There are many known diseases in the world that we live in today affecting a wide range of individuals of different ages, ethnicities, and genders. With each type of disease comes a diagnosis, prognosis, and potential for a cure from one of life’s many ailments. Over the course of time, technology has began to lead the way in discovering as well as treating many disease in which doctors previously knew little about. Amyotrophic lateral sclerosis (ALS), often referred to as Lou Gehrig’s disease, was first described in 1869 by French neurologist Jean-Martin Charcot. In 1939 ALS brought international attention when Lou Gehrig abruptly retired from baseball after being diagnosed with the disease(6). Today there are as many as 20,000 …show more content…
Once motor neurons die, the brain has an inability to initiate impulses and control muscle movement of the body. Over the course of time as connections between muscles and nerves are damage muscles will gradually become weaker, twitch, and atrophy. There are many symptoms during the onset of ALS that are often overlooked that can include: Twitching, cramping, muscle stiffness or weakness, slurred and or nasal speech, or difficulty chewing or swallowing. Each patients symptoms vary depending on what muscles are damage first. Individuals can initially have the lower extremities affected or the upper extremities as well as noticeable speech problems. Damage to upper motor neurons can cause spastic muscles and contributes to an increase in reflexes, such as the gag reflex(7). Muscles may become weaker, however, patients are still able to perform voluntary muscle contractions with sensation still intact. Lower motor neuron damage is linked to muscles weakness, atrophy, cramps, twitching, and a decline of reflexes(BOOK). As the disease progresses throughout the patients body, they have increasing problems with muscle movement, maintaining weight, speaking, and swallowing. As muscles of the respiratory system weaken, patients also have difficulty breathing on their own and must depend on a ventilator
Have you ever heard of ALS, better known as Lou Gehrig’s disease? For many people, ALS is a disorder that they may not know much about. I never heard of it either until my father was diagnosed with this disease in 2006. Because there is no known cure, it is important to detect this disease early, so that proper treatments and preparation can be done before it’s too late.
Following the diagnosis of ALS the main goal of treatment is focused at relieving the symptoms. The most important matter in managing ALS patients is that they continually sustain the highest amount of movement and activity as possible and remain comfortable while doing so. Although a cure for ALS has not yet been developed, effective treatments do exist to assist the patients in their fight with the disease. Physicians urge the patients to carry on with their everyday lives doing all the activities and physically exerting themselves as they would normally do. But, they also recommend the patients to limit their amount of physical exertion
In addition, people need to know the symptoms of ALS. In ALS, there is deterioration to a point that all movement, including breathing, stops. Muscle weakness first develops in the muscles, such as the hands, and spreads through other muscles closer to the brain. Such early symptoms as this can hardly be noticed. Early symptoms of ALS are very slight and often overlooked. They begin as simple things such as tripping or dropping things. Twitching or cramping of muscles and fatigue of the arms and legs may soon follow causing difficulty in daily activities such as walking or dressing (ALS Association). In more advanced stages shortness of breath or difficulty in breathing and swallowing show until the body is completely taken over by the disease. Intellect, eye motion, bladder function, and sensation are the only abilities left unharmed by the disease. There are many symptoms for ALS and if any of these symptoms are noticed, that person could have ALS.
ALS is usually described as a neurological disorder that weakens your muscles. In other words, your nerve cells begin to die and you lose voluntary muscle control. It affects every person differently, but it most commonly appears in your upper core
The article titled “The Voices of A.L.S. by Tara Parker-Pope has given me a better insight into A.L.S. In fact, it has made me more aware of it. Amyotrophic lateral sclerosis (ALS) also known as Lou Gehrig's disease, affects parts of the nervous system that control voluntary muscle movement. Motor neurons, among the largest of all nerve cells, reach from the brain to the spinal cord and from the spinal cord to muscles throughout the body. When these motor neurons die, the brain can no longer start and control muscle movement. At this time there is no cure for the disease; however, over the past few decades, we have made amazing strides in our understanding of the brain, the nervous system, and genetics. Discoveries in each of these areas bring
ALS, otherwise known as Lou Gehrig’s disease, is a disease that attacks the muscles and impacts a person’s physical function. Overtime, the symptoms will
Amyotrophic Lateral Sclerosis (ALS) is a terminal disease, also known as Motor Neurons Disease, Charchot Disease and Lou Gehrig disease. ALS destroys the Central Nervous System (CNS) and causes damage to the upper and lower motor neurons in the brain. Signs and symptoms are characterized as: muscles weakness, muscle atrophy, twitching and reduced muscle reflexes. Eventually the patient will become paralyzed and rely on a tracheostomy and ventilator for breathing (ALS Association [ALSA], 2010).
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a terminal disease that degenerates the nerves in the brain and spinal cord. Motor neurons run from the brain, through the spinal cord, and into the muscles of person; this is what allows a person to have control over voluntary movement. When an individual is diagnosed with ALS, their motor neurons begin to degenerate, thus eradicating their ability to walk, eat, and eventually breathe.
Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease, is a neurological disorder that involves the degeneration of motor neurons. Commonly, ALS is referred to as “Lou Grieg’s disease” after the New York Yankee Hall-of-Famer, who was diagnosed with the disease in 1939 (mayo Clinic, 2010). According to the national institute of neurological disorders, ALS is a rapidly developing, consistently progressive, invariably fatal neurological disease that’s attacking the nerve cells needed for controlling voluntary muscles, or movement.” (NINDS, 2010). The muscles go through atrophy, which means the muscles gradually weaken and wasting away. Furthermore, ALS affects the neuromuscular system, which “enables our bodies to move
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease, which means there’s an increasing loss of neuron structure and function as the disease progresses. This is when there’s an unusual hardening of body tissue due to a lack of muscle nourishment and poor nerve cell transmission. ALS typically affects the ages of 40-70 years old, and for some unknown reason, military veterans are almost double the chance of developing ALS in comparison to the general public. The first large-scale effort to track ALS and its outcomes is the ALS CARE Database, where it stated that, of the people in the database, 60% were men, and 93% were Caucasian (Amyotrophic Lateral Sclerosis (ALS) Fact Sheet, 2016). There are 2 main types of ALS; sporadic and
Over time, ALS tends to lead to almost total paralysis of the muscle movements, and then it eventually leads to respiratory failure. The cause of ALS is unknown; however, genetics may play a role. If you have family members with ALS, have been in the military, or have certain genetic
Amyotrophic Lateral Sclerosis, also known as ALS or sometimes called Lou Gehrig’s Disease, is a progressive neurological disease affecting the nerves that control voluntary muscle movement. It is the most common type of motor neuron disease. The body isn’t able to operate as it normally does due to the muscles weakening overtime. As the disease progresses, it starts to damage nerves of other vital areas of the body. When the body isn’t able to breath the way it should causing respiratory failure and other things start to go wrong, the body has no choice, but to shut down and die. (ALS Association)
ALS is named for its underlying pathophysiology, which is “amyotrophy” referring to the atrophy of muscles fibers, which denervated as their corresponding anterior horn cells degenerate. “Lateral sclerosis” refers to the changes seen in lateral columns of the spinal cord as upper motor neuron axons in these areas degenerate and are replaced by fibrous astrocytes. ALS affects motor neurons at two or more levels of the motor neuron network supplying multiple regions of the body and as a consequence, the communication between the neurons and muscle is lost, promoting progressive muscle weakening. That is, ALS affects lower motor neurons that reside in the anterior horn of the spinal cord and in the brain stem, corticospinal upper motor neuron
The manifestations of ALS are caused by the location of motor neuron death. When upper motor neurons die, the symptoms include problems controlling fine movements, spasms, dysphagia, dysphonia and dysarthria (Porth & Matfin, 2009). “Manifestations of lower motor neuron destruction include fasciculations, weakness, muscle atrophy, and hyporeflexia” (Porth & Matfin, 2009, p. 1284). Patients with early signs of ALS usually complain of feeling weak on one side, which is due to the slowing of electrical impulses to that group of muscles (Ignatavicius & Workman, 2010). Since the impulses are slowed, they are not receiving adequate electrical stimulation to move and the person feels weak. As the disease progresses, all the motor neurons die and are not regenerated so, the patient is left paralyzed, losing the ability to speak, swallow and breathe (Ignatavicius & Workman, 2010).
Regardless of which occur first, affected individuals will generally experience most of the symptoms as the disease progresses. Specifically, symptoms that include difficulty swallowing, moving, forming words, tight muscles, spasticity, and/or exaggerated reflexes occur when the upper motor neurons have been damaged. When lower motor neurons are damaged, symptoms such as muscle weakness, atrophy, cramping, and twitching will occur. In some cases, a few of the muscle neurons that