Physiological Aspects of Juvenile Idiopathic Arthritis
Juvenile idiopathic arthritis (JIA) is an autoimmune disorder characterized by arthritis in in one or more joints for at least six weeks (Prakken, Albani, Martini, 2011). JIA is a chronic condition consisting of swelling in any join in the body and is found in children age 16 years or younger. The peak age of onset is between 1-3 and 8-12 years old. The immune system attacks the body’s synovium, the joint lining, and this inflammation spreads to other parts of the joints.
Symptoms
There are a variety of symptoms that children with JIA experience and they vary depending upon the type of JIA. These symptoms can include morning stiffness, limping, fever, rashes, difficulty with fine motor skills, decreased appetite, weight loss, and fatigue or irritability. The main symptom is pain swelling and tenderness in the joints. The subtypes of JIA are characterized by the amount of joints affected. The subtype where four or less affected joints and there is eye inflammation, is oligoarthritis. Polyarthritis is a type of JIA that affects 5 or more joints in the first 6 months, including the neck, jaw, hands, and feet. Systemic arthritis occurs in 10-20% of children with JIA and affects the whole body system, not solely joints. Psoriatic arthritis affects children with a rash as well as the swollen joints.
Diagnosis and Treatment Diagnosis Diagnosis for JIA is difficult and is a diagnosis of exclusion, which comes from ruling
However, there are cases in which adolescents that may not do as much physical activities also develop this disease. There is no need to worry too much about it though. If you know how it works, you can be assured of
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In my rotation at Georgetown, I sought to explore the field of rheumatology at a tertiary level and in doing so, gained experience in common autoimmune conditions and some rare ones as well all which served to solidify my interest in the field. One of the most pleasant aspects of my duties at Georgetown was the opportunity to work with children. In taking pediatric rheumatology consults, I realized that as a rheumatologist I may be able to care for patients of all age groups, leading to an interesting and highly diversified
Dr. Aguiar, a Brooklyn native, completed her undergraduate studies at Hunter College City University in New York City. She received her medical degree from New York University School of Medicine and completed her residency at New York University Medical Center. In addition, Dr. Aguiar, completed her fellowship in pediatric rheumatology at the Hospital for Special Surgery/ New York Presbyterian-Cornell, in New York City. Dr. Aguiar is board certified by the American Board of Pediatrics in pediatrics and pediatric Rheumatology. She currently is on the faculty at the Children’s Hospital of the King’s Daughters. She has a special interest in Antiphospholipid syndrome, Systemic lupus erythematosus, Vasculitis, Juvenile arthritis, and Musculoskeletal
There are different types of arthritis such as gouty arthritis which causes a swelling usually in the big toe, psoriatic arthritis that often occurs along with psoriasis and reactive arthritis which usually involves the eyes, urethra and joints. Juvenile arthritis is an umbrella term used to describe any form of childhood arthritis or arthritis-related conditions which affects people under 16 years old. The most common form of childhood arthritis is juvenile chronic arthritis (JCA) which is also referred to as juvenile rheumatoid arthritis (JRA). Individuals who suffer from JRA experience stiffness and joint inflammation that result into swelling, warmth, soreness and redness of the joints. JRA, also
Developing this disease made it so that a major shift in my life occurred. When I first heard that the doctor had made a diagnosis of Juvenile Arthritis I didn’t know what to do. I felt like the world around me was coming down on me. I had to learn basic skills all
Rheumatoid arthritis is a chronic syndrome that is characterized by inflammation of the peripheral joints, but it may also involve the lungs, heart, blood vessels, and eyes. The prevalence of this autoimmune disease is between 0.3% to 1.5% of the population in the United States (Feinberg, pp 815). It affects women two to three times more often than men, and the onset of RA is usually between 25 and 50 years of age, but it can occur at any age (Reed, pp 584). RA can be diagnosed by establishing the presence of persistent joint pain, swelling in a symmetric distribution, and prolonged morning stiffness. RA usually affects multiple joints, such as the hands, wrists, knees, elbows, feet, shoulders, hips, and small
Juvenile Rheumatoid Arthritis (JRA) is a chronic and progressive autoimmune disorder of the joints. In JRA the joints become stiff, swollen, and inflamed causing pain and loss of movement. The cause is thought to be genetic and/or related to environmental factors which are still not understood. Because of its origin not being well understood, JRA is also called juvenile idiopathic arthritis. The body has abnormal immune responses wherein it attacks normal cells and tissues causing damage to the joints (McMahon Anne-Marie, 2011).
Juvenile idiopathic arthritis (JIA), previously known as juvenile rheumatoid arthritis (JRA), is an autoinflammatory disease that begins before the age of 16. (2) The cause behind JIA is currently unknown. Symptoms of JIA are a fever (a rash usually accompanying the fever as well), enlarged spleen, presence of arthritis, and also always a sign of systemic inflammation
Rheumatoid Arthritis or (RA) is an autoimmune disease that attacks the joints and connective tissue. The result is inflammation that produces permanent damage in the joints. Rheumatoid arthritis is a chronic syndrome that tends to be progressive and destructive as compared to Osteoarthritis or (OA), which is more of an age related disease caused by “wear and tear” of the joints. In contrast to (OA), rheumatoid arthritis is characterized by inflammation mostly of the joints, but is a general body disease.
Rheumatoid arthritis is a chronic syndrome that is characterized by inflammation of the peripheral joints, but it may also involve the lungs, heart, blood vessels, and eyes. The prevalence of this autoimmune disease is between 0.3% to 1.5% of the population in the United States (Feinberg, pp 815). It affects women two to three times more often than men, and the onset of RA is usually between 25 and 50 years of age, but it can occur at any age (Reed, pp 584). RA can be diagnosed by establishing the presence of persistent joint pain, swelling in a symmetric distribution, and prolonged morning stiffness. RA usually affects multiple joints, such as the hands, wrists, knees, elbows, feet, shoulders, hips, and small hand joints. RA is
A defining moment in my life that has helped shape my dreams and plans was when I was diagnosed with Juvenile Rheumatoid Arthritis. After that I was also diagnosed with an autonomic dysfunction and IBS. I didn’t know what to do, I was scared and confused. I was asking myself, “why did this have to happen to me?” When at doctor’s appointments I would see other boys and girls just like me, same age group, that just gave into the disease. It was then when I realized that I wasn’t going to do that, and that I was going to fight back. I wasn’t going to let it define me, I used it has motivation to become a fighter. Sports are one of the things that have helped me the most, being as completive as I am helped me. I always wanted to make sure I was
Juvenile idiopathic arthritis (JIA) is the most common pediatric rheumatic disease and may result in significant pain and long term morbidity, and disability with persistent arthritis into adulthood . Prior to the mid 1990s, treatment involved nonspecific agents, many with signifcant adverse effects. In the new era of target specific biologic therapy, it is now possible to better tailor therapy for patients with JIA. Experience with these agents in Indian patients is scanty. This paper is a description of the clinical outcomes and challenges in way of treatment of JIA with biological agent at a single tertiary care center in north India. In developing countries like India, high cost of these novel molecules is the main obstacle in the path
As we grow older our bodies begin to degenerate, and stop working. There are many different kinds of diseases that we are subject to as we age, cancers, heart disease, Alzheimer’s disease, arthritis, and many others. All have a negative affect on our lives, making it difficult to function. Arthritis is the second leading chronic disease in the United States.
Arthritis is a joint disorder, which affects one or several joints in the body. The condition has more than one hundred types of diseases with osteoarthritis being the most common. Osteoarthritis results from joint infection, or age. Patients that suffer from arthritis complain about pain in the joints. In most cases, the pain remains constant in the affected joint. It is worth noting, “The pain from arthritis is due to inflammation that occurs around the joint, damage to the joint from disease, daily wear and tear of joint, muscle strains caused by forceful movements against stiff painful joints and fatigue” (Reid, Shengelia & Parker, 2012, p. 40). However, joint pain could result from various diseases, and in such