Smallpox And The Epidemic Of Smallpox

The history of vaccinations begin with Edward Jenner, the country doctor from Gloucestershire who found, growing on cows, a nearly harmless virus the protected people from smallpox. Jenner’s vaccine was safer, more reliable, and more durable than variolation, and it is still the only vaccine to have eliminated its reason for being-in 1980, when the World Health Organization (WHO) declared the disease extinct. For nearly a century and a half, smallpox was the only vaccine routinely administered, and it saved millions of lives . But the controversy that marked the return of the vaccine, amid bioterrorism hysteria in 2002, was only the latest twist in the remarkable, mysterious life of vaccines.

Over many of years the world has faced problems concerning health. Many scientists and health experts have worked together to better our nation 's health care. English Physician and Scientist Edward Jenner, a small country doctor, who is well known around the world for his innovative contribution to immunization and the ultimate eradication of smallpox. (2005, Baylor University Medical Center.) It is believed that smallpox appeared around 10,000 B.C. Smallpox was introduced to Europe sometime between the fifth and seventh centuries and was frequently epidemic during the Middle Ages. Edward Jenner was born on May 17, 1749, in Berkeley, Gloucestershire. During his early school years, Edward developed a strong interest in science and nature that continued throughout his life. Jenner’s interest in natural history and animal biology sharpened his medical understanding of the role of human-animal trans-species boundaries in disease transmission. He experienced the proverbial “Eureka”-like moment sometime during the 1770s. At age 13 he was apprenticed to a country surgeon and apothecary in Sodbury, near Bistol. The record shows that it was there Jenner heard a dairymaid say, " I shall never have smallpox for I have had cowpox. I shall never have an ugly pockmarked face." While Jenner 's interest in the effects of cowpox began during his apprenticeshire with George Harwickle, it wasn 't until 1796 before he made the first step in a long process of smallpox would be exposed. Jenner

Vaccinations have been actively used for over 200 years now and have been effective for over 200 years as well. Western medicine’s introduction to the practice is said to have occurred within the eighteenth century, when a traveling British aristocrat, Lady Mary Wortley Montagu, reported her observations of Turkish children being injected with pus from smallpox victims. Although this practice seemed quite harsh, most of these children would contract only a mild version of the illness. In return, these recipients would retain a lifelong immunity to this terrible disease (World of Microbiology & Immunology). Similarly, in the United States, a Puritan minister by the name of Cotton Mather learned about inoculation from his African slave, Onesimus. Onesimus claimed that he was inoculated with smallpox pus and never caught the tragic disease (Williams). This type of medicinal treatment was initially rejected by most Western practitioners. They felt it was a dangerous and barbarous practice, but vaccination gained a tremendous amount of support at the turn of the nineteenth century when English physician Edward Jenner created a new smallpox vaccine derived from the relatively mild cowpox virus (Riedel). There’s no doubt that history has shown the positive outcomes of immunization and continued to show them as technology and medicine progressed.

During the Revolutionary War, one of the main fears were not the enemies bullets, but fear of disease. One of the major viruses that people had to fear was smallpox. The continental army had more to fear than the British in the fact that British had been immunized, and the continental army had not. This was only the beginning of the problems from the smallpox epidemic that broke out in America.

Vaccines have been used to prevent diseases for centuries, and have saved countless lives of children and adults. The smallpox vaccine was invented as early as 1796, and since then the use of vaccines has continued to protect us from countless life threatening diseases such as polio, measles, and pertussis. The Center for Disease Control and Prevention (2010) assures that vaccines are extensively tested by scientist to make sure they are effective and safe, and must receive the approval of the Food and Drug Administration before being used. “Perhaps the greatest success story in public health is the reduction of infectious diseases due to the use of vaccines” (CDC, 2010). Routine immunization has eliminated smallpox from the globe and

Smallpox, also know as variola virus, is extremely contagious and lethal. In modern day it has been eradicated and we no longer vaccinate the human population. Symptoms begin 12-14 days after infection; after 1-2 days spots turn into blisters and then pustules and after 8-9 days these pustules become crusted. If the person survives, large disfiguring scars remain (Merck, 2003).

Smallpox is a viral infection caused by Variola major. This infection is currently one of the most dreaded diseases, and is believed to be more dangerous than the enemy’s sword. The exposure is usually an infection of the respiratory tract. After exposure, early symptoms are: headaches, back aches, fever, vomiting, discomfort, and feeling out of sorts. These symptoms go away usually in two days, and the patient feels better. Then about two days later, the patient has a flustered face, and lesions on the mouth, throat, and nasal membranes. At 5 days past exposure, red rashes and bumps appear on the skin, bleeding through skin, and mucous membranes. If the patients bleeds through their eyes, gums, or nose, the patient will not live much longer, but that is not usually the case. The bumps may touch each other or they may be separate from each other. If the bumps do not touch, the patients has a good chance of surviving. But if the bumps do touch, the patient has a forty percent chance of surviving. Dehydration is common in patients because it may be painful or difficult to drink. Around day ten, the bumps will become soft, and blisters will form. The fluid in the bumps is absorbed because of dehydration. A smell often comes from cracked bumps, and a second bacterial infection may occur due to the openings in the body. Two weeks after initial symptoms, the bumps and blisters are replaced by scabs. One week later the fever disappears, the patient returns to a normal life, and the

Jenner’s vaccine was so successful that the World Health Organization declared the word “entirely eradicated” of human smallpox on December 9, 1979 (Spier, 2015). As a consequence of this monumental success and other successes like it, people forget how deadly diseases like this can be and fail to attribute their lack of a crippling disease to vaccinations. Other diseases that have been considered eliminated in a similar manner to smallpox are: diphtheria, tetanus, pertussis, polio, measles, mumps, rubella, hepatitis A & B, yellow fever (Spier, 2015).

The earliest indicator of smallpox in history is the extensive lesions on three Egyptian mummies. There are also recorded cases from the Hitties (1346 BC), Syracuse (595 BC), Athens (490 BC), China (48AD), Korean Peninsula (583 AD), and Japan (585 AD), however, they are not definite cases because these ancient physicians were unable to distinguish smallpox rashes from other skin rashes. Nevertheless, this distinction was made in 910 AD by physician Al-Razi. As Islam spread across North Africa and the Iberian Peninsula, smallpox followed. By 1000 AD, smallpox epidemics were widely recorded from Japan to Spain. In the 16th century, smallpox outbreaks hit large cities such as London and Geneva, and exploration across oceans facilitated the spread of smallpox as well to the Americas, Australia, and South Africa. In the Americas, natives were seen as lesser and put to work in mines and on plantations where the combination of poor working conditions and European disease thinned out their population. This encouraged the importation of slaves from Africa as replacements and eventual establishment of slave trade to the New World. Smallpox outbreaks killed many natives, starting in Hispaniola and spreading to Cuba, the Yucatan, and other parts of Mexico. The spread was almost systematic, and due to the nature of smallpox, affected isolated, indigenous populations. Even after Edward Jenner created a successful vaccine for smallpox, it remained a serious threat, as many people, especially in rural areas were not

This article was unique to read because it was actually selected excerpts from the Cumberland House journals of 1781 and 1782. Each excerpt described what kind of person was being affected such as age and gender and then described where the smallpox rash was first noticed. Smallpox was first brought to Mexico by the Spaniards in 1520, later reached Massachusetts and extended west a century later. On each occasion, it occurred in an epidemic form with an extremely high mortality rate. This article describes the first recorded smallpox epidemic on the western plains. The excerpts were handwritten diaries of daily events. The chroniclers were William Tomison and Matthew Cocking. Tomison’s account of the smallpox epidemic just 20 years before Jenner

With the major strides in medicine that have come about in the last few decades, the notion of a plague seems to be becoming less of a possibility and more a thing of antiquity. Around the latter half of the 20th century, doctors thought that disease as a whole would be eradicated with the new vaccinations and antibiotics that were being produced. For the first time in history it seemed as if diseases were under control. It was not long before the arrogance of modern medicine found new epidemics that were not so easily cured. To this day the only disease to be eradicated is smallpox, which was announced in the 1980s. Decades after achieving the eradication of small pox in nature, new pathogens like SARs, AIDS/HIV,

Armed with opposable thumbs and high-functioning frontal lobes, humans have historically battled disease, including the “the speckled monster”; smallpox. Known as a highly contagious virus, smallpox has been around since 10,000 B.C., and its plagues are responsible for causing millions of deaths. There was no knowledge of how to treat or prevent this disease from spreading until the idea of taking samples of dead smallpox cells and injecting them into a human was proven to build immunity. Over time, the treatment was perfected and has changed medical history by introducing the idea of the vaccine. Smallpox vaccinations eventually became mandated, and in 1979, smallpox was declared to be the first disease to ever be completely eradicated from

The brutal symptoms of smallpox reveal why the disease is known as one one of the deadliest in history. Smallpox slowly deteriorates the victim in distinct symptom stages. Symptoms begin to display after approximately ten days since the victim was exposed to the Variola virus. Suddenly, the victim will feel flu-like symptoms including headache, fever, overall discomfort, severe back pain, vomiting, and severe fatigue (“Smallpox.”). Brutal symptoms such as these, unfortunately, are only the beginning for a terrible disease such as smallpox. Next, symptoms become much more visible. After a day or two the forearms, face, and hands will develop flat, red spots. Red spots will eventually develop into small to moderate blisters which are

Imagine a quick spreading rash throughout the entire body, leaving not a single space behind; every opening and crevice in your body, including your mouth and eyes covered in painful bumps accompanied by high fever and severe body aches. Flat red spots transforming into fluid-filled lesions and soon oozing out yellow pus, evidently emitting a pungent odor to anyone who dared get close. The live virus present in the darkening crusty scabs that would soon fall off only to leave behind a deep pitted scarred filled complexion on anyone who was fortunate enough to survive. These scars would be forever remembered as the hallmark for the smallpox epidemic which tormented the world for over 3,000 years. (Riedel “Deadly Diseases”).

Over the past seventy years, a major practical problem in medical science was dealing with infectious diseases. Many human communicable infections are caused by microscopic organisms either bacteria or viruses. Immunization is the most outstanding and cost effective means for fighting infection caused by micro -organisms (Ragan & Duffy, 2012, p.22). Like every medication, vaccines have benefits and risks, and although highly effective, no vaccine is 100 percent safe in all individuals. However, adverse side effects of vaccination are significantly less than the risk of the serious illnesses caused by infectious diseases. The effectiveness of immunization