Tracking the Ebola Virus

In his book, The Hot Zone, Richard Preston focuses on an outbreak of the Ebola virus in Reston, Virginia and in multiple places in Africa. To show how dangerous an outbreak can be, Preston examines, in great detail, various other viral outbreaks, including Marburg. Preston begins by talking about a fifty-six year old Frenchman named Charles Monet who ends up breaking out with a treacherous disease called Marburg. This wasn’t known until his doctor, Dr. Shem Musoke, ended up testing positive for Marburg after Monet`s infected blood went all over Doctor Musoke as Monet was dying. Musoke survived his outbreak with Marburg.

It is vital to understand deadly viruses and their history in order to prevent future outbreaks. Ebola leaves very few clues after annihilating its victims, so it is incredibly important to analyze those clues. Ebola’s close relationship to monkeys contains key knowledge that could hold the secret to its success. Paying close attention to how Ebola is spreading and mutating could lead researchers to the answer for preventing the contraction of it. Discovering where and how the virus first emerged could lead to Ebola’s end.

Although Ebola was first reported in 1976, little news was released on the outbreaks which had occurred in Sudan and Zaire and which had taken away the lives of 434 people. Then in 1989 there was the Reston incident, where monkeys shipped to the United States from the Philippines, died in large numbers due to what is now known as Ebola Reston, and the virus killed all monkeys. Fortunately that particular strain was not found to be deadly to humans. For now, the Ebola virus appears again and causes large damage in Africa. The horrible disease failed to appeal to those media institution which results in the information interruption, the public do not have an access to the newly information concerning Ebola. The study on the relationship between

Ebola is described by the author in deep detail telling the progression of which it goes through. It starts with a headache and backache and ends with all of your internal organs failing “bleeding out” like Charles Monet. There are four filoviruses: Ebola virus (EBOV), Sudan virus (SUDV), Marburg virus (MARV), and Ravn virus (RAVV). They are all Level 4 biohazard, which means they are extremely dangerous to humans especially because they are so infectious, have a high death rate, and there are no medicines, treatments, or cures.

Starting with one of the four filoviruses mentioned in the book, Preston provided us with the story of Charles Monet, an amateur French naturalist who died a gruesome death after contracting Marburg virus following a trip to Mount Elgon. Marburg is brought up in the story several times as a close relative of Ebola, having similar symptoms and equal danger. Throughout the next several chapters, different strains of Ebola are reviewed; the Sudan

Several years later, the author visits with Dr. David Silverstein, who has gained a huge reputation in Nairobi. Silverstein relates a 2 a.m. phone call that informed him that Dr. Musoke's blood tested positive for Marburg, a virus about which little is known. It was named after a town in Germany where, in 1967, citizens contracted the virus from monkeys transported from Uganda to a local laboratory. Many of the monkeys had been brought in by a trader who was more interested in money than the health of the animals.

Ebola was first recognized in 1976 as the cause of outbreaks of disease in the Democratic Republic of the Congo (then known as Zaire) and in Sudan. About three hundred people in each of the two nations were infected with the virus, resulting in a mortality rate of 88% in Zaire, and 53% in Sudan (Bulletin of the WHO 1978). The disease as it was discovered spread through direct contact of unmans to humans, and then thought, from non-human primates to humans. The epidemic was a result of unsafe and unsanitary hospital practices, and non-sterilized medical equipment. The disease was then contained, however sporadic outbreaks of the Zaire and Sudan Ebola subtypes have risen in the Democratic Republic of the Congo, Gabon, Uganda, and Sudan; one of the latest outbreaks was in the Democratic Republic of the Congo in September of 2007.

As with any infectious disease, whether it originates from a virus, bacterium, or fungi, there is the possibility that it will become an epidemic. For centuries, deadly diseases have threatened to infect and possibly eradicate mankind. The Ebola virus, which causes an extremely fatal hemorrhagic fever, is considered to be one of the most aggressive contagions in the world. The Ebola virus is a member of a family of RNA viruses known as, “Filoviridae” and is composed of multiple distinct subspecies (Bausch et al. 2007). It causes Ebola Virus Disease, a fairly new disease that plagues multiple poor countries within Africa. The virus mainly attacks the lymphatic system, but also severely damages the reproductive and reticuloendothelial systems. The Ebola virus disease causes muscle pain, weakness, limited kidney and liver function and extreme blood loss due to failure of blood clotting.

This book took place in the late 1980's, and it is based upon an outbreak of the Ebola virus in a monkey house located in the Washington, D.C. suburb of Reston, Virginia. The first occurrence of an Ebola-like virus (Marburg) takes place in Kenya and a French expatriate named Charles Monet is the first to die from this disease. His terrible and excruciatingly fatal death is described in the most horrific details by Preston. The hospital staff who treated Monet became infected with the virus as well, traveling fast throughout the hospital and carried on more deaths. The Marburg virus was first to explode in a vaccine factory in Germany in 1967. Over the next several chapters, the book describes outbreaks that occurred four years before Monet’s death. Preston then goes on to explaining how

This Ebola outbreak taught us many factors of public health that we simply ignore daily, like washing hands. These viruses are easily transmitted from person to person, through their blood or body-fluids. Therefore it is very important to research about our public health around us, for everyone’s health and future. The Ebola outbreak showed how the world is very ignorant of their public health. It is better for them to know all of these tragedies and educate themselve to prevent from any other outbreaks that will take place in the future. The plan to release more information and persuade to adjust West African culture will definitely make public healthier, view the world differently, and our future generations will learn the importance of learning

got sick and died. This outbreak infected 318 with a death rate of 93% (Le

The fight for who can proceed in experiments to find the cure for Ebola is on. In the experiments done by the lab scientists from, Therapeutic Intervention of Ebola Virus Infection in Rhesus Macaques with the MB-003 Monoclonal Antibody Cocktail persisted in a slight solution that resulted a minor success, but a success that is well needed. On the other hand, Dr. Lipstich feels that the results may not be so worth it considering that high risk of the scientists themselves catching the deadly virus. The virus held in its early stages in West Africa, where the first host was a little boy that had died in pain. From then the virus spread abruptly from one host to another. As American scientists try to search for the cure in other diseases such as fatal fibrosis, they realized once the damage was done that there was a deadlier, possibly airborne

Dangerous diseases constantly appear in the news. Currently, Zika virus is causing a demand for action to protect the general public. Due to the public outcry, President Obama has decided to ask Congress for money to fight against Zika virus. To analyze this within the context of political science, two things must be understood. First, understanding the broader sense of why the president needs to ask Congress for funding. Second, is to understand what happened when the president asked Congress for money to fight other diseases, like Ebola.

Responses to the Ebola outbreak show that the international community has yet to reach agreement on what constitutes an adequate policy response to transnational public health crises. Currently, governments are continuing to use isolation and quarantine to protect against contagious diseases. Also, they are implementing effective legally binding agreements such as the International Health Regulations which tend to improve 196 countries to respond to global public health threats. However, these measures are not sufficient against future health crises. The challenge is to change structures of power including neoliberalism, capitalism, and racism at all levels of politics and policy, which something that is largely absent from the conventional

In the year 1967 a disease called the Marburg virus (MVD), formerly known as Marburg hemorrhagic fever, was discovered. MVD was identified during epidemics in Marburg and Frankfurt in Germany and in Belgrade in the former Yugoslavia (now Serbia) from importation of infected African green monkeys from Uganda. Thirty-one people became sick, first the laboratory staff, followed by several family members and medical personnel who took care of the ill laboratory workers. Seven deaths were reported. The very first people infected were researching the imported African Green monkeys or the tissue of the monkeys while conducting research.