Primary Effects Of Rheumatoid Arthritis

Rheumatoid Arthritis or “RA” is an autoimmune disorder where the immune system mistakenly attacks its own body tissues. This disease affects the lining of joints causing pain and swelling. Eventually the swelling can lead to bone erosion and joint deformity. RA can happen to anyone at any age, but the majority of people who have to endure this disease are women over the age of 40.

Rheumatoid arthritis is a chronic syndrome that is characterized by inflammation of the peripheral joints, but it may also involve the lungs, heart, blood vessels, and eyes. The prevalence of this autoimmune disease is between 0.3% to 1.5% of the population in the United States (Feinberg, pp 815). It affects women two to three times more often than men, and the onset of RA is usually between 25 and 50 years of age, but it can occur at any age (Reed, pp 584). RA can be diagnosed by establishing the presence of persistent joint pain, swelling in a symmetric distribution, and prolonged morning stiffness. RA usually affects multiple joints, such as the hands, wrists, knees, elbows, feet, shoulders, hips, and small

Rheumatoid arthritis is a chronic, systemic inflammatory autoimmune disease. The disease happens when the immune system mistakenly attacks a healthy tissue as if it was a foreign invader, such as a virus or bacteria. If left untreated it can lead to permanent joint damage, decrease in quality of life, and total disability. It affects over a million people in the U.S. alone. Rheumatoid arthritis symptoms include persistent joint inflammation which causes joint pain, stiffness, and swelling. Fatigue and stiffness are usually early symptoms. Joint pain can be an early symptom in a variety of diseases. Symptoms of rheumatoid arthritis often develop slowly over a period of weeks or longer, but this is not always the case, it can have an acute

Rheumatoid arthritis is a chronic inflammatory disease affecting the joints, most often in the hands and feet. It results in swelling, stiffness, pain, and sometimes joint, bone, and cartilage destruction. Rheumatoid arthritis usually affects joints on both sides of the body equally, meaning if a joint on one side is affected, the same joint on the opposite side is affected as well. Rheumatoid arthritis belongs to a group of diseases called autoimmune disorders that affects joints. In rheumatoid arthritis, the immune system produces antibodies that attack the soft tissues lining of the joints. Eventually the cartilage, bone, and ligaments of the joint deteriorate, causing deformity, instability, and scarring within the joint

With rheumatoid arthritis there are many painful problems as well as symptoms and causes of this genetic disorder. First, the description of the disorder is how painful it can be. The painful swelling can lead to bone erosion, which means that the bone will wear away. Next, the symptoms of rheumatoid arthritis can be hard on the body. You could have fatigue (extreme tiredness), a fever, or weight loss. As well, you can have morning stiffness which can last for hours. Lastly, some causes of the disorder are that the immune system attacks the synovium which is the lining of the membrane that surrounds your joints. In other words, what happens is the synovium inflames which destroys the cartilage and bone in the joint. As you can see rheumatoid arthritis has many painful problems, symptoms and causes.

Living on this Earth, humanity may encounter many different viruses, and infectious diseases which have the potential to jeopardize a well-being. In regards to autoimmune diseases, these types of conditions are due to your body’s immune system fighting off its own self. One of the more unfortunate autoimmune diseases attacks joints, and it is called Rheumatoid Arthritis. This disease can cause normal everyday activities to become almost impossible to perform. With being diagnosed with RA, there will be complications that a person will be more susceptible to due to RA. Rheumatoid Arthritis has a very rich history that will be

Rheumatoid arthritis is a disease in which your joints are very sore and ache multiple times of the day. This disease is in the autoimmune system because the immune system mistakenly attacks your own body tissue and results in these pains. It ordinarily affects the small joints of your hands and feet. The lining of these joints is attacked and causes painful swelling. It also affects other organs such as your skin, eyes, lungs, and blood vessels. If not treated correctly it is known to cause bone deformity. Rheumatoid arthritis is predominantly more common in women and generally begins around age 40.

Rheumatoid arthritis is a disease that has direct involvement with the immune system. This disease is considered to be degenerative and currently the only thing that can be done is manage the painful symptoms and suppress the self targeting actions by using immune suppressing drugs. The cause of rheumatoid arthritis is mostly unknown but there is a high amount of evidence that there are genetic predispositions for the disease. This being said however there are also environmental factors to asses these include, bacteria, viruses, fungi and other environmental factors. Doctors primarily use a physical examination to first suspect R.A. then send for blood work to confirm. There are many aspects to this disease and many questions left

Arthritis is inflammation of your joints. Most symptoms include pain, stiffness aching, and swelling in or around the joints. Various forms of arthritis, such as rheumatoid arthritis and lupus, can affect most organs and cause extensive symptoms. The term arthritis includes countless rheumatic diseases and conditions. Rheumatoid arthritis is an autoimmune disorder that targets the lining of joints. It transpires when the protective cartilage on the ends of the bones wears down over time. The most common type of arthritis is osteoarthritis. Osteoarthritis is the tissue that covers the ends of bones where they form a joint. While osteoarthritis can damage any joint in the body, it typically affects joints in the spine, hands, knees and hips.

Rheumatoid arthritis is a condition that affects about 1.3 million people in America. It causes pain and swelling around the joints. Other rheumatoid arthritis symptoms include fatigue, tenderness and weakness in the joints. There are a number of rheumatoid arthritis treatments available. The goal of treatment is to control the condition and improve a patient's quality of life.

Signs and symptoms that occur with rheumatoid arthritis, vary from patient to patient depending on their progression stage and what factors contribute to their inflammation. Some examples of symptoms can include but are not limited to: swelling, stiffness, redness, deformity and pain of the joints, dryness, impaired vision, itchiness, burning and discharge coming from the eyes, damaged nerves, skin numbness, tingling and burning sensations, anemia, or a decreased production of red blood cells, and other physical symptoms can include fatigue, weight loss, a minor fever, loss of appetite and muscle aches.

Creative Biolabs offers the most comprehensive pre-clinical animal testing services for Rheumatoid Arthritis, which includes developing animal models of Rheumatoid Arthritis and lead drug candidates’ toxicity and efficacy evolutions in various species, even in highly challenging NHP. Our experts and scientists has plenty of experience in Rheumatoid Arthritis research and they would work closely with you on every step to choose and develop the most appropriate study plan for Rheumatoid Arthritis. We also provide preclinical service for Rheumatoid Arthritis studies, such as evaluation of RA based on the immunohistochemistry, and assessment of major immune factors such as IL-1, TNF-α, IL-10.

As the disease progresses it goes on to affect larger joints such as wrists, ankles, and then elbows, hips and shoulders, etc. Since RA affects the lining of your joints, it causes a painful swelling that in extreme cases can cause bone erosion and/or joint deformity. The Mayo Clinic further describes RA as “An autoimmune disorder, rheumatoid arthritis occurs when your immune system mistakenly attacks your own body's tissues. In addition to causing joint problems, rheumatoid arthritis sometimes can affect other organs of the body — such as the skin, eyes, lungs and blood vessels.” (“Diseases and Conditions: Rheumatoid arthritis: Definition”). This autoimmune disease can occur at just about any age, but most commonly strikes at the age of 40, and is fairly much more common in women versus men. The pattern of RA varies between each host. This meaning that it could be a continuous worsening of symptoms over time, or it could come and go in events often called “flare-ups”. The Mayo Clinic describes this sort of pattern as the following, “Rheumatoid arthritis signs and symptoms may vary in severity and may even come and go. Periods of increased disease activity, called flares, alternate with periods of relative remission — when the swelling and pain fade or disappear.” (“Diseases and Conditions: Rheumatoid arthritis: Symptoms”) Treatment for this disease revolves mostly around controlling symptoms, managing pain, and avoiding further joint damage at all costs with medication, physical therapy/rehabilitation, and keeping the patient

Although osteoarthritis is essentially the most original sickness that can influence the joints, rheumatoid arthritis also influences quite a few individuals. Rheumatoid arthritis is associated to a dysfunction within the immune process that impacts the joints' lining and in turn brings innovative wellness stipulations. Women are in most cases those who want some form of extreme joint suffering alleviation due to the fact that of this condition. The types of arthritis can range in the symptoms and remedy remedies. The discomfort that it will purpose is also

Arthritis most generally effect older adults. “Currently, an estimated 52.5 million US adults reported that their doctor told them they had arthritis. As our nation’s population ages, the prevalence is expected to increase.” (healthypeople, 2014). “Arthritis affects 1 in 5 adults and continues to be the most common cause of disability. It costs more than $128 billion per year. All of the human and economic costs are projected to increase over time as the population ages” (healthypeople, 2014).