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Appendicitis is one of the most common surgical diagnosis in the emergency department. Recent

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Appendicitis is one of the most common surgical diagnosis in the emergency department. Recent literature has supported the safety of nonoperative management of uncomplicated appendicitis. The APPAC trial was recently started in Finland to provide level 1 evidence to the hypothesis that at least 75% of patients with uncomplicated appendicitis can be managed effectively with antibiotics. Another study by Abes M et al has demonstrated 93.7% success rate in the non operative management of pediatric patients with uncomplicated appendicitis by limiting non operative management to patients with hemodynamic stability, a short history of less than 24 hours, without the signs of peritoneal irritation, necrosis or appendicolith. There is low …show more content…

Treatment failure was defined as subsequent readmission for any form of appendicitis, drainage of appendiceal abscess or appendectomy within 30 days of index admission. Recurrence was defined as a subsequent admission for any form of appendicitis, drainage of abscess or appendectomy at any time after 30 days from discharge. Among these two categories, patients were classified as perforated and non perforated. Treatment cost, length of stay and in hospital/30 day mortality rates were assessed as secondary outcomes.
Objective of this study was to assess the rates of treatment failure, recurrence, post discharge perforation, mortality, total cost and length of stay in the non operative management of uncomplicated appendicitis. Retrospective analysis was conducted using the data from the California office of state wide health planning and development. Patient discharge data was included from 1995 to 2010. Only patients with ICD-9 diagnosis code of 540.9 were included. Admissions in the year 2009 and 2010 were not included to allow at least two years of follow up. Charleson index was calculated to assess patient’s comorbidities. A total of 2,31,678 patients with acute uncomplicated appendicitis were identified. 98.5% were managed with appendectomy. Only 3370 patients were managed nonoperatively and were included in the study for analysis. There was significant difference in the characteristics between non operative and surgical cohorts. Non operative patients were older and

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