Perchlorates are inorganic chemical compounds that have a pounding effect on human health and especially on the thyroid homeostasis. The growing levels of perchlorates in drinking water and industrial waste have a detrimental impact on the public health in various ways. This report tries to correlate the impact of perchlorates and their effect on the human population. The damage caused by perchlorates varies from person to person and is governed by a set of factors like the duration of the exposure, amount of exposure, age group, gender and lifestyle. Perchlorates acts by competitively inhibiting the sodium/iodide symporter and thereby blocks the iodide intake into the thyrocytes leading to a decrease in T3 and T4 hormone secretions. However different EDC’s (Endocrine Disruptor Chemicals) have their own corresponding mechanisms of thyroid homeostasis disruption. To look into the possible benefits of perchlorates, KClO4 has a role in the treatment of hyperthyroidism since it was a potential inhibitor of sodium/iodide symporter blocking the thyroid hormone synthesis. Although it may or may not maintain constant thyroid homeostasis (Euthyroidism) upon treating with the potassium perchlorate. The hazardous incidence of perchlorates can be discussed in a broad way and are dependent on the various above mentioned factors. In fact, even a lenient hypothyroidism have a profound impact in pregnant women and infants, causing neurological defects and
Also depicted in this paper is the type of cancers caused by each chemical and other related health problems associated with each chemical. Finally, the role of government agencies such as FDA, EPA and OSHA in preventing excessive amount or zero amounts of toxic chemicals from entering the environment will be discussed. The last paragraphs will enumerate the inferred conclusion from my research on Agent Orange, DDT and Benzene.
Also depicted in this paper is the type of cancers caused by each chemical and other related health problems associated with each chemical. Finally, the role of government agencies such as FDA, EPA and OSHA in preventing excessive amount or zero amounts of toxic chemicals from entering the environment will be discussed. The last paragraphs will enumerate the inferred conclusion from my research on Agent Orange, DDT and Benzene.
Water is an essential quality in life that you need to live. Yet many people don't realize that how important it is in life until it could be taken away. John Thorson, a water rights and lawyer, says “ water links us to our neighbor in a way more profound and complex than any other.” It is a way people are connected around economically, socially, and environmentally. Some struggle to have clean water to drink and others can not find clean water at all.
TCDD is a dioxin that can be produced through diesel exhaust, burning waste, and chemical manufacturing. In recent years, many have argued that exposure to this chemical can cause serious illnesses. Studies on animals have shown that TCDD is one of the most poisonous chemicals out there. The animal testing has been found to be especially toxic to developing babies in the womb. A pregnant rat given a dose of less than one part per billion (which is comparable to a single drop in 14,000 gallons of water) will cause female sexual characteristics in a male embryo. Doses of 100 parts per billion in rodents and fish have been proven to cause birth defects such as cleft palates, malfunctioning kidneys, heart problems, and weak bones (Schmidt). Animal studies have proven that small doses of TCDD can be severely detrimental to one’s
Carson talks about how toxin and chemicals could kill all the insects and animals that bring songs of life to this planet.
Following the industrial revolution, societies across the world began to notice strange effects on individuals throughout certain local communities. Though toxicology was a relatively new and rudimentary practice at the time, scientists were able to trace these effects back to chemicals being exposed to industrial workers, their families, and nearby neighborhoods. Unfortunately, industry in the United States continued to expand with little regard for the effects on human health. As a result from this expansion the amount of chemicals released into the atmosphere skyrocketed continuously all the way to present day society. However, as industry expanded so did scientific technology, the understanding of chemicals, their exposure
Some of the pollutants released include: toluene, benzene, xylene and ethyl benzene, ground level ozone (also known as smog), nitrogen oxides, carbon monoxide, and formaldehyde. Exposure to these pollutants are known to cause short-term illness, organ damage, nervous system disorders, cancer, birth defects and even death in some cases. Some of the cancer causing are this; Dioxin is formed when chlorine breaks down, and can be found in both water and air. Dioxins are known human carcinogens and endocrine disruptors. One dioxin has been classified by the International Agency for Research on Cancer (IARC) and the Environmental Protection Agency (EPA) as a known human carcinogen. Organic solvents are a class of chemicals that includes chlorinated and other solvents, including toluene, methylene chloride, trichloroethylene and formaldehyde. Sources of exposure include outdoor and indoor air pollution, waste incineration, cleaning products and some cosmetics. They are also used in the manufacture of computer parts. Many pesticides that are included in the fluid, including herbicides and other pest-killing poisons, have been labeled as human or animal carcinogens. A report demonstrated that lifetime use of residential pesticides may be associated with an increase
The health hazards for humans who come in contact with contaminants from exposure to polluted water can have long term effects on the body causing possible organ failure and death. Contaminants and chemicals such lead and mercury can bring about many minor illnesses ranging from nausea, lung irritation, skin rash, vomiting, and dizziness, to the major diseases that include cancer, liver and kidney damage, disorders of the nervous system, damage to the immune system, birth defects and even death.
The last endocrine disrupting chemical I will discuss is Triclosan. The chemical found in Triclosan is Triclocarban. The products that contain this endocrine disruptor are personal care products and antimicrobial products such as soaps and Colgate Total toothpaste. In (Greenfield’s 2016) view, "The effects Triclosan has on animal and human tissue is early puberty, poor sperm quality, infertility, obesity, cancer, impaired learning and memory exacerbate allergies and weakened muscle function." Even though most people try to prevent the health issues associated with Triclosan, the chemical is still exposable because of the people that still use it. For example, once the toothpaste is used it goes down the drain which is connected to the waterways, food, and environment. In addition, Triclosan is in the toothpaste Colgate Total which makes it a dangerous product but it is very successful and would take a lot to get it took off the market completely to prevent health issues.
Five environmental agents that can cause disease in humans are mercury, lead, radiation, air pollution, and pesticides. People are exposed to mercury in different ways. For example, a common way is by eating fish containing mercury or being exposed to broken products that contain mercury (thermometer). People are exposed to lead by exposure to lead-based paint and pipes of older buildings, as well as, ingesting contaminated water. We are exposed to radiation through the sun's UV radiation or x-rays people get when getting checkups in the hospital. As for air pollution, people can be exposed to CO2 emissions from cars, factories, and cities in general. Another way is being exposed while indoors by CO that comes from appliances that have no odor,
Researchers at UCLA were able to determine what kind of threat the chemicals posed on the “reproductive neuroendocrine system” of fish when they were exposed to low levels of both BPA and BPS. Senior author on the study and reproductive endocrinologist, Nancy Wayne, spoke to CNN about her findings: “Our research showed that low levels of BPS had a similar impact on the embryo as BPA.” Wayne spoke to the effects this could potentially have on humans as well, saying: “Because of thyroid hormone's important influence on brain development during gestation, our work holds important implications for general embryonic and fetal development, including in
Most individuals are not aware of the things that are bad for the body until a noticeable reaction occurs. With this in mind, endocrine disrupting chemicals are chemicals that interfere with our endocrine system causing a problem. Therefore, in this paper, I plan to inform you about three endocrine disruptors that are bad for the human body known as flame retardants, phytoestrogens and triclosan. I will contain information about the chemicals found, products that they are located in and the effect they have on animal and human tissue. Next, I will show a relationship between endocrinology and endocrine disrupting chemicals on affecting homeostasis and discuss my reaction to the information I learned and how I feel about it overall.
During recent years, numerous newspaper and magazine articles have suggested that humans may be at risk because small amounts of well known environmental contaminants, such as dioxin, PCBs and DDT, can affect hormone levels. Hormones are produced by the endocrine system as regulators of biological function in target organs. Because hormones play a critical role in early development, toxicological effects on the endocrine system often have an impact on the reproductive system. The term endocrine disruptor is used to describe chemicals that can mimic hormones and may either enhance or counteract their effects. It has been suggested that these hormone changes can, in turn, lead to a variety of health problems
Many scientific researchers have said that our environment has been filled with toxic chemicals, which us humans have had a part of. There are many different issues that should concern us surrounding these toxic chemicals. The major concern is that many of these toxic chemicals have been claimed to be causing damage to the health of humans and even other life forms. Another concern is that most of the theses toxic chemicals have just recently been produced; and by our environment changing everyday there is no telling what effects these toxic chemicals may have in the long run on the public 's health. Just about all of these toxic chemicals exist in the way they do because of humans. As humans we practice a lot of different activities that cause toxic chemicals to pollute our environment such as, agriculture, industrial, and many domestic activities as well. Many of the toxic chemicals that we produce and use don 't get used in a effective way, which causes them to be wasted, left abandoned, and disposed of. When toxic chemicals are not disposed of properly they effect the environment and the public 's health in a negative way.
In a cross-sectional study on humans showed an Inverse associations between Organochlorine (OC) pesticide concentrations (endosulfsan) and testosterone in men, suggest that these OC compounds may have triggered anti-androgenic effects in men and estrogenic effects in women in this population20.