Breast cancer is a type of cancer originates from breast tissue, generally from the inner lining of milk ducts or the lobules that supply the ducts with milk. Cancers originating from lobules are known as lobular carcinomas whereas from ducts are called ductal carcinomas. (Ref: Breast Cancer, National Cancer Institute) Invasive breast cancer is breast cancer that has spread from the point of origin in the breast ducts/lobules to the surrounding normal tissue cells. In exceptional cases, breast cancer can start in at other sites in breast. Breast cancer occurs in both women and men, though male breast cancer is uncommon.
Many breast cancers are sensitive to the hormone estrogen. Thus estrogen leads to development of breast cancer tumor
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In the past, female patients with HER2-positive breast cancer had a more violent disease. They had a higher risk that the disease will recur as compared to the women who didn’t have this type. This may be changing with distinctively targeted treatments against HER2.
Breast Cancer Stages: Once the patient has been determined to have a malignant tumor or is gone through the diagnosis of breast cancer, the healthcare professionals will categorize it in staging method to communicate how far the ailment has progressed.
1) STAGE 0 :
At stage 0 no obvious symptoms of breast cancer are observed. It is the early stage i.e non-invasive breast cancer, this is termed as Ductal Carcinoma in Situ. (DCIS). The tumor cells though have originated but at this early stage no sign of active cancerous cells originating or spreading around the site of origin in the breast are observed. The cancer detected at this stage doesn’t require chemotherapy or radiation treatment instead lumpectomy is helpful.
2) STAGE 1:
At Stage 1 the break through of cancerous cells start and they invade the surrounding normal functioning cells in the breast, where they originated. This is the invasive breast cancer. Stage 1 is further divided into 1A and 1B substages.
Stage 1A: is the invasive form of breast cancer in which a 2 centimeter tumor lump is formed. The cancerous cells yet not spread around and the invasion of normal cells by tumor is nil. This
Invasive ductal carcinoma is the most common type of breast cancer. Invasive ductal carcinoma starts in one of the milk ducts in the breast, spreads through the wall of the duct and into the fatty tissue of the breast. Once it has spread outside the duct it is possible to spread to other parts of the body through the lymphatic system and blood stream. Some signs and symptoms of invasive ductal carcinoma can include: a lump in the breast tissue or armpit area, redness, thickening, irritation or dimpling, breast pain and or swelling, and nipple changes and or discharge. (American Cancer Society, 2014., National Cancer
This paper aims to provide the gaps in our understanding of breast cancer by examining the functions and to enhance our ability to distinguish the anatomy of female human breast. The author also attempts a better understanding of some of the different types of human breast cancer namely: ductal carcinoma in situ, lobular carcinoma in situ, invasive ductal carcinoma and invasive lobular carcinoma. It is hoped that this paper will inform those who do not have the understanding and knowledge about the risk factors, diagnosis, treatments and preventions of the breast cancer.
Another factor that contributes to the development of breast cancer is actually the hormone estrogen. This seems unusual because estrogen is a hormone that is essential to the bodies of women in various ways. Estrogen is necessary for normal growth and development of breasts and reproductive organs, as well as for the maintenance of a healthy heart and bones. However, lifetime estrogen exposure may increase a woman’s risk of developing breast cancer. It does not actually produce the mutation in the DNA, nevertheless Estrogen stimulates the proliferation of breast cells that already contain a mutation. These mutated cells will continue to reproduce and have an increased chance of becoming cancerous.
Breast cancer is not just a single disease. It may come in different types. One particular type and the most common is the invasive ductal carcinoma or the infiltrating ductal carcinoma. This is cancer that invades the surrounding breast tissues as it breaks through walls of the milk duct. Ductal carcinoma in situ (DCIS) is another type of cancer. This is non-invasive, meaning it does not spread to the surrounding breast tissues. Another type is the triple negative breast cancer. This happens when estrogen, progesterone, and HER-2, which fuel cancer growth, are not present in the tumor. This also means that hormone therapy and drugs are ineffective for this type, but chemotherapy may an effective option. Inflammatory breast cancer is a fast-growing type that caused to penetrate the skin and lymph vessels. For metastatic breast cancer, cancer basically spreads to other body parts including the lungs, bones, brain, or liver. This is also classified as Stage 4 breast cancer. The above mention cancer types are the commonly seen cancer cases. However, there are other types which are not commonly seen such as the medullary carcinoma accounting for 3-5% of cancer types, tubular carcinoma making up about 2% of diagnosis, and mucinous carcinoma representing 1% or 2% of all cancer types (National Breast Cancer Foundation Inc., 2016).
Breast cancer begins with out of control growth of the cells in the Breast tissue. A malignant tumor is a group of cancer cells that grow into tissues or spread to other areas of the body.
Breast cancer is a malignant tumor in the glandular tissues of the breast. Such tumors, also called carcinomas, form when the chemical processes that control normal cell growth break down, enabling a single abnormal cell to multiply at a rapid rate (Hickman). Carcinomas,
Cancer is defined by the National Cancer Institute as “the name given to a collection of related diseases. In all types of cancer, some of the body’s cells begin to divide without stopping and spread into surrounding tissues.” Cancer can develop at almost any part of the human body and anyone can develop cancer, although risk typically increases with age because most cancers tend to require many years to develop. “Normally, human cells grow and divide to form new cells as the body needs them. When cells grow old or become damaged, they die, and new cells take their place. When cancer develops, however, this orderly process breaks down. As cells become more and more abnormal, old or damaged cells survive when they should die, and new cells form when they are not needed. These extra cells can divide without stopping and may form growths called tumors” (cancer.gov). Cancerous tumors are defined as malignant meaning that they can spread to nearby tissues or metastasize to distant places in places within the body and form new cancerous tumors. There are over 100 forms of cancer and they are usually named after the organs or tissues where the cancers originate. Staging of cancer is used to “describe the severity of a person’s cancer based on the size and/or extent (reach) of the original (primary) tumor and whether or not cancer has spread in the body” (cancer.gov). The importance’s of staging cancer is to assist the doctor with planning appropriate treatments to fight the cancer
This paper will inform you of Breast Cancer. It is the most common form of cancer in women today but thanks to medical advances it is no longer the number one killer of women.
Breast cancer is a kind of cancer that begins in breast cells. Breast cancer can be labeled as invasive or non-invasive.
Metastatic breast cancer can spread in a variety of different ways, the first being invasion of healthy cells by cancer cells. Once the healthy cell has been taken over it can begin to reproduce more abnormal cells, which is why cancer cells grow so uncontrollably. Some other ways the cancer spreads incudes’, lodging into capillaries, penetrating the lymph system, migration through circulation, or just
To hear you have breast cancer can be a very shocking thing. “Besides skin cancer, breast cancer is the most common cancer diagnosed among women in America as of 2015” (breastcancer,2015). First step is to know what you are dealing with when your doctor believes you have cancer, you will want to know what cancer is and how your doctor can detect it. Next your doctor will go over different stages of breast cancer that will help come to a conclusion on your next step. Lastly you and your doctor will go over the different treatment plan that best fits you. This journey a women or man will take when being diagnosed with cancer is a long and hard one but, with the help from your doctors and the knowledge you can get through this.
Breast cancer is when a cell divides uncontrollably and doesn’t receive the signal to stop dividing (Types of Breast Cancer 2015). When the cancer is malignant it tends to spread throughout the body usually spread by the lymph system. The lymph system can spread the cancer through the bloodstream to other organs or parts of the body
In addition, there are more than 18 other sub-types of breast cancer. Some cancers develop from pre-invasive lesions such as ductal carcinoma in situ. The diagnosis of breast cancer is confirmed by taking a biopsy of the concerning lump. Once the diagnosis is made, further tests are done to determine if the cancer has spread beyond the breast and which treatments it may respond to.
This is the stage that is the easiest to cure. Stage 1 cancer is cancer that hasn’t grown too far into the tissues surrounding it and is also called early-stage cancer. Stages 2 and 3 cancers are cancers that are larger or have grown further into the neighboring tissues and have moved to the lymph nodes, but not to other body areas. Stage 4 cancer is cancer that has moved to organs and other body parts. This cancer is also called advanced or metastatic cancer.
There are four stages of breast cancer. The Stage 0 is noninvasive breast cancer, that is, carcinoma in situ with no affected lymph nodes or metastasis. Stage zero is the most favorable. Now Stage 1 breast cancer is less than two centimeters in greatest dimension and is only in the breasts. In Stage 2, the cancer is no larger than two centimeters but it has spread to the lymph nodes under the arm. The