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Smallpox Virus

Better Essays

Jamie Lucas
Jeff Foster
Microbiology
March 9, 2017
SMALLPOX
Smallpox is caused by the variola virus an extremely contagious disease. That can be spread through any type of contact with the virus. The virus is a member of the genus Orthopoxvirus, in the Poxviridae family. Smallpox has been considered eradicated in the United States since 1972. Virologists have speculated that it evolved from an African rodent poxvirus 10 millennia ago. The name is derived from the Latin word for "spotted" and refers to the raised bumps on the face and body of the patient. (Medscape.com) Smallpox has been to blame for the extinction and almost extinction of many cultures. The disease has been used as biological warfare since the beginning or war. At times, …show more content…

Given its rapid and deadly spread, conquers would place an exposed garment within enemy territory and wait. The virus would wipe out entire civilizations in a matter of months. Smallpox spreads rapidly throughout the lymph nodes. The infected person will remain asymptomatic through day 3-4 while the virus works its way through the spleen and bone marrow. This makes for a somewhat anonymous attack. Infection only requires a brief encounter with an exposed person or object. The exposer could appear to be completely healthy. Symptoms do not begin to surface until the 8-12th-day toxemia and fever are occurring. The virus then localizes in the small blood vessels of the dermis. In the earlier years, these symptoms were often confused with other illness. It isn't until approximately day 14, the patient is apparently infectious. The spleen, liver, kidneys, bone marrow and other viscera will contain large amounts of the virus. Lesions on the skin start forming as the capillaries dilate and the endothelial tissues swell. Now, even a lay person can make a visual diagnosis. The plasma cells and macrophages can be seen. The cells increase in size, the cell membranes rupture, leading to vesicular lesions. Migration of polymorphonuclear cells into the vesicles cause postulation. A pustule becomes slowly desiccated causing the crusty/scabby appearance of the lesions. The progression of the disease makes it the perfect weapon. At the point in time that the first infected person is visually diagnosed, they have potentially infected numerous people around them. Causing the deadly virus to almost instantly reach epidemic proportions. In the early days of Smallpox, someone or something had to be the contaminant jeopardizing both civilizations. Today with the conveniences we have such as air travel, running water, and complete mobilization the virus could be easily placed in our society. Given our

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