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Huntington's Disease Analysis

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Researchers looked the chromosomes of more than 4,000 Huntington's malady patients and found that DNA repair qualities may focus when the neurological manifestations start. Incompletely subsidized by the National Institutes of Health, the outcomes may give a manual for finding new medications for Huntington's ailment and a guide for examining other neurological issue. Huntington's disease is an acquired neurodegenerative issue brought on by transformations in a quality that encodes a protein called Huntingtin. Indications of the disease normally start in your midlife and incorporate uncontrolled developments, enthusiastic aggravations and, in the long run, dementia. Despite the fact that studies in people and creatures have found pieces of…show more content…
The author states got one person in every 10,000 in the United States gets Huntington's disease. The symptoms are usually begin with minor arm jerks and some facial twitches. Then following these symptoms tremors spread to various parts of the body and then it develops into writhing. People start to lose the ability to learn or improve motor skills. Basically what is going on in the brain is, "the output from the basal ganglia is inhibitory to the thalamus, and damage to the basal ganglia leads to increased activity in motor areas of the Thelma's. This increase produces the involuntary jerking movements." People with Huntington's disease suffer from psychological disorders as well. Sometimes in the early stages of Huntington's disease people are misdiagnose with having schizophrenia. The book also shows a picture of a normal person's brain and a person’s brain with Huntington's disease, the ventricles expanded because of the loss of neurons; therefore the ventricle looks much larger than it actually is, and it is very evident in the picture (Page 255). Last there is a procedure which enables physicians to predict who or who will not get Huntington disease. To determine this, physicians can count the number of consecutive repeats on the combination C-A-G on one gene on chromosome four. In saying this if the number is fewer than thirty-six, the person will not develop Huntington's disease. Although there are several promising drugs currently in various stages of investigation but none of them have been approved for human use, they have only been tested on animals. I personally think that this needs to be something researchers focus on so we can help the people that are suffering from this terrible
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