Opioid Manufacture: A Case Study

Mike Alstott knows first-hand how opioids, when used correctly, can play an important role in managing pain and helping people to function, but he is also keenly aware of the growing crisis of opioid misuse and overdose. More American adults are dying from misusing prescription narcotics than ever before. An estimated 35 people die every day in the U.S. from accidental prescription painkiller overdoses resulting from things like not taking a medication as directed or not understanding how multiple

In fact, there was thought to be more of a need for them. Before the last two decades, opioids were used for cancer related or acute pain. However, in the 1990s chronic non cancer patients got attention because people nationally felt there was a shortage in patients receiving opioids, thus making them deprived of adequate pain management. Because of this, clinicians were encouraged to treat chronic non-cancer pain and patients in hospice care more often than they were used to. It was also encouraged to use high doses of opioids for long periods of time (Cheatle). The idea that providers seemed overly cautious about these medications caused a large increase in opioid prescriptions from health care providers. Threat of tort and litigation for some doctors that were deemed for not prescribing enough to alleviate pain of patients was also a concern for doctors This quickly turned a shortage of prescription opioids into a national prescription opioid abuse epidemic in under twenty years. From 1999 to 2010, the amount of prescription opioids sold to hospitals, pharmacies, and doctors offices quadrupled, and three times the number of people overdosed on painkillers in this time (Garcia). While some patients have benefitted from the increased sales and loose guidelines of prescription opioid analgesics, the increasing in opioid misuse, abuse, and overdose is truly daunting. As a nation, we need to back track, and

Opioid addiction is a condition that is preventable as well as one which individuals display several noticeable risk factors before the actual addiction prognosis to the point of causing death. There is a strong correlation between the early misuse of prescription opioids, which are prescribed for non-cancer pain management, and the development of a dependence on such opioids. Early detection of risk factors such as the misuse of opioids that are prescribed will help indicate that a patient is developing an addiction.1 Physicians, nurses, pharmacists, and other healthcare providers must closely monitor patients and the rate at which opioids are consumed as well as refilled.

Opioid use has to begin somewhere. Patients that are prescribed opioids for pain treatment run a risk of developing dependency on the prescribed medications. Numerous individuals who take the opioids for extended amounts of time may begin to progress towards higher tolerances of the prescribed medicines. Due to this higher tolerance, individuals may feel like they need to take more than what was prescribed. Eventually this can lead to craving opioids in order to function or to “feel better” throughout the day. In fact, it has been estimated that between twenty-one and twenty-nine percent of patients that are prescribed opioids for chronic pain misuse them and close to ten percent develop an opioid use disorder (https://www.drugabuse.gov/drugs-abuse/opioids/opioid-overdose-crisis, 2017). “Some people experience a euphoric response to opioid medications, and it is common that people misusing opioids try to intensify their experience by snorting or injecting them” (https://www.samhsa.gov/disorders/substance-use, 2015). This means of drug intake, generally leads to the exploration of more easily acquired drugs with stronger effects.

As better and more comprehensive education is provided both to the general public and practicing clinicians the hope is to reduce the negativity surrounding the users of opioids, and to eliminate demeaning language coupled to them as well. This could improve patient morale and help the needless continuation of physical suffering within patients, as they would be more comfortable approaching and using opioids for therapeutic purposes1. That being said there are those within our communities who do abuse these substances and pharmacists must recognize the signs of abusers, it is important for them to reach out, without comment, to help those suffering from opioid abuse once they have been

These drugs are easy to become addicted to and continued use could lead to dependency. Citizen have to be sure to take drugs only prescribe to the patient on the bottle because what is safe to one person might not be to someone else. This is because our body chemistry is different for everyone.Some people are tricked into thinking it's safe because they are prescribed by doctors.This is untrue and opioid are very dangerous when taken recreational. Most opioids are given to help get through serious injuries. When you start these drugs, you can expect to experience drowsiness, slowed breathing, and constipation. The drug also will relieve the pain it was prescribed for. If long term usage occurs the user can easily become addicted. The body get used to the presence of these drugs and becomes attached. They might even need to use higher dosages to achieve the same high because the body builds up tolerance. This is how people overdose. The opioids slows the breathing so much that that stop breathing at

Opioid-induced adverse effects are a very interesting topic and does play a big part in patient safety. It’s estimated that more than half of older adults who reside in a healcre related community have a chronic pain disorder, with the long-term care setting rate of prevalence substantially increased (up to almost 90%). Physicians across all care settings are tasked with the daunting challenge of providing pain relief while, at the same time, minimizing opioid-induced side effects. Some of the common opioid-induced side effects are Constipation, Nausea, Vomiting, Pruritus, Sweating, Sedation, Fatigue, Headache, Delirium, Confusion, Clouded vision, Dizziness, Xerostomia, Postural Hypotension, Bladder Dysfunction such as Urinary Retention,

Opioids, otherwise known as prescription pain medication, are used to treat acute and chronic pain. They are the most powerful pain relievers known. When taken as directed they can be safe and effective at managing pain, however, opioids can be highly addictive. Ease of access helps people get pain medications through their physician or by having friends and family get the medication for them. With their ease of access and being highly addictive the use and misuse of opioids have become a growing epidemic. Patients should be well educated on the affects opioid use can have. More importantly instead of the use of opioids, physicians should look into alternative solutions for pain management. While pain medication is helpful with chronic pain, it is also highly addictive, doctors should be more stringent to whom and how often they prescribe pain medication.

The use of opioid-based prescription medications to treat non-terminal chronic pain can cause side effects from short term use, and is overly common and ineffective. Firstly, opioid usage can induce negative short-term effects. According to William A. Darity, Jr., short-term opioid usage causes negative effects such as “euphoria, drowsiness, and impaired motor and cognitive functioning” (“Drugs”). The short term effects of the opioids may cause the patient to isolate him or herself socially due to being self-conscious about his or her friends and peers seeing the individual in their current condition. Due to his or her fragile emotional state, however, if the patient isolates him or herself during a time in which he or she should have increased

When opioids are used chronically, tolerance and dependence can occur and the side effects differ depending on the substance, as does the abuse potential (Addiction.com, 2011) (Steven A. Adelman, William J. Meehan, 2010). Combining or improper use of opioid medication with other prescription or over the counter medication could be fatal (CAMH, 2010) (Canada, 2009).

Opioid pain medicines are strong medicines that are used to treat serious pain. Only take these medicines while you are working with a doctor. You should only take them for short amounts of time.

The opioid crisis has been gradually increasing since the discovery of opioids as pain management medication by pain specialists in the 1980s. If the crisis is not mitigated, more people are likely to suffer the consequence of the effects of addiction and overdosage, given the highly addictive nature of opioids. Mitigating the crisis requires collaborative efforts, particularly from clinical prescribers and drug manufacturers who need to recognize that these drugs are potentially harmful when used repeatedly and misused. Physical therapy is an alternative mitigation measure in handling chronic pain. Evidence shows significant success rates among patients who have chosen the physical therapy route as opposed to the opioid

This is inaccurate because prescribed opioids are still addictive. The truth is that people typically turn to street drugs because they offer the same euphoric and satisfying feeling but at a much cheaper cost. Everyone blames the drug-addicts because it was "their fault". But no one goes deeper than that. The Western ideology that "pills heal all ills" needs to end. In some parts of the U.S., pills are prescribed for almost anything you can think of, and doctors, not wanting to disappoint their patients, give more and more medicine and it is unnecessary.

Domination and slavery were over in Mexico. Mexico was liberated from Spaniards, but the descendants of Spain had a higher power and the Indians and Mexicans had fewer rights and power. Those that govern were the Mestizos. Although Mexicans were already free, the Spaniards left them with nothing and poor. Spaniards took everything; their lives, money, traditions, and most important their dignity. Mexico was left with a lot of territories. Mexico owned what is all of Mexico nowadays and some of the states of the United States. Given the circumstances, United States was also expanding territory at that time and was in the processing of spreading more. Clearly, the governance of Spain and United States have similarities and differences on the

Do you know that Rebecca was the best seller novel sold between 1938 and 1965? The novel was written by Daphne du Maurier in 1938. The story is a mixture of love and hate for the primary characters in Rebecca novel. It begins when a young, poor woman who works with Ms. Van Hopper meets Maxim de Winter. Then the young women, narrator, feels in love with Maxim de Winter and decide to get married to go with him to Manderley. After that she meets Mrs. Danvers and the narrator feels uncomfortable because she seems like a devil woman. The narrator feels deeply frustrate and upset because she thinks Maxim loves Rebecca crazily. Then she founds the secret that Maxim does not love Rebecca, so she becomes better and gets confidence again. Furthermore Maxim meets Dr. Baker and he tells him that Rebecca is not pregnant, but she has had a cancer. In the end, Maxim returns back to Manderley and sees