A Short Note On Opioid And Opioid Analgesics

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Medication Medications commonly used are combination of non-opioid and opioid analgesics because most of the clinical manifestations revolve around managing the symptoms and preventing further prognosis of the disease rather than curing the disease. These medications listed below are commonly used pharmacological medications (Nadine Matthie, 2015). Generic name: acetaminophen, trade name: Tylenol. Acetaminophen is an antipyretic, and nonopioid analgesic used as pain reliever. It suppresses the synthesis of prostaglandins which controls the pain and fever receptors primarily in CNS (Vallerand & Deglin, 2017). Common side effects are, increase agitation in children, hypertension, hypotension. Acetaminophen is known as “safest…show more content…
This is used for opioid agonists and used as an antitussive also. Hydromorphone decreases in moderate to server pain by biding to opiate receptors in the CNS (Vallerand & Deglin, 2017). Common side effects are, confusion, sedation, hypotension, constipation, and respiratory depression can be a life-threatening. Administer this medication with extreme caution with MAO inhibitors as it may have severe and unpredictable outcome. Also, repaid administration may increase incidence of respiratory depression, hypotension, and circulatory collapse (Vallerand & Deglin, 2017). Generic name: oxycodone, trade name: OxyContin or Oxaydo. Oxycodone is another opioid analgesics and opioid agonist/non-opioid analgesic combinations. Oxycodone decrease pain by binding to opiate receptors in the CNS (Vallerand & Deglin, 2017). Common side effects are, confusion, sedation, constipation, and respiratory depression is a life-threatening side effect. If oxycodone is used with MAO inhibitors, it is recommended to decrease the initial dose by 25% as it may cause unpredictable reaction (Vallerand & Deglin, 2017). Nonopioid analgesic such as ibuprofen and acetaminophen also used to assist in managing the acute pain. As mentioned above, hydroxyurea, brand name: Hydrea have a highly effective outcome of reducing levels of HgS and have fewer painful episodes of sickle cell crisis (Smeltzer, Bare, Hinkle, & Cheever, 2010). More common side effects of hydroxyurea
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