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Sepsis Case Study Essay

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Sepsis is one of the main causes of mortality and morbidity in preterm babies and is responsible for 45% of late deaths in the neonatal intensive care units (NICUs).1 early diagnosis and management of sepsis are a great challenge facing neonatologists. Clinical diagnosis is difficult due to non specific symptoms and signs while laboratory diagnosis is time consuming.2

Blood culture is the gold standard diagnostic method of neonatal sepsis. However, technical problems as insufficient blood sample or maternal use of antibiotics can be an obstacle in isolating the responsible pathogens.
In recent years, there has been great interest in studying new indicators of infection such as interleukin-6 (IL-6), IL-8, and procalcitonin (PCT) and their

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