Introduction
Smallpox is a viral disease that causes pus-filled boils on the dermis. It looks similar to chickenpox, but has certain characteristic differences. Unlike chickenpox, smallpox is lethal in 30% of the cases and leaves the victim with disfiguring scars and/or blindness. Smallpox has now been eradicated through aggressive vaccination. The last case was reported in Somalia in the late 1970’s. After 2 years of worldwide surveillance, the World Health Organization (WHO) confirmed that the disease had been eradicated.
Causative agent
Smallpox is caused by the Variola virus, which belongs to the Orthopoxvirus genus. The members of this genus share similar genetic makeup and characteristics. Viruses belonging to this family are
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Disease transmission
Smallpox is transmitted via face-to-face contact and /or exchange of infected bodily fluids with the affected individual. The disease is transmitted to a lesser extent via infected clothing and bedding. Humans are the only natural host for the virus. Therefore, there is no reservoir and the virus is not transmittable through animals or insects. The incubation period of the virus is nearly 2 weeks (7 to 17 days) during which the person is asymptomatic and non-contagious (Fenner et al., 129).
Symptoms and diagnosis
After the incubation period, the person experiences symptoms such as fever (101 to 104°F), body ache, headache, malaise, vomiting and stomachache. At this point, the person becomes too sick to walk around and do their daily chores. This phase is called as prodrome that may last 2 to 4 days. The patient starts to feel normal after this prodrome phase only to experience the appearance of rashes in the form of red spots on the mucous lining of the mouth and on the tongue, 24 hours later. These spots rupture and release the virus into the throat. It is during this time that the rash starts appearing on the dermis of the face, arms and legs. Usually, the midsection of the body has less concentration of these spots when compared to the face and the extremities. This is the first
Smallpox is an extremely deadly disease which, in one point in time, was the most feared disease on the planet. In the book Pox Americana, Elizabeth A. Fenn writes about the encounter with the deadly disease in the 1770's to the 1780's. Her book was first published in 2001 in New York City, where she originally wrote it. Her book contains just under 400 words that explain the disease, some of the first encounters with it, who and where it affected people, and how they got the epidemic under control. Pox Americana is a very informative book that teaches the reader various things.
Smallpox is a disease caused by a poxvirus that is caught from person to person that causes high fever, and rash, that can kill about 1/3 of those who caught the disease. Smallpox (also called variola) is the only disease that has been fully cured. Smallpox is also almost one of the most scary deaths ever. Not one documented naturally occurring case of this very infectious, deadly disease hasn't occurred since 1977. (An unvaccinated hospital cook in Somalia was the last person to naturally contract smallpox.) The World Health Organization (WHO) officially declared smallpox eradicated in
What is smallpox? The internet has defined it as an “acute contagious immune disease, with fever and pustules (small bumps on the skin filled with pus) that will usually will leave scars.” Smallpox originated in India and Egypt over 3,000 years ago. After that it slowly started to progress to other areas across the world. It then started to show itself in places like Africa, Europe and then after a few years later, finally made it’s way into the Americas during the 1500’s.
In a letter to Patrick Henry in 1777, George Washington wrote of Small Pox “I know that it is more destructive to an army in the natural way than the sword”. At times the most minute things have the most immense impact on our lives, such was the smallpox Epidemic of 1775. It is not known how or where the outbreak began, but by 1775 it was raging through Boston. The devastation of Smallpox during 1775 played a key role in the outcome of the revolutionary war and in shaping modern medicine and how we handle diseases. But these medical advances didn't come without terrible sacrifice. Nearly 30% of people living in the Americas or 130,658 would succumb to smallpox. The death rate of Variola Major, which is the common form
Many parts of this epidemic are common to other epidemics of its kind. This smallpox epidemic affected the Native American tribes to the west, the North American colonies of France and England to the east and north, and the Spanish colonies to the south. Smallpox is contagious disease
There are many mysteries about the smallpox virus. Since the seventeenth century, doctors have understood that if the pustules merge into sheets across the body the victim will usually die: the virus has split the whole skin. If the victim survives, the pustules turn into scabs and fall off, leaving scars. This is known as ordinary smallpox.
Because the smallpox virus attacks the mucus membranes, bone marrow, and lymph nodes of the body, most patients obtain the gruesome disfigurement of the face and nose and limbs.( Bollet
Smallpox, also know as variola virus, is extremely contagious and lethal. In modern day it has been eradicated and we no longer vaccinate the human population. Symptoms begin 12-14 days after infection; after 1-2 days spots turn into blisters and then pustules and after 8-9 days these pustules become crusted. If the person survives, large disfiguring scars remain (Merck, 2003).
Smallpox is a viral infection caused by Variola major. This infection is currently one of the most dreaded diseases, and is believed to be more dangerous than the enemy’s sword. The exposure is usually an infection of the respiratory tract. After exposure, early symptoms are: headaches, back aches, fever, vomiting, discomfort, and feeling out of sorts. These symptoms go away usually in two days, and the patient feels better. Then about two days later, the patient has a flustered face, and lesions on the mouth, throat, and nasal membranes. At 5 days past exposure, red rashes and bumps appear on the skin, bleeding through skin, and mucous membranes. If the patients bleeds through their eyes, gums, or nose, the patient will not live much longer, but that is not usually the case. The bumps may touch each other or they may be separate from each other. If the bumps do not touch, the patients has a good chance of surviving. But if the bumps do touch, the patient has a forty percent chance of surviving. Dehydration is common in patients because it may be painful or difficult to drink. Around day ten, the bumps will become soft, and blisters will form. The fluid in the bumps is absorbed because of dehydration. A smell often comes from cracked bumps, and a second bacterial infection may occur due to the openings in the body. Two weeks after initial symptoms, the bumps and blisters are replaced by scabs. One week later the fever disappears, the patient returns to a normal life, and the
The first case of smallpox was found on the ancient Egyptian Pharaoh Ramses V in the 3rd Century BCE. After Egypt, in the 4th Century, variola is thought to have spread to China, where people prayed to the god Yo Hoa Long to try to prevent themselves getting sick, of course, this was to no prevail. After spreading to China, because of the increasing trade with Japan and Korea, smallpox spread even further. This deadly pathogen spread quickly, as somebody only needed to be breathed on, and they could be infected. During the 7th century, smallpox was widespread throughout India and was quickly spreading towards northern Africa, Spain, and Portugal because of the expansion of Arabic people. 300 years later, in the 10th century, variola crept into Asia Minor and modern-day Portugal. During the Crusades in the 11th century, smallpox spread further throughout Europe and infect many more unsuspecting people. Smallpox spreads to northern England, which was previously not affected by this deadly disease. When Smallpox spread to Northern England, it caused multiple outbreaks that traveled as far north as Iceland. Smallpox at this point had already killed people from Egypt all the way to Northern Europe and was not stopping there. In the 15th-16th Century, smallpox was spread through Portuguese traders into Africa. European colonization and the African slave trade spread Variola
Smallpox is an infectious virus that has influenced people for many centuries. Smallpox got its name from a latin word called ¨spotted¨ since you get those bumps that are red all over your body. You could easily prevent this disease.
The brutal symptoms of smallpox reveal why the disease is known as one one of the deadliest in history. Smallpox slowly deteriorates the victim in distinct symptom stages. Symptoms begin to display after approximately ten days since the victim was exposed to the Variola virus. Suddenly, the victim will feel flu-like symptoms including headache, fever, overall discomfort, severe back pain, vomiting, and severe fatigue (“Smallpox.”). Brutal symptoms such as these, unfortunately, are only the beginning for a terrible disease such as smallpox. Next, symptoms become much more visible. After a day or two the forearms, face, and hands will develop flat, red spots. Red spots will eventually develop into small to moderate blisters which are
Imagine a quick spreading rash throughout the entire body, leaving not a single space behind; every opening and crevice in your body, including your mouth and eyes covered in painful bumps accompanied by high fever and severe body aches. Flat red spots transforming into fluid-filled lesions and soon oozing out yellow pus, evidently emitting a pungent odor to anyone who dared get close. The live virus present in the darkening crusty scabs that would soon fall off only to leave behind a deep pitted scarred filled complexion on anyone who was fortunate enough to survive. These scars would be forever remembered as the hallmark for the smallpox epidemic which tormented the world for over 3,000 years. (Riedel “Deadly Diseases”).
In order for this disease to spread among individuals, a non-immune person must come in close contact with an infected individual that was infected less than two weeks prior. Throughout history, persistent migrations also aided the spread of smallpox. Many
This deadly infectious disease is caused by either of two viruses, Variola major and Variola minor which were highly contagious. After exposure symptoms include fever, tiredness, headaches, and muscle aches. This is normally followed by rash or lesions that appear all over the body and face becoming raised with fluid/pus. Smallpox is highly contagious and can be transmitted through bodily fluid, close contact and even clothing/bedding material that came in contact with an infected person.