preview

Congestive Heart Failure: A Case Study

Good Essays

Introduction
I chose my PICO question, “In patients with Congestive Heart Failure, does BNP-guided therapy result in better outcomes than Symptom -guided Therapy?” because of my interest and fascination about the heart and also because of my extensive family history of cardio-vascular issues. According to the American Heart Association and the American College of Cardiology Foundation (2013), heart failure is a “complex clinical syndrome that result from any structural or functional impairments of ventricular filling or ejection of blood” (p. e246). Heart failure is the primary diagnosis for >1 million hospitalizations annually, with > 650,000 newly diagnosed cases per year, and it costs $30 billion annually in overall care for this condition …show more content…

With new research emerging, new tests and measures are being discovered to provide potential additions to improve the diagnostic and treatment process. One of these is the B-type natriuretic peptide (BNP). According to Porapakkham, Porapakkham, Zimmet, &, Billah, B., & Krum (2010), BNP is a neurohormone primarily released from the heart’s ventricles in response to the stretch that is received when the heart is filling. The greater the stretch received by the heart, more of the neurohormone is released into the bloodstream. This has been seen as an invaluable and also a minimally invasive indicator of volume status and a measurable value of the heart’s ability as a pump. My question arose from the curiosity of whether using BNP as a guide in treatment of heart failure patients will provide better clinical and subjective outcomes not just for the patients but also for treating practitioners. The following is the summary and synthesis of the articles, Meta-analysis and practice guideline that pertains to the PICO question …show more content…

The first article, Treatment of Heart Failure Guided by Plasma Aminoterminal Brain Natriuretic Peptide (N-BNP) Concentrations, has aimed to explore if the utilization of N-BNP in intense treatment of HF including drugs will result in better outcomes compared to treatment based on standard clinical assessments. The study was a randomized, controlled study; double blinded. The primary outcomes/endpoints were total cardiovascular events as defined by death or any hospital visit or admission related to CV events. Secondary outcomes were lower BNP levels, LV functions and quality of life. A statistical significance if p value is < 0.001. Hospital stay r/t heart failure was more numerous in the control group (p<

Get Access