Rheumatoid Arthritis Research Paper

Rheumatoid Arthritis(RA) is the most common type of autoimmune arthritis. RA is a progressive and debilitating musculoskeletal disorder that affects the joints symmetrically, causing a range of systemic effects. What it causes is still not well known; nevertheless, findings of new research points towards a believe that it is triggered by a defective immune system, which causes the release of inflammatory chemicals. These chemicals cause damage to cartilage and bone, usually affecting the wrists, the joints of the hand, including the knuckles, the middle joints of the fingers and feet. While this condition can affect any joints, besides, important body organs such as the eyes and the lungs can also be affected by the inflammation that occurs as a result of this chronic condition. Only in America 1.3 million of people are affected by this ailment, and 75 % of them are mainly women. Its onset usually occurs between fourth and sixth decades; however, RA can occur at any age("Diseases And

Rheumatoid arthritis is an autoimmune inflammatory disease which causes inflammation on joints leading to disability. The deterioration is caused by constant attack in the synovium leading to synovial cells to a rough and grainy tissue eventually allowing the bones to crumble away. The disease currently has no cure and scientists are thriving to find a target specifically aiming at the bones.

Rheumatoid arthritis is a systemic disease that affects whole systems of body particularly cardiovascular system, nerves, respiratory system (RACGP, 2009). The causes of rheumatoid arthritis are unknown but it is hereditary which assists to have a risk of rheumatoid arthritis by 50%-60% (RACGP, 2009).

Rheumatoid arthritis is very painful and is a long lasting condition. Symptoms of Rheumatoid arthritis can go away and then return. It happens in the immune system; the joints are targeted and become inflamed. The cause of

Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints. While inflammation of the tissue around the joints and inflammatory arthritis are characteristic features of rheumatoid arthritis, the disease can also cause inflammation and injury in other organs in the

Rheumatoid arthritis is a chronic syndrome that is characterized by inflammation of the peripheral joints, but it may also involve the lungs, heart, blood vessels, and eyes. The prevalence of this autoimmune disease is between 0.3% to 1.5% of the population in the United States (Feinberg, pp 815). It affects women two to three times more often than men, and the onset of RA is usually between 25 and 50 years of age, but it can occur at any age (Reed, pp 584). RA can be diagnosed by establishing the presence of persistent joint pain, swelling in a symmetric distribution, and prolonged morning stiffness. RA usually affects multiple joints, such as the hands, wrists, knees, elbows, feet, shoulders, hips, and small

An autoimmune disorder, Rheumatoid Arthritis occurs when your immune system mistakenly attacks your own body's tissues. Unlike the wear-and-tear damage of osteoarthritis, rheumatoid arthritis affects the lining of your joints, causing a painful swelling that can eventually result in bone erosion and joint deformity. “Rheumatoid arthritis.” Mayo Clinic, Mayo Foundation for Medical Education and Research, 9 Aug. 2017, www.mayoclinic.org/diseases-conditions/rheumatoid-arthritis/symptoms-causes/syc-20353648

Thank you Prianca for taking the time to share about the cytokines and their interaction in the inflammatory process of the Rheumatoid Arthritis. Indeed, the epidemiology incidence of Rheumatoid arthritis (RA) is increasing every minute. Like you well explain above in your post, we have more than 1.3 million of people in the US affected with RA (Ruderman & Tambar, 2013) and 1 percent of the worldwide population is affected with RA (Lubberts & Berg, 2003). It seems like this epidemic is going to continue. 75 percent of that 1.3 million are women, and statistically, 1 of 3 women may get rheumatoid arthritis in their life. Rheumatoid arthritis can affect anybody at any age, but in most of the cases, the disease begins in the 40’s and 60’s (Ruderman & Tambar, 2013).

may become more and more difficult. It is important to treat and diagnose rheumatoid arthritis as soon as possible. The joint damage of rheumatoid arthritis is not just progressive, but is hidden. The amount of joint damage increases quickly. The synovial membrane thickens and accumulates synovial fluid, which can cause pain and tenderness in the peripheral joints. The membrane then produces an abnormal granulation tissue called pannus.

The immune system normally makes antibodies for attacking bacteria and viruses which help to fight infections. In rheumatoid arthritis, the immune system mistakenly sends antibodies to the lining of the joints which attacks the tissue surrounding the joint causes inflammation. Inflammation in rheumatoid arthritis is a long-term condition. So, this thin layer of cells covering your joints to become sore and swollen, releasing chemicals that damage bones, cartilage, tendons, and ligaments. This condition should be treated quickly if not, these chemicals will lose shape and position and it can destroy the joints completely. The risk of developing more rheumatoid arthritis by smoking, eating lots of red meat and drinking lots coffee etc. Even the genes that you inherit from your parents can have the risk developing rheumatoid arthritis.

To begin with, rheumatoid arthritis is a disease that can be spread by genetics, hormones, lifestyle, and environment. Scientists don’t know what exactly causes rheumatoid arthritis, but they do know it’s the result of an autoimmune disorder. An autoimmune disorder is created when immune cells start to attack the body. With rheumatoid arthritis, the body attacks its own healthy joint tissue called the synovia. The synovia is what makes a clear liquid substance known as synovial fluid. Synovial fluid lubricates healthy joints and gives cartilage and bones the nourishment needed to remain effective and mobile. When rheumatoid arthritis starts antibodies are made and begin to release chemicals that cause inflammation to the synovia, stopping its ability to make its synovial fluid. The less amount of synovial fluid that’s made, the more

Arthritis is inflammation of your joints. Most symptoms include pain, stiffness aching, and swelling in or around the joints. Various forms of arthritis, such as rheumatoid arthritis and lupus, can affect most organs and cause extensive symptoms. The term arthritis includes countless rheumatic diseases and conditions. Rheumatoid arthritis is an autoimmune disorder that targets the lining of joints. It transpires when the protective cartilage on the ends of the bones wears down over time. The most common type of arthritis is osteoarthritis. Osteoarthritis is the tissue that covers the ends of bones where they form a joint. While osteoarthritis can damage any joint in the body, it typically affects joints in the spine, hands, knees and hips.

Arthritis occurs when the body incorrectly identifies its own tissue as foreign matter and attacks it. Arthritis includes a set of more than eighty autoimmune diseases. Arthritis attacks connective tissues and joints. It causes stiffness, pain, inflammation, and swelling of the joints. Some kinds are crippling, but rarely leads to death. There are many different

Rheumatoid arthritis is a form of autoimmune disease – these diseases are characterized by the inappropriate activation of the immune response against normal tissues in the body. This leads to tissue and joint inflammation, especially in the hands and wrists. Inflammation causes joint stiffness, immobility, and pain – long-term inflammation can lead to scarring and bone destruction.

Rheumatoid arthritis is a disease where the body’s immune system attacks the joints and other healthy cells. This creates inflammation inside of the joints, which then causes swelling and pain in and around the joints. If inflammation goes unchecked,