Cannabinoid Therapeutic Analysis

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CBD has positive effects on reducing and managing psychotic, anxiety, and depressive-like behaviors. The mechanisms appear to be related to the CBD's benefit to provide enhanced neuroprotection and inhibition of excessive neuroinflammatory responses in neurodegenerative diseases and conditions. Common features involving neuroprotective mechanisms influenced by CBD—oxidative stress, immune mediators, and neurotrophic factors—are also important in conditions such as posttraumatic stress disorder (PTSD), postconcussion syndrome, depression, and anxiety. Many studies confirm that the function of the ECS is markedly increased in response to pathogenic events like trauma. This fact, supports the role of cannabinoids and their interactions with CB1 …show more content…

High incidences of continued or worsening psychiatric or mood disorders, adventitious side-effects leading to poly-pharma. Often there is a high stigma with admitting to having a psychiatric condition that inhibits or delays care and leaves a vulnerable population untreated. Cannabinoid therapies offer and autonomous and readily available approach to doctors, patients and their families. Patients would potentially be able to self-medicate without the “stigma” of seeking professional help. Which may allow service and treatment to a greater population. (Maa & Figi, …show more content…

Patients with alcoholism often go through cycles of binging on alcohol, stopping for short periods of time due to experiencing feelings of remorse for behavior done under the influence and inevitably returning to drinking in excess. (Mikuriya, 2004). Additionally, long term use of excessive amounts of alcohol can lead to debilitating diseases and eventually death. Cannabis though, has been shown in some cases to be an effective substitute for alcohol aiding patients in their struggle to reduce or stop alcohol use. (Mikuriya, 2004) With its relatively benign side-effects, this makes cannabis a more favorable alternative. In Mikuriya’s (2004) study, 92 patients who had alcohol addictions used cannabis primarily to treat alcoholism, with patients listing depression, pain, and insomnia among secondary reasons for use. Patients were interviewed, and medical records reviewed for information regarding the extent of alcoholism and any current or former treatments (Mikuriya, 2004). During follow-up visits, typically every 12 months, patients reported what conditions they were using cannabis to treat, as well as how effective they found the treatment to be (Mikuriya, 2004). Of the patients that reported back, 45 ranked using cannabis as a “very effective” treatment, and 38 ranked it an “effective” treatment option. (Mikuriya, 2004). While total abstinence was an unattainable goal for some patients,

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