Addison 's Disease : An Autoimmune Disorder Of The Endocrine System Essay

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Addison’s disease is an autoimmune disorder of the endocrine system. It is a hormonal insufficiency of adrenocortical due to the dysfunction of the adrenal glands. It effects men and women of all ages and races. Delay in diagnosis or treatment can be life-threatening. Treatment requires life-long hormone replacement therapy. Addison’s is predominantly found in Western countries then developing ones though it is unknown if individuals are more resilient or are dying undiagnosed. Higher education worldwide about this disorder could improve diagnosis and ultimately save lives.

Addison’s Disease
Addison’s disease was first detected by Thomas Addison in 1855, it is a disorder caused by insufficient levels of hormones produced by the adrenal glands such as adrenocortical. It is caused by damage or dysfunction of the whole adrenal cortex and can be referred to as adrenal insufficiency. This failure to produce adequate hormone levels results in the body attacking itself known as an autoimmune disorder. It occurs in both men and women at any age and has no racial preference. Addison’s is predominantly seen more in Western countries than developing ones. Although it is not known if it is less common in these areas or if people are dying undiagnosed. This concern was the topic of the journal review, Diagnosis and Management of Addison’s Disease. This article focused on Addison’s in South Africa.
Deficiency in glucocorticoid (hydrocortisone), mineralocorticoid (aldosterone)
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