Midterm Paper: The Immortal Life of Henrietta Lacks On October 4, 1951 a 31 year old woman named Henrietta Lacks passed away after months of fighting aggressive Cervical cancer. Before her death, Henrietta’s doctors had taken a small sample of the Cervical tumor that had been slowly killing her and developed what would become known as the first “immortal” cell line. Without Henrietta or her family’s knowledge, researchers named the line “HeLa” and before long were distributing the constantly replicating cells across the globe to researchers studying anything from cancer to beauty care treatments. However, Henrietta was more than just some delivery vessel for an important cell line. She was a young, beautiful, and caring mother whose …show more content…
Originally diagnosed as an epidermoid carcinoma, her tumor was later found to have been an adenocarcinoma (an especially aggressive form of cancer). Unlike any other cells, HeLa cells did not need large surface areas of glass in order to grow and could even grow in suspension. It is now known that Henrietta’s cells had been infected with multiple copies of HPV-18 on her 11th chromosome which blocked the p53 tumor suppressing genes. To this day, however, no one completely understands why the HeLa line is so aggressive with its replication but the line’s fast replication and ability to grow easily has made it extremely valuable to researchers.
Dr. Gey, the man whose laboratory HeLa was first grown in, was a pioneer in the development of culture medium. He and other scientists knew that before any cell line could be grown and remain established outside of the body, a way to mimic the body 's environment and nutrients needed to be developed. At the time, no one knew which exact nutrients were needed by the cells. Determined to find a solution, Gey experimented with a variety of ingredients such as chicken plasma, special salts, and human umbilical blood. Although Gey was indeed a pioneer in cell culturing, the way in which he acquired human cells was ethically quite questionable.
Henrietta’s doctor, Dr. Jones, worked for a
“The Immortal Life of Henrietta Lacks” is a story of a woman named Henrietta Lacks, but many people refer to her as HeLa. Henrietta was the wife of David Lacks and a mother to her children. Henrietta noticed a knot on her cervix one day and became concerned. After a while Henrietta decided to seek medical attention. Henrietta got examined at John Hopkins hospital in Baltimore, which was when Henrietta was diagnosed with cervical cancer in 1951. Henrietta underwent many painful x-ray therapy and radium treatments to get rid of the cancer, during these treatments some tissue from Henrietta’s tumor was removed without informing her or her family. The tissue was taken to George Grey, who was John Hopkins head in the Tissue Culture
In 1951, the first immortal cell line was created by a doctor at Johns Hopkins Hospital using tissue samples taken from a young, black woman named Henrietta Lacks. Her cells would come to be known as HeLa cells, and for a very long time, the owner of these cells was a mystery; even her family did not know about them. For years to come, her cells would be used in many important medical and scientific advancements. Over that time, HeLa cells would prove to be instrumental in developing a polio vaccine, gene mapping, and in vitro fertilization. They would even be sent to space to see how cells would react in zero gravity.
Third, although the public health discovery of the HeLa cells improved the quality of life for many families/communities and the overall nation, it did not positively influence the quality of life of Henrietta Lacks or her family. Henrietta Lacks cells were not only taken from her body once and sent to unauthorized holders, but a second time after she passed away from cervical cancer. Neither Henrietta nor her family had given consent for Dr. Gey or the coroner to remove cells from her body and send them off for research
Finding discoveries that would greatly benefit medicine have always been difficult to achieve in cancer research. Though, everything changed on February 1, 1951, when Howard Jones discovered that Henrietta Lacks had cervical cancer. When George Gey heard of this, he took samples from Henrietta Lacks’ tumor, and found something that changed for future medical research. George Gey had noticed that Henrietta Lacks’ cancer cells was the first human cell line that could be consistently passaged. The cells were later called HeLa cells, which were named after Henrietta Lacks. Even though scientists greatly benefited from it, Henrietta Lacks, nor her family profited from it.
Due to the fact that Henrietta’s cells were the first human cells grown in a lab that did not die after a few cell divisions, they could be used for conducting many experiments. Her cells were considered “immortal”. This was a major breakthrough in medical and biological research. One major breakthrough was the development of a vaccine for polio. To test the vaccine the cells were quickly put into mass production in the first-ever cell production factory. Another enormous breakthrough was the successful cloning of human cells in 1955. Demand for the HeLa cells grew quickly. Since they were put into mass production, Henrietta’s cells have been mailed to scientists around the globe from “research into cancer, AIDS, the effects of radiation and toxic substances, gene mapping, and countless other scientific pursuits.” (Smith, 2002, "Wonder Woman: The Life, Death, and Life After Death of Henrietta Lacks, Unwitting Heroine of Modern Medical Science".) HeLa cells have been used to test human sensitivity to tape, glue, cosmetics, and many other products. Scientists have grown some 20 tons of her cells, and there are almost 11,000 patents involving HeLa cells. (Batts, 2010)
The non-fiction book The Immortal Life of Henrietta Lacks, written by Rebecca Skloot, details the happenings and life of Henrietta Lacks, an African American woman and tobacco farmer who became a medical miracle in the 1950’s. The book is written in an attempt to chronicle both the experiences and tribulations of Henrietta Lacks and her family, as well as the events that led to, and resulted from, research done on Henrietta Lacks’ cells. Henrietta was a very average African American woman in this period; she had only a seventh-grade level education, and followed traditional racial and gender roles by spending her time has a mother and caretaker, as well as working on farms throughout her life until the involvement of the US in World War II brought her and her husband, “Day” Lacks, comparatively better work opportunities in industrial steel mills. However, after her death in 1951 Henrietta became much more than average to doctors at John Hopkins when the discovered that cells extracted from her cancerous tissue continued to live and grow much longer than any other tissue samples. Further investigation and isolation of these thriving cells led to the creation of the first ever immortal human cell line in medical history. The incredible progress in medicine made possible by Henrietta Lack’s tissue cells were not without downfalls, though. The treatments and experiences received by Henrietta and the effects it had on her and her family demonstrate both racial and gender
The Immortal Life of Henrietta Lacks, by Rebecca Skloot, is the story of Rebecca’s journey in discovering the truth behind HeLa cells. HeLa cells are the first line of”immortal cells” grown in culture; scientists have tried to culture cells before, but the cells died within days of incubation, so HeLa cells were a revolution in the scientific world. With HeLa cells, scientists created vaccines for polio, tested nuclear radiation, and saw how cells reacted in space. Companies benefited when they produced HeLa cultures, and made millions. Although, not many people knew where HeLa cells came from or Henrietta Lacks, whose cells were cultivated without her consent and named HeLa, died of cancer without her
In addition to assigning HeLa cells human-like qualities, Skloot also attributes characteristics to them that transcend human life. Skloot describes the first time that HeLa cells were first cultured by stating, “Henrietta’s cells weren’t merely surviving, they were growing with mythological intensity” (40). “Mythological” in this statement is crucial because it is used to indicate that what it describes falls beyond human and scientific understanding. The word has its root in mythology, which typically describes ancient religious systems. For this reason, mythology and that which is “mythological” are associated with the divine in some regard, so this statement shows that there is something inherently spiritual and divine about the cells. It is important to note that Skloot does not directly describe the cells as “mythological” but the rate at which they grew. Through this language, she implies that HeLa cells have qualities that allow them to achieve feats beyond those of typical humans and cells, while still keeping HeLa confined to the scientific realm because they are not actually “mythological.”
Many people would assume that, because of HeLa’s impact on society, the Lacks family is probably very wealthy and well informed about HeLa cells; unfortunately, that is not the case. Not only did the Lacks feel taken advantage of by the medical community, but it wasn’t until an article by Howard Jones in December 1971 that Henrietta’s real name was finally revealed. That same article was used to inform Bobbette Lacks, Henrietta’s daughter-in-law, that the immortal cells she had been reading about in the paper were Henrietta’s. Bobbette was the first member of the Lacks family to learn about the fate of Henrietta’s cells and she immediately ran to the family yelling, “Part of your mother, it’s alive!”(181). The family felt misinformed, confused, betrayed and most of all, angry. In 1976, Mike Rodgers published an article in Rolling Stone that informed the Lacks family that people were buying and selling Henrietta’s cells. The family immediately accused Hopkins of withholding money from them. Lawrence, Henrietta’s eldest son, was quoted saying, “Hopkins say they gave them cells away, but they made millions! It’s not fair! She’s the most important person in the world and her family living in poverty. If our mother so important to
In her book, The Immortal Life of Henrietta Lacks, Rebecca Skloot discusses how one woman’s unfortunate diagnosis of cancer resulted in the discovery of the first immortal human cell line, HeLa. The establishment of the HeLa cell line has proven to be one of the most influential breakthroughs in the biomedical sciences because these cells have played a major role in some of the largest breakthroughs in since they were first cultured in the 1950s. In addition to an examination of the science behind HeLa cells, Skloot also provides a look at the lives of Henrietta Lacks’s descendants. One characteristic that all members of the family share is a dedication to religion and spirituality. This juxtaposition between science and religion presents the body and its constituent cells in a unique way. It provides multiple dimensions to how people can view bodies. Specifically, Skloot’s depiction of HeLa cells presents the body and its individual cellular components as entities that exist as both scientific and spiritual beings simultaneously.
In 1951, Henrietta Lacks was diagnosed with cervical cancer at John Hopkins Hospital. Without any consent, Henrietta’s doctors took tissue samples from her cervix and attempted to grow them and keep them alive. These cells, known as HeLa cells, began to grow at an unbelievable rate; The HeLa cell became vital for the development of vaccines and other scientific research. However because of Henrietta’s race and economic standpoint, Henrietta Lacks and the rest of the Lacks family was exploited by doctors. The exploitation of the family allowed the doctors and researchers to benefit scientifically and monetarily.
Within the novel The Immortal life of Henrietta Lacks written by Rebecca Skloot, the exponential growth of research due to the introduction of HeLa cells is exemplified through the vast scientific breakthroughs achieved. Before the presence of HeLa cells scientist had an endless amount of questions and theories but were unable to test their hypothesis due to lack of a perfect test subject. HeLa cells grew in almost every medium and most importantly, they grew fast. HeLa cells were especially useful when trying to study viruses, and the effects of certain antibiotics and other medicinal substances. Part 3 of The Immortal Life of Henrietta Lacks provides multiple instances where the use of HeLa cells was detrimental for medical research. One major use for Henrietta's cell was the medical
In February 2010, science writer and best seller author Rebecca Skloot published a book titled The Immortal Life of Henrietta Lacks, in which she captured the life story of Henrietta Lacks and the start of her immortal life. Skloot describes the life, death, and aftermath that Henrietta had during her treatment at Johns Hopkins Hospital, in the 1950s. For further research with Henrietta’s condition doctors needed to take tissue samples of her cervix. Unaware to Henrietta that this procedure was taking place without her consent. Skloot takes us on her journey as she tries to find the answers of Henrietta’s past and family. Beginning at Johns Hopkins Hospital, “colored ward” to the laboratories where researchers had freezers filled with HeLa cells, from Henrietta’s small hometown of Clover, Virginia to the East Baltimore, where her family and grandchildren strived and struggle with the issues of her cells (Skloots 34). Skloot tells a remarkable story of the creation of the HeLa cell while also highlighting the issue of bioethics and legal battles toward ownership of her cells.
The book The Immortal Life of Henrietta Lacks by Rebecca Skloot, was a nonfiction story about the life of Henrietta Lacks, who died of cervical cancer in 1951. Henrietta did not know that her doctor took a sample of her cancer cells a few months before she died. “Henrietta cells that called HeLa were the first immortal human cells ever grown in a laboratory” (Skloot 22). In fact, the cells from her cervix are the most important advances in medical research. Rebecca was interested to write this story because she was anxious with the story of HeLa cells. When she was in biology class, her professor named Donald Defler gave a lecture about cells. Defler tells the story about Henrietta Lacks and HeLa cells. However, the professor ended his
For our group activity, we decided to see the Immortal Life of Henrietta Lacks film on Monday, October second. Intercultural Affairs hosted the film as a part of the One Book selection for the year. It was both an eye-opening and enjoyable experience. We all looked forward to attending the event, and after we all agreed that it was very well put together.