Leukemia
Leukeumia is a type of cancer affecting the bone marrow. Bone marrow is where platelets, red blood cells and white blood cells (Leukocytes) are made. (Medical Journal Dictionary)Leukemia is caused by the rapid production (Proliferation) of Leukocytes, and causes a build-up that inhibits red blood cells, and platelets from functioning and stops other Leukocytes from fighting infection. Because of the abnormally rapid production these cells are unable to mature or develop properly and are unable to carry out their functions. (Almeida & Barry, 2010) There are four main types of Leukemia, each classified by how rapid the disease develops and which type of white blood cell is affected; Acute which is a rapid
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(MedicineNet)
Transfusions and Antibiotics
There are two types of transfusions given to a patient with Leukemia; blood transfusions which help to relieve Anemia, and platelet transfusions which help to promote clotting and prevent bleeding. Antibiotics are also given to fight off any infections the patient cannot fight off independently.
Targeted Therapy and Immunotherapy
Targeted therapy uses drugs to kill only the cancer cells without harming normal cells. A specific type of Target therapy is Monoclonal Antibody Therapy. Antibodies are formed in a laboratory that can identify substances that help in the formation of cancer cells. When the antibody recognizes the substance it attaches itself to it and can kill the cancer cells, block their growth or keep them from spreading. The antibodies can also be used to carry drugs, toxins or radioactive material straight to the cancer cells. Just like Targeted Therapy, Immunotherapy blocks the growth and spread of cancer cells, but instead uses the body’s own immune system. These two therapies are often used in combination with Chemotherapy and other treatments.(The National
Cancer Institution, 2011) (What is the goal of treating indolent B-cell NHL?, 2011)
Treatments for Chronic Leukemia
Chemotherapy
Chemotherapy is the most common treatment for all types of cancer. Chemotherapy stops the production of
There are many different type of cancers, there are also many different types of treatments. One of the most known types of treatments would be chemotherapy. Chemotherapy can be used for a wide range of different types of cancers and diseases, and each of the different types of cancers or diseases require a different group, and sometimes order, of chemicals to properly treat the cancer or disease. These chemicals include: Alkylating agents, Antimetabolites, Anthracyclines, Topoisomerase inhibitors, mitotic inhibitors, corticosteroids, and more. Each of these drugs previously listed have its own cancer type(s) or disease(s) that it can assist in treating. Some of these cancers include: Leukemia, Lymphoma, Hodgkin disease, multiple
Scenario: John is a 4 year-old boy who was admitted for chemotherapy following diagnosis of acute lymphoblastic leukemia (ALL). He had a white blood cell count of 250,000. Clinical presentation included loss of appetite, easily bruised, gum bleeding, and fatigue. Physical examination revealed marked splenomegaly, pale skin color, temperature of 102°F, and upper abdomen tenderness along with nonspecific arthralgia.
Leukemia is cancerous disease that starts in blood-forming tissue such as the bone marrow and causes large numbers of blood cells to be produced and enter the blood-stream (National Cancer Institute, 2008, para. 1). It is one of many complicated cancer diseases that affect all ages and have very negative outcomes if not treated properly, and on time. Within the disease are several different types that affect according to how quickly the disease develops and attacks the body. It could be classified as chronic leukemia, which has a slow progress of getting worse or acute leukemia which usually gets worse quickly. The types of leukemia also can be grouped based on the white blood cell that is affected (National Cancer Institute , 2008, p. 1).
1. Chemotherapy is frequently used for childhood cancer because what it does is it stops the cancer cells from growing either by stopping the division of the cells or by killing them. (Bernard, Samantha C. et al., 2017)
Leukemia broadly describes conditions that affect erythropoiesis in the bone marrow, lymphatic system, and spleen. As with all other cancers, leukemia begins from the mutation of DNA in certain cells. Classifications of leukemias are based on the age of onset and the leukocyte involved (Lewis et al. 2014, 665). The most common leukemia is chronic lymphocytic leukemia (CLL), accounting for approximately 30% of cases in the United States (Copstead and Banasik 2013, 222). The normal function of the bone marrow, spleen, and liver becomes interrupted by the invasion of malignant lymphocytes (B cells); since the B cells are functionally inactive, a patient becomes more susceptible to infections. The sluggish progression of CLL unfortunately leads to late diagnoses and poor prognosis (Lewis et al. 2014, 665). Patients that become symptomatic in later stages will experience fatigue, weight loss, anorexia, and an increased susceptibility to infection, due to abnormal antibody production. Patient specific factors such as age, disease progression, and medication side effects will determine the course of treatment (Copstead and Banasik 2013, 223). The fragile state of patients with CLL requires continuous examination of drug therapy and interventions to prevent further complications.
Leukemia is a type of cancer that sadly causes around 25,000 deaths in the U.S. each year. The area that it affects is the blood and the bone marrow and like most or all of the types of cancer in the world if not taken control of early it will most likely kill you.
They may be applied to bloodstream or directly to a cancer site. Chemotherapy typically refers to the destruction of cancer cells, however some may include antibiotics or other medications to cure an illness or infection. Often, chemo is used alongside other treatments. Physical activity is important and it’s been found that patients who regularly exercise after chemotherapy treatment have a much lower risk of cancer recurrence. Chemotherapy generally has 5 goals; total remission, combination therapy, delay/prevent reoccurrence, slow down cancer progression and relieve cancer symptoms. The objective is to prevent cell division using cytotoxic drugs, to target cancer cells food source, enzymes and hormones that they need in order to grow, and to stop the growth of new blood vessels that supply the tumor. Patients can either receive monotherapy where they’re just given one drug, or combination where the patient receives more than one drug. These courses of chemo can be just a one day treatment or last for a few weeks, it depends on the type and stage of the cancer basically how advanced it
Thesis/argument statement OR main idea statement: Cancer affects children and their families in many ways.
* Chemotherapy: Using special medicines or drugs to shrink or kill the cancer, Drugs include pills or IV. (Maybe both)
Leukemia is a cancer that affects the bone marrow. The bon marrow is the soft spongy center of the bone that produces blood cells. Leukemia is found in white blood cells or leukocytes. The white blood cells help to fight ff infections and other diseases. Normally, cells produce in an orderly way, but people that have leukemia the cell production gets out of control. The marrow produces too many immature white blood cells called blasts. They are differently shaped and can’t carry out their usual duties.
Cancer can’t be cured, but it may be controlled for a time by chemotherapy. Its goal is to stop or slow down the growth of a tumor or shrink it at least partially or to decrease any pain, bleeding, abstractions
Therefore, dose and duration of treatment is limited, which in turn limits the amount of normal and tumor cell death. A second mechanism is the suppression of cancer cells for variable periods of time without cell death. This mechanism is referred to as remission. Unfortunately, the cancer can return at any time, and it is sometimes stronger. Here another limitation is introduced. Some tumor cells can develop resistance to a particular chemical agent, or several chemical agents, limiting the types of chemotherapeutic agents available for effective use. The last mechanism is cell differentiation, which helps the immune system learn to recognize and fight tumor cells (1).
Chemotherapy, Radiation therapy, stem cell transplant, and targeted drug therapy are all forms of treatment for ALL. Chemotherapy is typically used as induction therapy for kids and adults. Chemotherapy can also be used in consolidation and maintenance therapies. Chemotherapy is given in a variety of ways. It can be given orally as a pill or liquid. It can be given intravenously by infusion into a vein. A cream on the skin can be given. Chemotherapy can also be given by direct placement either via lumbar puncture or a device placed just under the scalp. Radiation therapy uses high-powered beams, such as x-rays, to kill the cancer cells. Radiation therapy is usually recommended when the cancer has spread to the central nervous
Leukemia is something that we hear about a lot. I believe that people do not understand exactly what leukemia is and how dangerous it can be, I chose this topic to try to help them understand. In this paper I will explain what leukemia is and what treatments you can choose from to treat the cancer.
There are two types of leukemia in children; acute and chronic. Acute is fast growing leukemia. Within acute leukemia are three categories: acute lymphocytic (lymphoblastic) leukemia (ALL), acute myelogenous leukemia (AML), and hybrid or mixed lineage leukemia. Acute lymphocytic (lymphoblastic) leukemia (ALL) is the most common type of childhood leukemia and develop from early forms of lymphocytes, also known as white blood cells. Specifically, three out of four childhood leukemias are ALL (About Childhood Leukemia). Acute myelogenous leukemia (AML) starts from the myeloid cells that create blood forming cells such as white blood cells (except for lymphocytes), red blood cells, and platelets (About Childhood Leukemia). Hybrid or mixed lineage leukemia are rare forms of childhood leukemia, but can be treated like ALL and AML. On the other end of the spectrum is chronic, or slow growing, leukemia. Chronic leukemia is difficult to treat and are more commonly found in adults than children. There are two types of chronic leukemia: chronic myelogenous leukemia (CML) and chronic lymphocytic leukemia (CLL). Chronic myelogenous leukemia (CML) is not commonly