Rheumatoid Arthritis is an autoimmune disease and chronic inflammatory illness that causes the body’s immune system to attack its joints rather than the usual foreign substances such as viruses and bacteria (Arthritis Foundation, 2015; Mayo Foundation, 1998-2015). Unlike wear-and-tear osteoarthritis, Rheumatoid Arthritis attacks the lining of the joints and often other body tissues such as the heart, skin, eyes and lungs (Arthritis Foundation, 2015; May Foundation, 1998-2015). Due to the body’s normal immune response, redness, inflammation, pain, and swelling, arise and can ultimately result in the destruction of bone and joint, causing for deformity (Mayo Foundation, 1998-2015). In the United States, about 1.5 million people have Rheumatoid Arthritis (Arthritis Foundation, 2015). Within this population, women are three times more likely to experience this than men. It has been noted to commonly occur between the ages of 30-60 for women and later in life for men (Arthritis Foundation, 2015). Men may be protected by hormonal factors and require a stronger genetic component to develop disease. Rheumatoid Arthritis is thought to stem from a combination of genetic susceptibility and exposure to an appropriate environmental trigger. (Ollier, W. E., Harrison, B., & Symmons, D. 2001). Within the aspect of genetics it is most likely hereditary. Although infectious triggers of RA have long been suspected, no definitive evidence has been obtained. Previous blood transfusion,
Rheumatoid arthritis is a systemic disease that affects whole systems of body particularly cardiovascular system, nerves, respiratory system (RACGP, 2009). The causes of rheumatoid arthritis are unknown but it is hereditary which assists to have a risk of rheumatoid arthritis by 50%-60% (RACGP, 2009).
Rheumatoid Arthritis or “RA” is an autoimmune disorder where the immune system mistakenly attacks its own body tissues. This disease affects the lining of joints causing pain and swelling. Eventually the swelling can lead to bone erosion and joint deformity. RA can happen to anyone at any age, but the majority of people who have to endure this disease are women over the age of 40.
Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints. While inflammation of the tissue around the joints and inflammatory arthritis are characteristic features of rheumatoid arthritis, the disease can also cause inflammation and injury in other organs in the
Rheumatoid Arthritis(RA) is the most common type of autoimmune arthritis. RA is a progressive and debilitating musculoskeletal disorder that affects the joints symmetrically, causing a range of systemic effects. What it causes is still not well known; nevertheless, findings of new research points towards a believe that it is triggered by a defective immune system, which causes the release of inflammatory chemicals. These chemicals cause damage to cartilage and bone, usually affecting the wrists, the joints of the hand, including the knuckles, the middle joints of the fingers and feet. While this condition can affect any joints, besides, important body organs such as the eyes and the lungs can also be affected by the inflammation that occurs as a result of this chronic condition. Only in America 1.3 million of people are affected by this ailment, and 75 % of them are mainly women. Its onset usually occurs between fourth and sixth decades; however, RA can occur at any age("Diseases And
Rheumatoid arthritis is a chronic syndrome that is characterized by inflammation of the peripheral joints, but it may also involve the lungs, heart, blood vessels, and eyes. The prevalence of this autoimmune disease is between 0.3% to 1.5% of the population in the United States (Feinberg, pp 815). It affects women two to three times more often than men, and the onset of RA is usually between 25 and 50 years of age, but it can occur at any age (Reed, pp 584). RA can be diagnosed by establishing the presence of persistent joint pain, swelling in a symmetric distribution, and prolonged morning stiffness. RA usually affects multiple joints, such as the hands, wrists, knees, elbows, feet, shoulders, hips, and small
Many people all over the world may have rheumatoid arthritis. Rheumatoid Arthritis is a chronic inflammatory disorder that affects the small joints in the hands and feet (Mayoclinicorg, 2015). It is also an autoimmune disease, where the immune system sees the body as a foreign object and attacks it (Mayoclinicorg, 2015). As the chronic disorder matures, it could seep into the blood vessels and into other organs: heart, lungs, skin, and eyes (Mayoclinicorg, 2015). This chronic pain is found mostly in women around forty to sixty years old; however, men with low testosterone could also have the chronic disorder (Mayoclinicorg, 2015). Because smokers burn off certain cells to prevent infection, they are also at risk for rheumatoid arthritis. This
Do you ever find yourself feeling limited to everyday activities due to throbbing in you joints? Do you ever wake up and find yourself battling with pain and stiffness? Well, just know you are not alone. All across America, thousands of people are affected by this disease every year. Generally, those who suffer the most from this chronic disease are ages 65 and over. Rheumatoid arthritis is taking a major toll on the lives of many senior citizens. Don’t let the swelling of your joints stop you from feeling young again.
Rheumatoid arthritis is a chronic inflammatory disease affecting the joints, most often in the hands and feet. It results in swelling, stiffness, pain, and sometimes joint, bone, and cartilage destruction. Rheumatoid arthritis usually affects joints on both sides of the body equally, meaning if a joint on one side is affected, the same joint on the opposite side is affected as well. Rheumatoid arthritis belongs to a group of diseases called autoimmune disorders that affects joints. In rheumatoid arthritis, the immune system produces antibodies that attack the soft tissues lining of the joints. Eventually the cartilage, bone, and ligaments of the joint deteriorate, causing deformity, instability, and scarring within the joint
Definition: Rheumatoid arthritis is a chronic inflammatory disorder, which affects the small joints of hands and feets, and the lining of joints that causes painful swelling. The swelling can eventually result in bone erosion and joint deformity. It’s an autoimmune disorder, in which the immune system mistakenly attacks own body 's tissues. Rheumatoid arthritis not only causes a joint problem, but it can also affect other organs of the body such as the skin, eyes, lungs, and blood vessels.
Rheumatoid arthritis (RA) is an autoimmune disease where the body’s immune system protects the body’s health by attacking unknown substances like bacteria and viruses, and mistakenly attacks the body’s joints. This creates inflammation causing the tissue that lines the inside of joints to thicken, which results in swelling and pain in and around the joints. The tissue makes a fluid that lubricates joints and helps them move smoothly. If inflammation goes unchecked, it can damage cartilage, the elastic tissue that covers the ends of bones in a joint, as well as the bones themselves. Over time, there is loss of cartilage, and the joint spacing between bones may become smaller. Joints can become
Rheumatoid arthritis is an autoimmune disease. normally the body’s immune system attacks and protects the body against foreign substance, with RA the immune system accidently attacks the joints. When the joints are mistakenly attacked inflammation occurs which causes the tissues to thicken thus resulting in pain and swelling of the joints. When this inflammation is undetected damage to the cartilage can occur, when this happens the spacing between the bones become smaller, the joints may become loose, painful, unstable and may also lose their mobility and deformity of the joints can occur.
Gradually, the joint loses its shape and alignment. Doctor’s don’t know what causes this process to start, but it could be a genetic component. Your genes don’t cause the arthritis, but they can make you more susceptible to environmental factors, such as infection with certain viruses and bacteria that may trigger the disease. If a member of your family has the disease you are more likely to get it also. Rheumatoid arthritis can range from mild to severe. In most cases it is chronic, which means it lasts a long time even a lifetime. Scientists estimate the about 1.5 million people, or about 0.6 percent of the U.S. adult population have rheumatoid arthritis, according to the National Arthritis Data Workgroup. It occurs in all races and ethnic groups. Although the disease starts in mid-life, older teenagers and young adults may also be diagnosed with the disease. About two to three times as many women as men have the disease. Rheumatoid arthritis is primarily a disease of the joints. A joint is the point where two or more bones come together which is supposed to protect your immune system, the body from infection and disease, attacks joint tissues for unknown reasons. White blood cells, travel to the synovial and cause inflammation (synovitis), which causes the warmth, redness, swelling, and pain. As rheumatoid progresses, the inflamed synovium invades and destroys the cartilage and bone
The Autoimmune disease, Rheumatoid arthritis can be hereditary but other than that there is not enough research to understand what causes the disease. Usually the human immune system fights off and protects the body from infection however an autoimmune disease is when the body’s immune system begins to attack healthy tissues instead of aiming for foreign matter, for example an infection. In Rheumatoid arthritis, the immune system attacks the lining of joints (knee, elbows, ankles, wrists, fingers, etc). The tissue in the joints is what the immune system attacks, called the synovial membrane; this causes inflammation and damage of joints. Nanoparticles are 10 ^-9 which is 1 billionth of a meter. There are 25,400,000 nanometers in an inch. Figure
Rheumatoid arthritis is a disease that has direct involvement with the immune system. This disease is considered to be degenerative and currently the only thing that can be done is manage the painful symptoms and suppress the self targeting actions by using immune suppressing drugs. The cause of rheumatoid arthritis is mostly unknown but there is a high amount of evidence that there are genetic predispositions for the disease. This being said however there are also environmental factors to asses these include, bacteria, viruses, fungi and other environmental factors. Doctors primarily use a physical examination to first suspect R.A. then send for blood work to confirm. There are many aspects to this disease and many questions left
Hi Kerri, Thanks for your reply. As I mentioned in rheumatoid arthritis (RA), this is an chronic inflammatory disease condition that affects the synoviyal membranes of joints and other organs in the body such as heart , immune system, musculoskeletal system and respiratory system (Stark 2014).