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Cause And Effect Of Hydrocodone

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Hydrocodone a drug used to change how your brain and your nervous system reacts to pain. When taken the medication correctly it should relieve mood, reduction of pain. Hydrocodone was introduced in the 1920’s from the country of Germany. Carl Mannich and Helenen Lowenheim were the first to report it being in use in 1923( Eckenrode, S. L. (2015).Hydrocodone is a form of opiate, analgesic, it is described as white crystals as a crystalline powder and reacts to light. This drug classified as a schedule II drug known as a controlled substance. Hydrocodone is often always found in combination with acetaminophen such as Vicodin and Lortab (Advokat, C. D., Comaty, J. E., & Julien, R. M. 2014). As of 2012, the United States Hydrocodone is the most used drug prescribed to treat pain. The United States has consumed 99% of this global supply for 4.4% of the worldwide population. (Manchikanti, L., Atluri, S., Kaye, A.M., Kaye, A.D). The US Drug and food administration approved the drug for sale in the United States in 1943.
Mechanism of Action The Mechanism of Action in Hydrocodone is not known, but it is believed it Opioid receptors againist the central nervous system. What we do know is that it the source of the hydrocodone is Semisynthetic with two naturally occurring opiates, codeine, and thebaine (Eckenrode, S. L. (2015). Neurotransmitters effected from the usage of hydrocodone is the brain neurotransmitters. It can impair brain function to where you can’t function normally without having the drug in your system. The neurotransmitter control movement, mood, digestion, body temperature, and breathing. Using this medicine can cause the neurotransmitters to discharge ant and faster rate. Your brain produces its chemical to control pain and other body functions. Your mind can stop producing its compound and start to rely on the opiates that are inside of the Hydrocodone.
Dosage, Administration, Absorption, and Metabolism
Hydrocodone is available in a variety of dosages with acetaminophen. When taken oral the dosage can range from 5mg-to 10 mg tablets. Time administration interval of every four to six hours as needed Eckenrode, S. L. (2015). The recommended dose for chronic acetaminophen is 3000 mg/day. Hydrocodone

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