Introduction Hepatitis is a disease with a significant global impact. According to the World Health

This research paper is going to review today’s silent killer, the Hepatitis C virus. This paper will talk about the description of the disease, the signs and symptoms, the etiology and risk factors, diagnostic studies, treatments and prognosis of this disease. I had lived with this disease for over ten years before diagnosed so it is important to understand the signs and symptoms so the disease can be identified and a treatment plan can be identified as the sooner it is treated the more likely it will eradicate the disease.

About 4.1 million people in Americans have the positive antibody to hepatitis C virus (HCV), and about 75 percent have permeant infection. Additionally, most of the infections happened 20 to 40 years ago, before the finding of HCV. Hepatitis C increased from 7,000 to 13,000 deaths in 2005. Furthermore, HCV develops slowly which increases the risk of severe complications in the infected people. Identification, death, and treatment are predicted to affect 35,000 by 2030. The Center for Disease Control (CDC) used antiviral therapy with PEGylated in clinical trials (Kalichman, Washington, Kegler, Grebler, Kalichman, Cherry, & Eaton, 2015). The CDC recommends a HCV one time test for people born between 1945 and 1965. The objective of this study was to thoroughly evaluate the amount of substance abusers infected with hepatitis C in the United States. Additionally, to observe the treatment of HCV. Currently Medicaid and Medicare repayment standards for sofosbuvir were calculated in all states, including the District of Columbia. Medicaid and Medicare covered the drug based on the following conditions; liver disease stage, HIV, and drug use. Approximately 42 states reimbursed the following criteria up to 74 percent for the drug sofobuvir. About two-thirds of the United States restricted the treatment centered on prescriber type. About 88 percent included drug abuse in their sofosbuvir admissibility measures. Finally, 50 percent required a date of abstinence and 64 percent required

About 4.1 million people in Americans have the positive antibody for hepatitis C virus (HCV), and about 75% of them are persistently infected and most of the infections happened d 20 to 40 years ago, before the finding of HCV. Hepatitis C increased from 7,000 to 13,000 deaths in 2005. Furthermore, HCV develops slowly which increases the risk for severe complications in the infected people. Identification, death, and treatment is predicted to affect 35,000 by 2030. The Center for Disease Control (CDC) used antiviral therapy with PEGylated in clinical trials. The CDC recommends a HVC one time test for people born between 1945 and 1965.They observed testing by birth. The objective of this study was to thoroughly evaluate the amount of substance abuser infected with hepatitis C in the United States. Additional to observe the treatment of HVC. Currently Medicaid and Medicare repayment standards for sofosbuvir were calculated in all states including the District of Columbia. Medicaid and Medicare covered the drug based on the following classes liver disease stage, HIV, and drug use. Approximately 42 states reimbursed the following criteria up to 74% for the drug sofobuvir. About two thirds of the United States restricted the treatment centered on prescriber type. About 88% included drug abuse in their sofosbuvir admissibility measures. Finally 50% required a dated of abstinence and 64% required drug test. The latest drug to HVC is called Sovaldi and it costs $84,000 for the 12

The hepatitis C virus is a single-stranded RNA virus of the Flaviviridae family. The virus replicates within hepatocytes and is most notable for lacking a proofreading polymerase which enables copious amounts of viral mutations. There are 6 genotypes of HCV with the most widely distributed genotypes being types 1, the most common, and type 2.

In general, a patient is infected with only one hepatitis C virus genotype. The strain of genotypes is not differentiated by the severity of the disease. However, there will make a distinction in the regimen and the duration of the treatment (CDC, 2016). Treatment for chronic HCV is based on guidelines from the Infectious Diseases Society of America (IDSA) and the American Associations for the Study of Liver Diseases (AASLD). The criteria of who should receive the treatment include how much the virus in the body, the strain of hepatitis C, the degree of liver inflammation or damage, comorbidity, and response to previous treatment (Infectious Diseases Society of America [IDSA], 2016). The highest priority for treatment should give to a patient with advanced fibrosis and compensated cirrhosis (IDSA, 2016). Moreover, treatment priority should provide to the patient who has a high risk of transmitting the disease from and to others, such as individuals who are active injection drug users and hemodialysis patients (IDSA, 2016).

When a doctor uses the term Hepatitis C or HCV, what comes to mind? Many people have little to no knowledge of what it is. Is it deadly? Is there a cure? Is it a virus or disease? There are many questions that enter the mind because there are many concerns associated with an unknown illness. Several people wonder if the virus is similar to hepatitis A or B because there has been education throughout the years that provides more awareness surrounding the two known viruses, but it is discovered there are vast differences. Until recently, the general population was unaware that another hepatitis virus acted as a silent killer. Unlike hepatitis A or B, hepatitis C is a relatively new disease that can go unnoticed until it is too late. The virus

Hepatitis is a viral disease that damages and affects liver. There are three type of hepatitis, simply known as: hepatitis A(HAV),B(HBV) and (HCV).The article explores some of the key basic elements a person needs to know to fight hepatitis disease.

Hepatitis is a disease caused by a virus that is characterized by liver inflammation. There are three common types of hepatitis – A, B, and C. “Over the past 15 years the incidences of hepatitis and b virus infection in the US have declined significantly. By contrast, the incidence of hepatitis C, formally stable or in decline, has increased 75% since 2010”. (Dan, 2015)

The infectious disease known as Hepatitis is caused by the infectious agent or pathogen identified as the Hepatitis A virus. There are currently seven known forms of Hepatitis, such as Hepatitis A, Hepatitis B, Hepatitis C, and so on. Hepatitis A, Hepatitis B, and Hepatitis C are the most common with the highest rate of people contracted with the infectious disease. Viral Hepatitis is an international main contributor to liver disease and accounts for high illness and death. In the United States Hepatitis A, HAV for short has reached a massive decline of occurrences since vaccinations became available. The decrease in incidences has nearly hit ninety percent. Though, there are still over twenty five thousand people

“According to WebMD, 3.2 million people in the United States of America are affected by this disease. It is transmitted through bodily fluids, such as, blood, semen, saliva, sweat, and sexual contact. Additionally, it can be transmitted through the sharing of needles and drugs, unprotected sex, and it can be passed mother to baby through birth (Hepatitis C: Treatment and Care 1). People with this strand of the disease usually have no known symptoms, however, some may occur including jaundice, stomach pain, loss of appetite, Nausea, and fatigue. Treatment is from a variety of antibiotics including Daklinza, Harvoni, Technivie, and Viekira Pak. However, dangers can arise from the antibiotics Technivie and Viekira Pak causing severe liver damage. The following people should get tested for this strand of the disease; if you’ve received blood from a donor, if you’ve ever injected drugs, got a blood transfusion or organ transplant, or if you’ve ever had long term kidney dialysis (Hepatitis C: Treatment and Care

Hepatitis C is a liver infection caused by the Hepatitis C virus (HCV). Hepatitis C is a blood-borne virus. Today, most people become infected with the Hepatitis C virus by sharing needles or other equipment to inject drugs. For some people, hepatitis C is a short-term illness but for 70%–85% of people who become infected with Hepatitis C, it becomes a long-term, chronic infection. Chronic Hepatitis C is a serious disease than can result in long-term health problems, even death. The majority of infected persons might not be aware of their infection because they are not clinically ill. There is no vaccine for Hepatitis C. The best way to prevent Hepatitis C is by avoiding behaviors that can spread the disease, especially injecting drugs.

Although we are well aware of the mode of transmission, the hepatitis C virus itself remains a mystery. The genome of HCV is extremely mutable. Because HCV is an RNA virus and does not have adequate proofreading ability as it replicates, virions infecting humans undergo evolution with time, giving rise to the notion that HCV persists as a collection of virus quasispecies. Because it is constantly mutating, HCV is able to escape detection and elimination its human host. HCV undergoes quick mutation in a hypervariable region of the genome coding for the envelope proteins and escapes immune surveillance by the host. As a result, most HCV-infected people develop chronic infection. HCV also knocks out the host’s innate immunity.

Hepatitis C is an inflammation of the liver’s cells and tissues caused by the hepatitis C virus (HCV).

The diagnosis of HCV infection is established with an immunological test followed by viral RNA detection using a qualitative molecular method. In addition, quantification of viral RNA and HCV genotyping are useful for follow-up of patients on treatment.

During the course of many years, there have been a lot of diseases that caused significant effects on the people. Some of those diseases are Ebola, AIDS, plague, and small pox. But I bet you didn’t know that Hepatitis is one of them. Hepatitis means injury to the liver with inflammation of the liver cells. In doing my research, I have found six different types of hepatitis. They are Hepatitis A, B, C, D, E, and G. All of these end up causing disease except for Hepatitis G, which just lives in the blood and does not cause the person who is infected to show signs of any illness. Hepatitis A, B, and C are the most common ones and are usually the only ones that people know anything about.