Lhon Research Paper

One reason I would like to be apart of H.O.P.E is because it has been a dream of mine to help/lead other’s. I would also like to join so that I can help other students

Reach Out with a question to the NCU Librarian. Explain your question and answer you received and how that facilitated your used of the NCU Library.

People are more aware about their fat burning, energy boosting and etc. From model to bodybuilders, everyday working professionals who want to achieve cutting, searching for body supplements. A person who wants to begin intake of this supplement should be consistent on understanding the benefits. Clen is a formulated injectable treatment designed to achieve various health related issues like breathing disorders, asthma and etc. The primary purpose of clen is to increase the beta 2 receptors. When this occurs, the internal body temperature will be increased by boosting the cellular heat. This takes place inside of cellular mitochondria. The cells are more responsible for heat production inside of the body.

As a result of retinal haemorrhages, children can suffer with permanent damage to their vision due to the inflicted injury to the eye or the brain. Scarring of the retina or atrophy of the optic nerve may show up months after the injury, and is frequently irreversible. This can result in the infant suffering with severe vision impairments and even blindness (Blumenthal, 2002).

Pupils equal and round, reactive to light. Wears glasses, had injury to eye in 2008 where traumatic Cataract removed and lens was implanted.

Visual imparity is one of the biggest epidemics in the modern world affecting an estimated 285 million people worldwide (WHO, 2014). Of theses 285 million people, roughly 39 million of them are completely blind. Blindness is a ‘debilitating sensory impairment’ according to Lorach(2014), which can limit a person’s ability to perform everyday tasks and can hugely affect their quality of life. Most of the diseases causing visual impairments, such as cataract can be surgically treated. However, some pathologies cannot be treated with existing treatments or medications. Retinitis pigmenstosa (RP) is an example of such pathology. RP is an inherited eye disorder in which light-receiving photoreceptor cells (rods and cons) degenerate. The photoreceptor

Kirches conducted a case study in which the hereditary movement of LHONs was observed. In this study, it was found that LHONs can cause an acute loss of retinal ganglion cells and their axons. According to this study “RGC loss occurs in about 50% of male and only 10-15% of female mutation carriers” this shows evidence that men are more effected by LHONs it also shows why women do not show symptoms of LHONs (Kirches 2011 n.pg). Showing the true causes of blindness presented with

For example, Absence of color in the hair, skin or eyes. Lighter than normal coloring of the hair, skin or eyes. Or patches of skin with absence of color. Conditions of the eyes is primarily the main concern for people with albinism. These conditions are not correctable with lenses. Some people experience, astigmatisms, impaired vision or blindness, nystagmus (involuntary rapid eye movements), photophobia (sensitivity to light) and strabismus which is cross eyes. Taking an electroretinogram test can measure the response of light sensitive cells in the eyes to reveal complications of

Hereditary retinal diseases are a heterogenic group of diseases that cause impaired vision and even blindness, due to damage to the eye's light receptors- the photo-receptors. These diseases include Stargardt Diseases, cone-rod dystrophy and Leber Congenital Amaurosis.

While vision loss is often associated with aging. In fact, according to the American Association for the Blind, more than 6.5 million Americans over 65 have a severe visual impairment. It is not enough to know that there is a problem, however, it is important to know why the vision loss is taking place. Once you understand the underlying cause, steps can be taken to repair or at least protect the eyes. The biggest problem with vision loss is that many of the most serious conditions are not noticed until damage has already been done.

Tumors, that can apply a pressure on the optic nerve causing various forms of visual loss.

A lesion that destroys the optic nerve will destroy all input from that retina, leading to monocular visual loss (blindness in that eye).

Vision challenge or impairment is when a person’s degree of seeing is very low and the affected person requires assistance in order to carry out daily routine. Significantly, for one to qualify as visually impaired there must be prove that a person cannot undertake duties by himself without necessary assistance. For a person to qualify as a visually challenged, there must be a prove that the affected eyes cannot be conventionally treated. Visual challenge cannot be corrected by surgery, refractive measures neither by medication and that is why it is termed as visual impairment. The most rampart causes of visual challenge are trauma, degenerative or congenital means and a variety of diseases. In the society,

Leber’s Hereditary Optic Neuropathy (LHON) is a disease caused by a point mutation in the mitochondrial genome, it is maternally inherited and largely affects males of young ages.1 LHON presents acutely or subacutely in affected individuals, the age of disease onset or vision loss is usually between the ages of 8 to 60 years.2 The onset of LHON involves the loss of central vision in affected individuals, sometimes bilateral central vision loss.1 Leber’s Hereditary Optic Neuropathy can affect one eye first and can gradually affect both eyes, there can be a total loss of vision or progressively over approximately 3.7 months.2 Among the mutations causing Leber’s Hereditary Optic Neuropathy, mutation np 11778 or LHON11778A is the most severe and common. 2According to The clinical characteristics of pedigrees of Leber 's hereditary optic neuropathy with the 11778 mutation, by NJ Newman, affected individuals with this particular mutation had visual acuities of 20/200 or poorer in approximately 98% of eyes screened in the study.2

We can tolerate very large scars on our bodies with no concern except for our health. This is not so in the cornea. Even a minor scar or irregularity in the shape can impair vision. No matter how well the rest of the eye is functioning, if the cornea is scarred, clouded or distorted, vision will be affected. This can be caused from any sort of retinal degenerative disease like macular degeneration. This is when the front-end cells die, the photoreceptors die, and over time, all the cells and the circuits that are connected to them, they die too. Until the only things that you have left are these cells here, the output cells, the ones that send the signals to the brain, but because of all that degeneration they aren 't sending any signals anymore. They aren 't getting any input, so the person 's brain no longer gets any visual information, thus causing blindness. These diseases can be genetic but can be caused accidents.