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Nicotine Research Paper

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The negative health effects of tobacco use have been well established. Tobacco use has been shown to cause acute and chronic respiratory disease, heart disease, many types of cancer, and is the leading cause of preventable morbidity and mortality in the United States, causing an estimated 443,000 deaths per year (U.S. Department of Health and Human Services 2004). As the dangers of smoking have become better understood, reducing the number of people who smoke has become a major focus for those interested in public health. Efforts to restrict the advertisement and sale of tobacco, implement public smoking bans, and educate citizens through public service announcements have all had a sizeable effect on smoking rates in the U.S. In Fact, over …show more content…

Nicotine, the primary psychoactive chemical in tobacco, is a very powerful drug. When nicotine enters the body, it travels through the bloodstream to bind with nicotinic acetylcholine receptors throughout the body and brain, causing physiological and psychological changes in functioning. Among the many effects nicotine has in the body, perhaps its most powerful is its ability to stimulate the release of dopamine in the mesolimbic dopaminergic pathway. It is thought that increased levels of dopamine in the brain are a major contributor to the euphoric, relaxing, and addictive properties of nicotine (Fagerstom et al. 1990). It has been proposed that this effect might be especially powerful and rewarding to individuals who suffer from mental illnesses caused by dysfunctions in the dopamine system, like schizophrenia, depression, and addictive disorders (Maté 2010). For these people, the burst of dopamine cause by ingesting nicotine could be having a more powerful effect, making it more addictive. This same mechanism could also explain why attempting to quit smoking, and thereby further upsetting an already unbalanced dopamine response, could be especially difficult for people with a mental …show more content…

The crux of this proposed relationship is simple; if one is in a state of chronic stress, anxiety, or agitation, a brief respite from these negative feelings is more psychologically rewarding than it would be to someone who is not. This could also lead people with a mental illness to be more negatively affected by nicotine withdrawal. People who suffer from panic attacks, for instance, might find it harder to quit smoking because some of the symptoms of nicotine withdrawal (such as racing thoughts and increased heart rate) could trigger a panic attack (Centers for Disease Control and Prevention 2013). Understanding the powerful combination of these biological, social, and psychological factors has caused some to wonder if it is even possible to lower the rate of tobacco use among people with a mental illness. Interestingly, many behavioral health and medical professionals actually question whether they should even advise their patients with psychiatric disorders to quit at all, fearing that quitting might make their psychiatric symptoms worse. These concerns seem to be almost entirely contradicted by growing body of research investigating smoking and mental

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