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Igor Pogribny Essay

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The National Center for Toxicological Research recommends Igor Pogribny, M.D., Ph.D., Research Biologist of the Division of Biochemical Toxicology, for appointment in the Senior Biomedical Research Service (SBRS) under Biomedical Research category. Dr. Pogribny’s career began in the former Soviet Union, where he received his basic education, followed by M.D. and Ph.D. degrees. His major area of interest was the study of biochemical and molecular mechanisms that led to cancer cell transformation. Since 1992, Dr. Pogribny has continued his research in the United States, and has focused on the biochemical and molecular mechanisms of carcinogenesis. During 30-year research career, Dr. Pogribny has continued to publish the results of his research in peer-reviewed journals and to present his work at national and international scientific meetings. His productivity is demonstrated by a total of 329 publications and presentations. He is the corresponding author of 35 of the manuscripts. His articles have been cited more than 10,500 times with the h-index of 58 according to the Google Scholar website. Dr. Pogribny serves as the principal investigator and co-principal investigator on several approved NCTR …show more content…

Therefore, evaluating the hazard risk of chemical agents continues to remain important. Recognition of the fundamental role of epigenetic mechanisms in the development of major exposure-related human diseases suggests that epigenetic alterations may represent a class of biomarkers with great potential in the identification of exposure status, damage response, and/or disease state and be an essential tool for hazard identification, particularly for non-genotoxic and non-receptor-mediated agents regulated by the

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