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End Stage Renal Disease Case Study

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The number of patients with end-stage renal disease (ESRD) requiring hemodialysis is constantly rising worldwide.1 Vascular hemodialysis access is considered the lifeline for patients with end-stage renal disease, and arteriovenous fistula (AVF) has been the golden standard access for hemodialysis.2 In Europe, over 25% of all hospital admissions for ESRD are for the construction or maintenance of a patent vascular hemodialysis access.3 While the life expectancy of ESRD patients continues to lengthen and with the limited durability of vascular accesses, repeat fistula construction at different levels of the upper limb is often necessary and leads ultimately to exhaustion of autogenous vascular access sites.4 Use of a synthetic prosthesis is …show more content…

A vein is considered unsuitable if an occlusion or high-grade long stenosis ( (-- removed HTML --) 4 cm long) of the vein or the venous outflow obstruction is detected and cannot be treated promisingly by any interventions. Patients with cardiac insufficiency that is intolerable to the additional cardiac load of a high-flow AV fistula were also enrolled. Exclusion criteria were patients with chronic ischemia of the limb, infection or huge ugly scar at loop site. All procedures were performed under general anesthesia. Two grams of 3rd generation antibiotic was administered with induction of anesthesia. The operative procedures included exposure of the first part of axillary artery, after separation of the artery, a PTFE graft with a 6- or 8-mm diameter (adapted to the diameter of the artery) was interposition after configuration of a subcutaneously tunneled loop on the chest wall (Figure 1). Figure 1: Demonstrating draw for axillary loop interposition graft. A 6/0 polypropylene suture was used in the creation of an end-artery to end-graft anastomoses between the ends of prosthesis and the first part of axillary artery (Figure 2). The length of the implanted graft was between 30 and 40 cm. The mean operation time was 102 minutes. Low molecular weight heparin therapeutic dose was administered once a day for five days then was replaced by oral anticoagulation warfarin for

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