Severe hemophilia produces spontaneous internal bleeding in joints and muscles. Fortunately, medicines and lifestyle changes offers hemophiliacs fairly normal lives. Through learning about hemophilia, I became interested in genetic diseases and finding a cure for those
The genetic disorder of Hemophilia is where the clotting factors of the blood are absent or deficient, causing it to be a dangerous disorder to the people who have it. This disorder is where the people who have it will bleed easily and accessibly. Different types of hemophilia are classified by different deficient clotting factors in the blood. Treatments for hemophilia are available, including transfusions of frozen
Hemophilia A is an X-linked disorder caused by a deficient or defective clotting factor VIII (FVIII) protein, and characterized by spontaneous or traumatic bleeding into joints and muscles [Ragni]. It causes afflicted individuals to not be able to coagulate their blood very efficiently or at all when getting an injury in which blood is exposed either internally or externally. This disease can be very dangerous and fatal because major blood loss can occur if the patient has not received treatment.
“Hemophilia (heem-o-FILL-ee-ah) is a rare bleeding disorder in which the blood doesn 't clot normally.” (NIH, 2013) Hemophilia is a chromosome – linked bleeding disorder caused by
As previously mentioned, hemophilia A varies in severity, which in turn includes symptoms (Iorio et al., 2010). Obviously the main symptom is excessive bleeding. Usually, hemophilia A is first noticed when an infant is circumcised (Iorio et al., 2010), however milder cases of hemophilia can be noticed later in life. If this is the case, mild cases can go unnoticed until after a surgery or injury in which internal bleeding would be a problem (Iorio et al., 2010). In addition, victims of hemophilia are recommended to get a hepatitis B vaccine due to the fact that they may receive blood products (Iorio et al.,
Hemophilia is a possible cause of unexpected bleeding during surgery. This paper will discuss important topics related to hemophilia, including pathology, risk factors, signs and symptoms, and treatment.
Hematoma formation may occur when there is bleeding in the muscles, which can be mild or severe, that includes muscle hardening, tenderness, pain, and swelling. Nosebleeds or slight bleeding from the mouth may occur in which they are common. After a visit at the dentist office, minor bleeding is common, young children may have a trickle of blood from the gums when new teeth are coming in. Blood in the stool are signs that there is blood in the gastrointestinal tract. Bleeding from the urinary tract can lead to blood in the urine which is called hematuria. Intracranial hemorrhage is when there is blood seeping through the brain, following a bump on the head, and can lead to certain symptoms like nausea, vomiting, behavioral changes, clumsiness, vision problems, paralysis, lethargy, and can lead to death. Another characteristic of hemophilia is increased bleeding after surgery or
Individuals with hemophilia may have a mild, moderate, or severe form, although the severe form is more prevalent. Individuals with hemophilia will bleed longer than others would. “Bleeds can occur internally, into joints and muscles, or externally, from minor cuts, dental procedures or trauma” (National Hemophilia Foundation, n.d., para. 7). Mild hemophiliacs may experience excessive bleeding only after a significant injury or procedure (National Hemophilia Foundation, n.d., para. 8). Individuals diagnosed with moderate hemophilia may experience bleeding episodes after both minor and serious injuries and have few spontaneous bleeds (National Hemophilia Foundation, n.d., para. 8). Severe hemophiliacs are prone to profuse bleeding after an injury and spontaneous bleeding episodes that appear to have no cause (National Hemophilia Foundation, n.d., para.
Hemarthroses are responsible for roughly 75 percent of bleeding episodes in patients with severe hemophilia A degree (Roberts et al, 2010). Signs of hemarthroses include damage to capillaries located under synovial layer caused by mechanical trauma related to joints involvement in the regular daily
You mentioned hemophilia so I just wanted to explain what it was. Hemophilia is an inherited disease that affects the clotting process of your blood. Therefore, if you have hemophilia you do stand a chance of sever bleeding if you incur an injury or cut. There is a protein that is called clotting factor that a person might have little or none at all. It is a protein used for blood clotting that helps blood platelets stick together. (NIH
Hemophilia is a rare disorder when blood doesn't clot normally because it is short on sufficient blood-clotting proteins. Deep bleeding inside the body is big concern especially in the knees, ankles and elbows. The internal bleeding caused from this can damage the organs and tissues of the body and may be life threating. When a person without Hemophilia is injured, a system of procedures happens to make the blood turn from liquid to solid to clot the wound and make the blood flow stop. Platelets, which are cells found in the blood, combine together to form a clot at the site of bleeding. The platelets hold an enzyme that causes fibrinogen to change to fibrin which is a solid substance that doesn’t liquefy. The fibrin goes to the area of injury
A. It 's important to know that hemophilia is not actually a disease or virus. https://my.clevelandclinic.org calls hemophilia "a rare hereditary (inherited) bleeding disorder in which blood cannot clot normally at the site of a wound or injury". This means that it is not contagious, rather it is passed down through genetics. When a hemophiliac gets injured,
Severe hemophiliacs can also have frequent nosebleeds, blood in their urine (bleeding in their kidney and bladder), and blood in their feces(from bleeding in their intestines and stomach).
Hemophilia is an inherited genetic bleeding disorder that occurs due to deficiency of plasma coagulation factors causing lifelong recurrent bleeding episodes into joints, muscles, and closed spaces either spontaneously or following an injury.
Hemophilia is a problem with the blood in a person that causes them to bleed not any faster than normal, but they often bleed for a longer period. Their blood is missing the clotting factor (a protein in the bloodstream that works to control bleeding). Hemophilia is quite rare; roughly 1 in every 10,000 persons are born with it. Rarely, hemophilia can be an acquired disease which just means a person is not born with it, but will develop it during their lifetime. This rarity occurs when a person's immune system forms antibodies that attack the clotting factor in the blood. The entire antibody population fights against the blood to prevent the clotting factors from working properly.