Analyzing Graves Disease

Graves ' disease is an immune system disorder that results in the overproduction of thyroid hormones (hyperthyroidism). The thyroid gland is an important organ of the endocrine system. The gland is located at the front of the neck above where the collarbones meet. This gland releases the hormones thyroxine (T4) and triiodothyronine (T3), which control body metabolism. Controlling metabolism is important for regulating mood, weight, and mental and physical energy levels. When the body makes too much thyroid hormone, the condition is called hyperthyroidism. Graves disease is the most common cause of hyperthyroidism and is most common in women over age 20. But the disorder can occur at any age and can affect men as well. Some of the symptoms of Graves diseases are

Experts aren’t sure the exact cause of Graves’ disease because it is an autoimmune disease. There are certain risk factors associated with Graves’ disease which include genetics, gender, age, pregnancy, mental stress, and smoking. People who have family history of this disease are more likely to develop it. Also females are more likely than males to acquire Graves’ disease and onset of the disease usually occurs after the age of 20. Anatomy affected by this disease is the thyroid gland which is part of the endocrine system. It is located at the back of the neck, below the Adam’s apple. This disease doesn’t destroy the thyroid gland, instead an antibody called thyrotropin receptor antibody makes the thyroid produce large amounts of hormone. The thyroid produces two hormones, thyroxine and triiodothyronine. These hormones affect many body systems and play a key role in regulating the body’s metabolic rate. Excessive secretion of these hormones is what causes the signs and symptoms that have already been described.

Week 3 – LOM Assignment The thyroid is responsible for taking iodine and converting it into thyroid hormones which are released into the blood stream and transported throughout the body where they control metabolism.1 The thyroid is a vital part of the human body as every cell in the body depends on it for metabolic regulation. Too much or too little thyroid hormone secretion can result in hyperthyroidism or hypothyroidism. Hyperthyroidism is caused when the thyroid secretes too many thyroid hormones. Hyperthyroidism causes a rapid heart rate, elevated blood pressure and tremors. Other symptoms include increased nervousness, inability to concentrate, weakness, restlessness, difficulty sleeping, frequent bowel movements, weight loss and irregular

However Graves' disease is named after the Irish physician who described several cases in London Medical Journal in 1835. Graves' disease is also known as Parry's disease. In Europe, the disease is known as Basedow's disease. It is the most common cause of thyrotoxicosis (the morbid condition due to over activity of the thyroid gland).

Graves’ disease is autoimmune that effects the thyroid in front of the neck. This thyroid creates T3 and T4 which helps regulate how the body uses energy. We have a small gland called pituitary in the brain that helps the thyroid regulate the hormone level properly. With grave’s disease the immune system creates antibodies that act like TSH (thyroid stimulating hormone) which than makes the thyroid to create more hormones than what the body needs to have. This is called hyperthyroidism. Graves’ disease causes the body to speed up such as the heart and the metabolism. The symptoms for graves’ disease are goiter (enlarged gland) Anxiety and irritability, A fine tremor of your hands or fingers, Heat sensitivity and an increase in perspiration

Graves’ disease can cause multisystem syndrome known as thyrotoxicosis. This syndrome is the result of increased hormones produced by the excessive stimulation to the sympathetic nervous system. Diagnosis in elderly patients can be difficult to detect due to the symptoms being unclear and often mimicking aging. Also, other disorders can attribute to trouble of finding and pinpointing the disease (Weeks 35). Exophthalmos is a more severe yet common symptom observed within 20% to 40% of all patients with Graves’ disease. This is when excessive amounts of fluid accumulate behind the eyes. This causes inflammation within the tissues behind the eyes and edema occurs. The eyeballs tend to protrude out of the orbital sockets. This causes irritation, tearing and corneal abrasions. Also due to the protrusion of the eyes, the sclera above the iris becomes exposed not allowing the eyelids to cover the eye entirely (Weeks 35).

Grave’s disease is a disorder of the immune system causing the body to have an overproduction of hormones to the thyroid gland (hyperthyroidism). I chose this disease because I’ve known of a few people that have had difficulties with their thyroid’s. I wanted to learn more about it to be able to make other’s aware that they should have their thyroid checked regularly. The signs and symptoms that are associated with Grave’s Disease are anxiety, weight loss, puffy eyes, hand tremor’s, heat sensitivity, and the most noticeable is the enlargement of the thyroid. They can also experience insomnia, irritability and hair loss. Even though individual’s may have these signs and symptoms, this disease does require a medical diagnosis from a doctor.

The thyroid is a part of the endocrine system. The thyroid produces two hormones that affect metabolism, heart function and brain development. The hormones also helps regulate body temperature, weight and skin dryness. The two hormones that the thyroid secrets is triiodothyronine (T3) and thyroxine (T4). Thyroid-Stimulation hormone (TSH) is secreated by the pituitary gland, also part of the endocrine system, regulates the production on thyroid hormoes. If thyroid hormones are low the pituitart gland releases more TSH and if the thyroid hormones are hign less TSH is released. If someone is has Hashimoto’s disease the function of the thyroid and pituitary gland is affected and starts to decrease the thyroid hormones in the body and causes the pituitary gland to release more TSH into the

Graves’ disease, also known as hyperthyroidism is an autoimmune disorder that occurs when antibodies overstimulate thyroid stimulating hormone (TSH). Hyperstimulation of TSH receptors leads to an increased amount of circulating triiodothyronine (T3) and thyroxine (T4). An increased production of T3 and T4 lead to an increased metabolic rate. This can lead to clinical manifestations of diaphoresis, heat intolerance, increased cardiac output, tachycardia, exophthalmos and weight loss. If untreated, hyperthyroidism can turn into a thyrotoxic crisis, triggered by stressful events. Thyrotoxic crisis exceeds the metabolic strains on the body. Clinical manifestations such as hyperthermia, tachycardia, and heart failure can lead to death within forty-eight

The main cause of hyperthyroidism Graves’ disease which affects quite a few people in the general population. This disease is characterized as an autoimmune disorder. This means that the body makes antibodies known as thyroid stimulating immunoglobulin that bind and over activate the production of thyroid hormones [3]. So in essence the antibody mimics the thyroid stimulating hormone and when the negative feedback loop is in affect the antibody still binds to the thyroid and T3 and T4 are over produced [2].

Doctor Robert J. Graves, in which this disease was named after, first noticed Graves’ disease in a patient during 1835. However, no one knows what exactly caused this disease; it causes the thyroid gland to produce too much thyroid hormone (hyperthyroidism). In which your immune system then creates an antibody that causes the thyroid to grow and make more thyroid hormone than your body needs. Graves’ disease is a genetic condition that affects women more than men.

First, Hyperthyroidism if left untreated it would be difficult for the body to oxygenate or utilize nutrients as well as not being able to move waste out from cells. Hyperthyroidism induces

Hypothyroidism means that the thyroid does not produce enough of their hormones, and this usually occurs as a result of thyroid dysfunction in themselves. If a person solve its removal, the body is powerless to create the appropriate hormones, and if you remove just one part of it, being able to take them a while longer produced in sufficient quantity, but eventually burns in spending.

On Thursday, May 3, 2018, my general practitioner, Dr. Marcus Martinez during a routine physical, made me aware, that I more than likely have Graves Disease. This is a disease of the thyroid gland. I have multiple nodules/goiters that have grown over time, which will more than likely require surgery, and radioactive iodine treatments to mention a few options before me. At this time, it has yet to be determined if they are cancerous or malignant, that is the next step. It will be some time before a substitute daily drug for the balance of my life will function and produce the necessary hormones to function properly as a replacement for my thyroid gland hormones. These hormones or replacement drugs are a life’s necessity, and stimulate so much of the natural body functions. With this before me, I have been referred to an Endocrinologist, Dr. Gorson. Should confirmation be

Did you know that every cell of the human body has thyroid hormone receptors? They're intricately woven into the DNA. So, if you think about it, the thyroid gland basically has control of the entire body. As part of the endocrine system, the thyroid secretes hormones directly into the bloodstream, and these hormones are responsible for regulating many bodily functions. It controls the body's metabolism, protein synthesizing, energy consumption, and the functions of other vital organs.