Evaluation Of A Pilot Randomized Controlled Trial

Better Essays
Introduction In article, Immediate and Delayed Cord Clamping in Infants Born Between 24 and 32 Weeks: A Pilot Randomized Controlled Trial, Mercer reported possible issues regarding methodological assessment of the preceding research involving the capability to perform a meta-analysis of the seven studies. However, a pilot randomized controlled trial (RCT) aggregates on the present day literature on cord clamping by considering the feasibility, recruitment strategies, and key outcomes of the possible increases in blood volume as a result of delayed cord clamping (DCC) (Mercer et al., 2003). In the pilot RCT, Mercer and the team wanted to assess credibility of DCC and the study protocol in the authors’ institution. In addition, they wanted to test and generate hypotheses in order to set up the groundwork for funding for a larger RCT. The first hypothesis stated that DCC in very low-birth-weight (VLBW) infants would have an outcome of higher mean blood pressure after reaching the neonatal intensive care unit (NICU). The second hypothesis stated that VLBW infants would have higher hematocrits, fewer clinical acuity indicated by fewer days of ventilation and fewer days of oxygen use when compared to ICC (Mercer et al., 2003). The focus of the study was to establish feasibility of a protocol for DCC against ICC at preterm birth and, also to inspect its outcomes on initial blood pressure and other events. This kind of study was the first one to observe the outcomes of DCC in
Get Access