Introduction
Cystic fibrosis (CF) is an inherited chronic disease that must be carried by both parents in order to for the person to suffer from it. If one of your parents has it, then you will definitely be a carrier of the disease and it will be carried to your offspring. Children who inherit a faulty CFTR gene from each parent will have CF.
This disease affects organs such as the liver, lungs, pancreas, and intestines.
This disease disrupts the body’s salt balance leaving too little salt and water on the outside of cells which makes the thin mucus that protects the linings of the airways, digestive system, reproductive system, and other organs and tissues free of germs become thick and sticky thus clogging the airways and damaging the lungs.
…show more content…
Over time, cystic fibrosis can damage lung tissue so badly that it no longer works. Lung function typically worsens gradually, and it eventually can become life-threatening.
Digestive system problems:
Nutritional deficiencies can occur.
Diabetes, nearly 20 percent of people with cystic fibrosis develop diabetes by age 30.
Blocked bile duct. There is a tube that carries bile from your liver and gallbladder to your small intestine. That tube may become blocked and inflamed which leads to liver problems and sometimes gallstones.
Intestinal obstruction. This can occur at any age especially children with CF are at a higher risk for intussusception which is a condition that causes a section of the intestines to fold in on itself like an accordion.
Distal intestinal obstruction syndrome (DIOS). DIOS is partial or complete obstruction where the small intestine meets the large intestine.
Reproductive complications:
Almost all men can become infertile because the tube that connects the testes and prostate gland (vas deferens) is either blocked with mucus or missing entirely. Some treatments might be useful for the possibility of them to become
…show more content…
When someone has Cystic fibrosis this gene is broken and doesn’t function normally.
Treatment:
Cystic fibrosis can not be cured, it is chronic, but treatments could be helpful to ease the symptoms. There are techniques to help you get rid of the thick mucus, for example, the airway clearance technique, there is a common method called postural drainage and percussion. Which where you will sit or lie in different positions to let the thick mucus flow from your small airways in your lungs to the large ones, then someone or you could tap your chest to ease the mucus more so you could cough and get rid of it.
“Inhaled drugs like dornase alfa (Pulmozyme), albuterol, salt solution, steroids, or antibiotics thin mucus, clear the lungs and fight infections. Medicines such as ibuprofen fight inflammation and reduce swelling in your lungs.” (webmd)
Taking enzyme pills will help in digesting fats and proteins and absorb more vitamins from your food. Also taking vitamins A, D, and E can help in replacing nutrients that your intestines can't absorb. There is also oxygen therapy which helps if you have severe lung disease and need to breathe oxygen through a mask or prongs in your
One of the distinguishing features of cystic fibrosis is the thick mucus that lines both the airways and the intestinal tract of affected individuals. In the respiratory tract, this thick mucus is not removed by the cilia that usually beat and push mucus up into the throat. This thick mucus builds up in the airways, and bacteria trapped in the mucus are not removed. Thus bacterial respiratory infections are extremely common.
This is due to the lack of the vas deferens, which is the tube that sends the sperms out of the testes to the penis. In woman they can have children they just have more problems with conceiving due to the excessive amounts of mucous in the sexual organs.
To begin, cystic fibrosis is a genetic disease that causes persistent lung infections and limits the ability to breathe over time. It is an inherited disorder both parents have to be a carrier of the gene. Some people say if a both parents have the gene then their is a 50% chance that the mother will have a baby with the disorder. It affect the
Today, there is no cure for Cystic Fibrosis, but if the disease is found in an individual early enough, the patient can be recovered. About 85 to 90% of patients will have problems absorbing nutrients from their intestines. And because enzymes are lost when diagnosed, enzyme supplements are required to prevent bad nutrition and malnutrition. There are two main body parts that can be cared for the treatment of Cystic Fibrosis: The lungs and the chest. Lung problems can also be treated, but not cured. Antibiotics and other drugs may loosen the thick mucus in the lungs, but if it fails, a transplant lung may help to extend life. But about four hundred people die each year while waiting for a lung transplant. Also Chest physical therapy is a technique done by vigorous claps on the back and chest to loosen the thick mucus from the lungs. The average lifespan of an individual with CF is about thirty years.
Five year old Ellis Miles undergoes numerous treatments each day to counteract the symptoms that accompany cystic fibrosis including physiotherapy, pills containing digestive enzymes, and a treatment which breaks up the mucus in her lungs. Cystic Fibrosis has numerous life threatening symptoms and while there is no cure, there are several treatments that a typical patient undergoes each day to combat these symptoms. The most prominent symptom associated with Cystic Fibrosis is a thick mucus that clogs up tubes that carry out crucial roles in the human body. This mucus especially affects the respiratory tract. Mucus builds up in the respiratory tract making it difficult for individuals with cystic fibrosis to have a frequent cough that produces a thick
Cystic fibrosis is an inherited disorder that affects many functions of the body: breathing, digestion, and reproduction. The lifelong illness usually gets more severe with age and can affect both males and female equally. The symptoms and severity of cystic fibrosis differ from person to person. Most patients have both respiratory and digestive problems, while others only have respiratory problems. Intelligence is not affected in people with CF.
Cystic fibrosis is a disease that is continually affecting children and adults in the United States. This is an inherited and life-threatening disease which affects many organs in the body. According to the Center for Disease Control, there are an estimated 30,000 people affected by this disease today. There are also approximately 2,500 babies born each year with Cystic fibrosis and unfortunately there are millions of people unaware they even carry the gene for this disease.
If a child is born with Cystic fibrosis it means that both parents must carry the CF gene. About 80% of parent who have a child with CF didn’t know that they were carriers. When each parent has the CF gene and have children it will result in a 1 in 4 chance that the child will have CF, a 2 in 4 chance that they will not have CF but will be a carrier or a 1 in 4 chance that they will not have CF or be a carrier.
But because the type/severity of cystic fibrosis can differ from one person to another by a lot, there isn’t any normal treatment plan. One common treatment therapy is airway clearance, in which the affected person wears a vest that vibrates at a high frequency, which loosens and thins the mucus buildup. Another is the usage of inhaled medicines. These medicines help open airways and thin the mucus buildup. The medicines are liquids that are made into a mist and inhaled through a nebulizer. The medicines have antibiotics to help fight lung infections. Also, there are pancreatic enzyme capsules, which help improve the absorption of vital nutrients, and are normally taken with most meals and snacks. In addition to the capsule, people with the disease usually take multivitamins. Two relatively new treatments are a type of drug called a CTFR modulator, which targets the defective CTFR gene. These drugs were only recently approved by the FDA, the first was in 2012, and the second just this year (2015). It is expected that the new drugs could add many years to the lives of people affected by Cystic fibrosis. Also, a cystic fibrosis specialist can treat you. The U.S has about 100 cystic fibrosis care centers, which have teams of doctors/nurses and respiratory/physical therapists who all specialize in Cystic fibrosis care/treatment.
One copy from each parent. Both parents must have at least one copy of the defective gene. People with only one copy of the defective CF gene are called carriers, but they don’t have the disease. This gene makes a protein not work very well which causes the thick mucus and very salty sweat.
Cystic Fibrosis can cause problems in the reproductive system. Cystic Fibrosis patients have many more sexual reproduction problems than a healthy human. In males with CF, they are likely to be infertile because of the tube connecting the testes and the vas deferens is missing or blocked with mucus. In women with CF, pregnancy can be a lot more difficult. Pregnancy can worsen the symptoms of Cystic Fibrosis. Women with CF may also be less fertile than women without CF. Women with CF should always consult with a doctor to know all of the possible risks. In order to get CF, both partners must be a carrier because the CF gene is recessive. If someone is a carrier, they could pass it on to their own child. Cystic Fibrosis tends to run in families, since it is an inherited disease. It is also most common in Caucasians.
Cystic fibrosis is a genetic disease that affects the respiratory system, digestive/endocrine, and reproductive system. A defective gene produces an abnormally thick mucus in the trachea and causes a blockage in the trachea, damages lung, and resulting in failure of the respiratory system. The mucus also interferes with the pancreas, which it prevents the secretion of digestive enzymes that help dissolve food, causing difficulty in absorbing nutrients. CF causes infertility, particularly in men. However, they are not sterile, therefore they can have children with assisted reproductive techniques. In most cases, many of them are diagnosed with CF before the age of 2 because the newborns are screened immediately after birth. On the other hand,
What is Cystic Fibrosis? Dr. Polit describes Cystic Fibrosis, also referred to as CF, the most common fatal recessive genetic disease among white people. It is a hereditary disorder, also known as mucoviscidosis, which disturbs the lungs, as well as the digestive system, by blockage due to the creation of abnormally thick mucus. According to the U.S. National Library of Medicine, “This abnormal mucus can clog the airways, leading to severe problems with breathing and bacterial infections in the lungs. These infections cause chronic coughing, wheezing, and inflammation”. Due to the buildup and infections, scar tissue forms as well as lung cysts causing permanent lung damage. It is also very common for those with cystic fibrosis to suffer from digestive problems because of the blockages caused by thick, sticky mucus in the body.
Cystic Fibrosis (CF) is the most common fatal genetic disease in the United States today. CF is an autosomal recessive disease that occurs approximately one out of 3,300 live births (Cystic Fibrosis Foundation, 1998). Autosomal means that the gene for CF is not carried on the sex chromosomes and males and females are both afflicted
This is a great improvement over survival rate of the 1950s with the life expectancy of 1 year or less for cystic fibrosis patients. Unfortunately, since it is a recessive genetic disease, there are many men and women who are carriers of the disease without actually having the disease themselves. If each parent is a non-affected carrier of cystic fibrosis, there is only a 25 percent chance of having a non-affected, non-carrier child and 50 percent chance of having a child that is a non-affected carrier of cystic fibrosis. Unfortunately there is also a 25 percent chance of having a child affected by cystic fibrosis. This makes prenatal genetic screening very important.