Lou Gehrig's Disease: Amyotrophic Lateral Sclerosis

Decent Essays
Imagine you are a 78-year-old man, a beloved professor from Brandeis University. Every day you take notice of the increased difficulty of breathing, more so than the usual, or the out-of-breath feeling from climbing a flight of stairs. About two or three weeks later, you start to feel the muscles in your body cramping up, even while partaking in slight activity, And then you know it’s serious after you gave up dancing. After multiple testing, your results come back and you have ALS, also known as Amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease, is a neurological disorder that involves the degeneration of motor neurons. Commonly, ALS is referred to as “Lou Grieg’s disease” after the New York Yankee Hall-of-Famer, who was diagnosed with the disease in 1939 (mayo Clinic, 2010). According to the national institute of neurological disorders, ALS is a rapidly developing, consistently progressive, invariably fatal neurological disease that’s attacking the nerve cells needed for controlling voluntary muscles, or movement.” (NINDS, 2010). The muscles go through atrophy, which means the muscles gradually weaken and wasting away. Furthermore, ALS affects the neuromuscular system, which “enables our bodies to move…show more content…
Gene mutations prevent the breakdown of toxic substances leading to their buildup in nerve cells, which eventually is cell death. (Genetics Home Reference, 2012) Other causes are disorganized immune responses, protein mishandling, and lead exposure. A disorganized immune response may trigger the ALS process because of the proteins in cells, which causes cell death of nerves. In the same fashion, Protein mishandlings can lead to the steady amassing of irregular proteins, causing cell death. Additionally evidence suggests that lead exposure can lead the progression of
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