Post-Traumatic-Stress Disorder Analysis

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Our most vivid memories are those tied with strong emotional memory components. For those suffering from Post-Traumatic-Stress Disorder (PTSD), the emotional component of a memory makes recalling certain life events painful and debilitating. PTSD is an anxiety disorder that develops from the exposure to a traumatic event and often seen in comorbid patients also afflicted with alcoholism, depression, and general anxiety. Because this disorder is so debilitating, finding prevention treatments becomes essential to ensuring the mental health of so many individuals world-wide.
PTSD is a disorder that is closely associated with traumatic memories and events. In order to gain a deeper understanding of the biological mechanisms driving PTSD, it is vital to understand the plasticity of memory formation, consolidation, and reactivation. Multiple studies have documented that following the initial memory encoding stage, memory remains temporarily vulnerable to disruption until the consolidation phase (McGaugh, 2000). Diverse corticosteroid compounds (Aerni, et al., 2004) (Schelling, 2002) (Schelling, et al., 2001) (Schelling, et …show more content…

Diagnostic criteria for all PTSD symptoms includes indicators from each of four symptom clusters: intrusion, avoidance, negative alterations in cognitions and mood, and alterations in arousal and reactivity. Alterations in arousal and reactivity symptoms include hyperarousal, difficulty concentrating, hypervigilance, and exaggerated startle response (Friedman, Resick, & Brewin, 2011). Hyperarousal, hypervigilance, and avoidance, symptoms from two of the four respective clusters, are some of the most debilitating symptoms that can be easily demonstrated in animal models of PTSD, and thus commonly used for studying various potential treatments (Cohen, et al., 2012) (Cohen H. , 1969) (Andero & Ressler, 2012) (Yul, Zhang, Cuil, Cuil, & Zhang,

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