1. Introduction 1.1 A brief overview of Alzheimer’s diseases The life expectancy is now doubled from the last century in the developed countries due to the revolution progress in medicine and health mainly to chronic diseases. Alzheimer’s disease (AD) is one of the most well-known and familiar diseases in the modern societies AD was first reported by Alois Alzheimer in 1907.The AD is the most common type of dementia and a neurodegenerative disease characterized by the damage of nerve cells in the cerebral cortex. The health statistics report that AD disease affects more than 50 million people worldwide in 2003, it is expected this number to increase to 114 million by 2050.(1) It is reported that AD disease affect one in three people over the age 85.(2) The symptoms of AD include depression, apathy, anxiety, agitation, aggression, delusions, hallucinations, wandering, and inappropriate sexual behaviours.(3) AD patients suffer from decrease in cognitive function and short term memory. AD is characterised by the formation of insoluble clumps of protein or plaques, formed by proteins known as β-amyloids. These attach to the cell surface of neurons and disabled nerve transmission. These plaques have been demonstrated to contain relatively high levels of Zn2+, Cu2+ and Fe3+ (1 mM, 0.4 mM and 1 mM respectively).(4) While the precise role of these metals is still uncertain, they appear to bind to so-called β-amyloid peptides that constitute the bulk of plaque deposits. Cu2+
Alzheimer’s disease is the 6th leading cause of death in America. It kills more than breast cancer and prostate cancer combined. Alzheimer’s accounts for 70-80% of dementia cases. By the age of 65, 1 in 9 people are diagnosed and by the age of 85, 1 in 3 people will have the disease. According to the Alzheimer Association, 5 million people in American have Alzheimer’s. Alzheimer’s starts to form 20 years prior to being diagnosed. Learning about Alzheimer’s can help families understand how Alzheimer’s is more than just memory loss, it is an incurable mental disease.
Alzheimer 's disease (AD) is a progressive degenerative disease of the brain from which there is no recovery. There are three brain abnormalities that are the hallmarks of the Alzheimer’s disease is initially caused by plaques buildup in the brain’s neurons as illustrated in figure 1. The support structure that allows the flow of the nutrients through the neurons gets damaged and ultimately there is loss of connection among the neurons and they die off (National Institute of Health, 2015). This causes the brain tissue to shrinks, which is called atrophies. All this ultimately lead the victim of this disease to face difficulties in governing emotions, recognize errors and patterns, coordinate movement, and remember. Ultimately, a person with AD loses all memory and mental functioning.
The disease stem cells could fix is called Alzheimer’s Disease (AD). The reason I chose this topic is because I have seen first hand how badly someone who suffers from Alzheimer’s Disease is affected in their daily lives. This disease completely takes over their lives and they turn into a completely different person who can hardly function. AD is very tough on the loved ones of the person suffering from it because that person, most of the time has no idea what is going on or who their loved ones are. The memories for people with AD is completely gone and even the simplest tasks such as remembering to use the bathroom becomes difficult. The way stem cells could be feasible is because stem cell-based therapies could potentially treat
Alzheimer’s is a disease in the brain that affects a person’s memory, thinking, and behavior. It is the most common form of dementia and is common in adults older than 65. More than five million Americans are being affected by Alzheimer’s at this moment. Alzheimer’s comes in three stages; early, middle, and advanced. The disease is caused by the shrinking of the brain due to many risk factors and genetics.
Alzheimer's disease is one of the most common causes of dementia. The term 'dementia' describes a set of symptoms, which can include memory loss, changes in mood and problems with communication and reasoning. These symptoms occur when certain diseases and conditions, including Alzheimer’s disease, damage the brain. Alzheimer's disease could be described as a physical disease affecting the brain. During the course of the disease, protein 'plaques' and 'tangles' develop
Alzheimer’s Disease has been one of the top leading causes of death in our country. It is understood that this disease is identified as an excess of the protein amyloid-ß within an increase of plaque (Seneff, Wainwright, and Mascitelli, 2010). Additionally, as the brain ages, it gets used to the inflammation and oxidative stress, so it is important to take the right amount of antioxidant micronutrients like vitamin C and vitamin E as well as anti-inflammatory macronutrients such as omega-3 polyunsaturated fatty acids to protect the brain from ageing (Whalley et. al, 2004). This is a devastating disease that affects most people over the age of fifty. Recently, there have been many studies done to figure out what causes this disease, if there is anything that can cure it, and how to prevent the disease. Seneff, Wainwright, and Mascitelli, believe Alzheimer’s develops with consuming too many carbohydrates, especially fructose and having a deficiency in cholesterol and dietary fats as well (2010). Whalley, Starr, and Deary have seen that poor diet, poverty, and failing health are links to developing Alzheimer’s Disease (2004). Furthermore, seeing increase in plasma homocysteine concentration increases risk of Dementia, which can result from an inadequate intake of vitamin B12/folate (Walley et. al, 2004). Additionally, Gray supports Walley’s findings and even believes having an adequate intake of vitamin B12/folate will have a positive effect on the overall health
Alzheimer’s disease is a prominent brain disease that effects a massive amount of individuals in the United States. Alzheimer’s disease (AD) is the sixth leading cause of death in the United States, accounting for 60-80% of dementia cases, with no chance of being cured, prevented or decelerating over time (Alzheimer’s Association, 2014). AD is the most well-known form of dementia, causing complications in brain function in the areas of memory, thinking, and behavior (Alzheimer’s Association, 2014). In an effort to gain a deeper understanding of Alzheimer’s disease, researchers create new knowledge about the disease, which is then distributed to the public. The goal in this information disbursement is to find new and inventive ways to treat AD, prevent AD from progressing at such a rapid pace, and aid in the quality of life in those diagnosed with AD as well as caregivers and medical professionals providing treatment to individuals’ with AD.
It occasionally happens to everyone. You can’t find your glasses. The grocery list is on the refrigerator, and you’re at the store. You forget the new neighbour’s first name.
“There is one thing Alzheimer 's cannot take away, and that is love. Love is not a memory - it 's a feeling that resides in your heart and soul.” (Fade to Blank). The human brain is a remarkably complex organ that processes, stores, and recalls information. “Alzheimer 's disease (AD) is a slowly progressive disease of the brain that is characterized by impairment of memory and eventually by disturbances in reasoning, planning, language, and perception. Many scientists believe that Alzheimer 's disease results from an increase in the production or accumulation of a specific protein (beta-amyloid protein) in the brain that leads to nerve cell death.” (Crystal). It is the most common form of dementia, accounting for 50 to 80 percent of dementia cases, and currently has no cure. (# 3) Research continues to be done to develop better ways to care for those affected with the disease, as well as to find support for family members, friends, and caregivers. Alzheimer’s is a devastating illness that is not a normal part of aging. In order to find a cure, awareness needs to increase to improve understanding, develop effective treatments, and to essentially prevent the disease.
A brain deteriorates, slowly being engulfed by a mysterious disease. The neurons being cut off and destroyed by two abnormal structures. First memory is affected gradually getting worse. Then one is unable to think properly, reason, and lacks of self control. Gaps are formed in the brain 's ventricles, due to the amount of dead tissue. In the end, it will lead to death. All of this may sound like something from a science fiction movie but infact its very real. These are all known possible symptoms of a common disease that affects about millions of Americans. It is known as Alzheimer 's disease (AD), and I plan on explaining it a bit more in this paper. First I will explain the disease and list some facts about it,then I will talk about some commonly asked questions about it.
In chapter 15 I found the part on Alzheimer’s disease very informative and interesting. Alzheimer’s and dementia are diseases that I find great interest in. My paternal grandfather was diagnosed with Parkinson’s disease when he was just over the age of 60. He proceeded to be diagnosed with Parkinson’s induced dementia, and then he later passed away from the disease. My maternal grandfather suffered from a severe stroke about 4 years ago, and is now suffering from stroke induced dementia. Seeing anyone who is suffering from Alzheimer’s and dementia of some sort is very sad. I work in an assisted living facility and we have a specialized facility of people who are diagnosed with Alzheimer’s or dementia. Working with these people on a daily basis
The words moved into her mind, like leaves on an autumn breeze. She awoke to find the phone between her cheek and the pillow, the insistent buzzing the only sound from the black receiver. Had there been a voice on the line? Or had she only dreamed it? Or was she even hallucinating? She had had dreams before, but the kind that would wake her like an alarm bell. Heart pounding, pulse racing, it would take her several moments to get her to know where she was and that she had been dreaming.
Alzheimer’s disease is the most common type of dementia in the United States, with its commonness expected to increase dramatically in the coming decades. Although awareness of Alzheimer's disease has increased greatly among professional and amateur audiences, exact means do not exist to calculate how many Americans the disease affects. However, it is estimated that there are over 5.1 million people aged 65 or older with probable Alzheimer's disease. Alzheimer’s is also the sixth leading cause of death in America. Throughout, I will be addressing the issues that surround this disease: it is not an inevitable consequence of aging, the care and treatment, and end-of-life decisions. While explaining these issues, the goal is to achieve a better
Psychology is an applied as well as an academic field that studies both the human mind and behavior. The research in psychology attempts to explain and understand behavior, emotion and thought. The subject of psychology was created when Wilhelm Wundt opened up the very first psychology lab in Leipzig, Germany. Wilhelm Wundt believed that individuals who are appropriately trained would most likely be able to recognize the mental processes that are accompanied with feelings, thoughts and sensations (Wagner , 2009).
Although Alzheimer’s disease (henceforth: AD) has been around since the 19th century or possibly even earlier and was at a point in time classified as senile dementia, it wasn’t until 1906 following Dr. Alois Alzheimer’s encounter with Auguste Deter at a Frankfurt asylum that the name of the disease was finally coined. Since then, major developments relating to the disease has taken place. In our report, we addressed some of the areas of the history, contemporary and prospects of the disease.